- We performed the first detailed analysis of semi-tryptic peptides and identified organ-specific cleavage motifs.
- Our findings stress the importance of considering post-mortem effects in proteomics studies to avoid bias and incorrect conclusions.

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- Post-mortem protein changes are organ-specific, with significant differences in the number of differentially abundant proteins.
- While overall changes in the heart are minimal, subcellular compartmentalization is disrupted within just 2 hours post-mortem.

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A multi-tissue longitudinal proteomics study to evaluate the suitability of post-mortem samples for pathophysiological research - Communications Biology Longitudinal proteomics study identifies variability in proteome alterations in different tissues, reveals distinct consensus semitryptic motives in different organs and provides criteria for designin...

I am excited to share our latest paper on post-mortem multi-organ protein changes in a clinically relevant mouse model! www.nature.com/articles/s42...

A huge shoutout to my amazing co-authors for their incredible contributions!

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