Afshin Samali

Ceremony to accredit Iran's ambassador postponed The new Iranian ambassador to Ireland has been prevented from officially taking up their duties by the Department of Foreign Affairs because of the regime's response to protests in Iran.

Ceremony to accredit Iran's ambassador to Ireland postponed - New Iranian ambassador has been prevented from officially taking up duties because of the regime's response to protests in Iran.
#Iran #DigitalBlackoutInIran #HumanRights #Solidarity
www.rte.ie/news/ireland...

Over 12,000 feared dead after Iran protests, as video shows bodies lined up at morgue Information trickling out of Iran suggests a far deadlier crackdown on protesters than previously reported.

At least 12,000, and possibly as many as 20,000 people have been killed in Iran in recent day.
KILLINGS must STOP!
#Iran #DigitalBlackoutInIran #HumanRights #Solidarity
www.cbsnews.com/news/iran-pr...

Tehran out strong: A video obtained by Iran International shows that despite harsh repression and an internet blackout, people in Punak, Tehran gathered together, lit fires, and chanted protest slogans.

Tehran, Iran — crowds protest the ruling regime.

Iran Under Growing Pressure Amid Protest Death Toll and Reports of Imminent Execution Rights groups warn that if executions proceed, Iran could face deeper international isolation and escalating tensions with Western governmen

Iran Under Growing Pressure Amid Protest Death Toll and Reports of Imminent Execution

www.onestnetwork.com/post/iran-un...

The Refugee-led Innovation Fund welcomes a new cohort of changemakers Across the world, organizations led by displaced and stateless people are innovating to support their communities. We’re right beside them.

The Samali Foundation is pleased to be one of the recipients of the Refugee-led Innovation Fund 2025-2026
medium.com/@UNHCRInnova...

Over $1B pledged to UNHCR today is a strong signal of solidarity with people forced to flee.

This is a crucial start for 2026, but we need this momentum to grow because funding gaps still put millions at risk.

ℹ️ www.unhcr.org/news/press-r...

Grelet honored by international society for ‘groundbreaking’ work in mitochondrial biology | USA Health In his presentation, “Nerve-to-Cancer Mitochondrial Transfer: A Key Driver of Metastasis,” Grelet revealed a transformative mechanism by which neurons transfer their mitochondria to cancer cells, fuel...

Grelet honored by international society for ‘groundbreaking’ work in mitochondrial biology- Nerve-to-cancer mitochondrial transfer #mitochondria #cancer #metastasis

www.linkedin.com/redir/redire...

NF-κB is a central regulator of hypoxia-induced gene expression | EMBO reports imageimageHypoxia induces a specific NF-κB-dependent gene signature across multiple cell systems. NF-κB is required for over 60% of gene repression occurring in response to hypoxia, controlling oxidat...

NF-κB is a central regulator of hypoxia-induced gene expression | EMBO reports www.embopress.org/doi/full/10....

€750m ‘Inspire’ investment aims to transform Ireland’s research infrastructure Today saw the lunch of a new €750m investment fund to ensure Ireland's higher education sector has the equipment and infrastructure required to compete globally.

The programme is designed to invest in research equipment from routine equipment that is used in higher education institutions to more advanced equipment that can be shared across several institutions as well as being accessible to external users.

🎓 Want to do a PhD in cancer biology?
ARC, @universityofgalway.bsky.social offering 2 funded #PhD positions (€25k + fees) starting in 2026.
Focus: #IRE1 signaling in breast cancer.
Apply by 12 Dec 2025
📧 afshin.samali@universityofgalway.ie
#CancerResearch #TNBC #MolecularBiology #PhDPositions

🎓 Want to do a PhD in cancer biology?
ARC, @universityofgalway.bsky.social offering 2 funded #PhD positions (€25k + fees) starting in 2026.
Focus: #IRE1 signaling in breast cancer.
Apply by 12 Dec 2025
📧 afshin.samali@universityofgalway.ie
#CancerResearch #TNBC #MolecularBiology #PhDPositions

2025 summer students in Cambridge

🔬 Experience Research Life at Cambridge!

Applications are now open for the 2026 Experience Postgrad Life Sciences Programme. Gain hands-on lab experience with an 8-week summer placement, in partnership with @corpuscambridge.bsky.social!

🔗 www.exppg.lifesci.cam.ac.uk

#SummerPlacement #Cambridge

First-ever atlas of brain development shows how stem cells turn into neurons
There are 6 excellent human brain development papers in Nature - www.nature.com/articles/d41... Check them out!

www.nature.com/articles/s41...

Breastfeeding boosts immune cells that protect against breast cancer The protective, long-lived T cells can persist for decades after a woman gives birth.

Breastfeeding boosts anticancer immunity through recruitment of CD8+ T cells
www.nature.com/articles/d41...

mRNA covid vaccines spark immune response that may aid cancer survival An analysis of patient records suggests that mRNA covid-19 vaccines boost the immune response to cancerous tumours when given soon after people start a type of immunotherapy, extending their lives

An analysis of patient records suggests that mRNA covid-19 vaccines boost the immune response to cancerous tumours when given soon after people start a type of immunotherapy, extending their lives

Why the next generation of mRNA vaccines is set to be even better

Scientists are designing mRNA vaccines to produce virus-like nanoparticles, which should lead to a more robust immune response with even fewer side effects than either of these immunisation approaches on their own

Blood tests are now approved for Alzheimer’s: how accurate are they? A second blood test has been been approved by the US Food and Drug Administration to assist in diagnosing Alzheimer’s disease. Will these tests change how cognitive decline is measured?

A new blood test has been been approved by FDA to assist in diagnosing Alzheimer’s disease.
go.nature.com/47b4hIp

Blood tests are now approved for Alzheimer’s: how accurate are they? A second blood test has been been approved by the US Food and Drug Administration to assist in diagnosing Alzheimer’s disease. Will these tests change how cognitive decline is measured?

A new blood test to aid with the diagnosis of Alzheimer’s disease has been approved by the US FDA

go.nature.com/47b4hIp

Dissecting Branch-Specific Unfolded Protein Response Activation in Drug-Tolerant BRAF-Mutant Melanoma using Data-Independent Acquisition Mass Spectrometry Cells rely on the Unfolded Protein Response (UPR) to maintain ER protein homeostasis (proteostasis) when faced with elevated levels of misfolded and aggregated proteins. The UPR is comprised of three ...

Dissecting Branch-Specific Unfolded Protein Response Activation in Drug-Tolerant BRAF-Mutant Melanoma using Data-Independent Acquisition Mass Spectrometry - Molecular & Cellular Proteomics www.mcponline.org/article/S153...

This gene causes obesity — and shields against heart disease People with certain forms of the MC4R gene have lower cholesterol levels than do other individuals with a high body-mass index.

Obesity gene shields against heart disease
www.nature.com/articles/d41...

Science Week Decorative graphic

The countdown to Science Week 2025 is on 🔬🗓️

Supported by Research Ireland, Science Week is marking its 30th anniversary this year!

Festival and event details are coming soon! Stay tuned and keep an eye on www.scienceweek.ie for the latest updates.

#ScienceWeek #ThenTodayTomorrow

More than 30% of this century’s science Nobel prizewinners immigrated: see their journeys The most common destination for eventual Nobel laureates in physics, chemistry and medicine since 2000 is the United States, Nature has found.

How #immigration drives winning #science - "Talent can be born anywhere, but opportunities are not" www.nature.com/articles/d41...

Since 2019, POI has worked to accelerate the development of personalised cancer therapy & diagnostic options. Today we begin Stage 2 of our journey, building on strong foundations and expanding our collaborations to drive innovation & shape the future of cancer care.

Siobhan Gaynor, Advanced Cancer Patient Council member and patient researcher; Prof Donal Brenan, UCD Professor of Gynae-Oncology, Consultant Gynaecological Oncologist at the Mater Hospital, and Deputy-Director of POI; Prof Walter Kolch, Director of Precision Oncology Ireland and Systems Biology Ireland (based at UCD); Dr Siobhan Roche, Director of Science for the Economy, Taighde Éireann–Research Ireland; Prof Kate Robson Brown, UCD Vice-President for Research, Innovation and Impact.

Minister James Lawless has launched Phase 2 of Ireland’s leading and largest ever cancer research programme, @precisiononcire.bsky.social. The programme is co-funded through Research Ireland, industry and the not-for-profit sector. Read more: www.researchireland.ie/news/precision-oncology-ireland/

Since 2019, POI has driven huge research impacts, from biological insights to training the next generation of researchers. On #WorldCancerResearchDay, we’re proud to share our new brochure, developed with science journalist Claire O'Connell, highlighting these achievements

tinyurl.com/jnhs762h

Trump links autism and Tylenol: is there any truth to it? The US president repeatedly advised people, “Don't take Tylenol,” but scientists say that strong evidence between the medication and autism is lacking.

No strong evidence for autism-Tylenol link. www.nature.com/articles/d41...

FEBS Press Although publication in scholarly peer-reviewed journals remains the gold standard for communication of findings in the life sciences, the gold has been debased by various impurities. Here, I discuss...

Five problems plaguing publishing in the life sciences—and one common cause - Wright - 2024 - FEBS Letters - Wiley Online Library febs.onlinelibrary.wiley.com/doi/10.1002/...