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Petra Levin

@redrockcity

Microbiologist, mom, runner w/delusions of completing a marathon. Dog enthusiast. This Week in Microbiology (https://www.microbe.tv/twim/).

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23.10.2023
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Latest posts by Petra Levin @redrockcity

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πŸ“’ Postdoc position: Biochemistry & Bacterial cell biology

in our group at Marburg University, Germany, funded by the ERC Advanced Grant "C-SWITCH"

πŸ”—More information at shorturl.at/OlvlL
πŸ“…Deadline: Nov 30, 2025

Please repost. #Postdoc

10.11.2025 18:15 πŸ‘ 29 πŸ” 31 πŸ’¬ 1 πŸ“Œ 1
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A unique inhibitor conformation selectively targets the DNA polymerase PolC of Gram-positive priority pathogens - Nature Communications In this work, Urem et al. characterize the mode of action as well as mechanism of reduced susceptibility related to a class of antimicrobials that is in development for the treatment of infections wit...

🚨 Publication alert! We are stoked to report the structural basis for activity of a novel class of antimicrobials targeting Gram positive priority pathogens in @natcomms.nature.com. There is something for everyone on this paper, and I will highlight a few things below πŸ‘‡ 1/9 doi.org/10.1038/s414...

06.11.2025 10:29 πŸ‘ 36 πŸ” 18 πŸ’¬ 2 πŸ“Œ 1

Any conversation with @markowenmartin.bsky.social is a fun conversation. Really enjoyed sharing our science and my messy whiteboard! Come for a discussion of the environment and antibiotic resistance, stay for a (somewhat tortured) comparison of biology education to learning a foreign language. πŸ’œ

18.10.2025 12:50 πŸ‘ 9 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

πŸ’œ Now that I am a PI I do none of those things too πŸ™ƒ (Except for streaking coloniesβ€”sometimes just for fun!).

18.10.2025 12:45 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Finally out, such an awesome piece of work, very proud of this one: www.cell.com/cell-systems... #MicroSky

04.10.2025 08:48 πŸ‘ 62 πŸ” 27 πŸ’¬ 2 πŸ“Œ 1
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Technician III - Department of Microbiology Position Summary This position will be in the lab of Dr. Joseph E. Peters in the Department of Microbiology. Research in the Peters’ lab broadly involves deciphering mechanisms in genome stability and...

The Peters lab is looking for a new team member! The role transposons play in evolution, basic mechanisms regulating transposition, and applying transposons as tools for genome modification with a special focus on guide RNA-directed transposition. cornell.wd1.myworkdayjobs.com/CornellCaree...

03.10.2025 13:01 πŸ‘ 27 πŸ” 21 πŸ’¬ 2 πŸ“Œ 0
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Localized glutamine leakage drives the spatial structure of root microbial colonization Plant roots release exudates to encourage microbiome assembly, which influences the function and stress resilience of plants. How specific exudates drive spatial colonization patterns remains largely ...

Amazing work by @hueihsuantsai.bsky.social and colleagues from @nikogeldner.bsky.social, Feng Zhou @tonnigrubeandersen.bsky.social labs in Science

Localized glutamine leakage drives the spatial structure of root microbial colonization

www.science.org/doi/10.1126/...

#chemotaxis #MicroSky

03.10.2025 05:55 πŸ‘ 20 πŸ” 10 πŸ’¬ 0 πŸ“Œ 2
Assistant Professor - Tenure Track Faculty The Department of Molecular Biology and Biochemistry at Rutgers, The State University of New Jersey, is inviting applicants for a tenure-track Assistant Professor position. The position requires a doc...

Despite These Times...my department is hiring! I really like my department, we have a good mix of disciplines and organisms and we're really low-drama. We also get pizza at faculty meeting. So if you're a computational and structural biologist, join us! πŸ§ͺ jobs.rutgers.edu/postings/260...

01.10.2025 19:35 πŸ‘ 102 πŸ” 90 πŸ’¬ 3 πŸ“Œ 3

#MicroSky

01.10.2025 15:30 πŸ‘ 3 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
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Population-Level Effectiveness and Herd Protection 17 Years After HPV Vaccine This cross-sectional study investigates population-level effectiveness and herd protection in the first 17 years after human papillomavirus (HPV) vaccination among adolescent girls and young women at ...

This is a truly remarkable finding: 17 years after introduction of the HPV vaccine, there was a decreased prevalence of HPV infection (and therefore decreased cancer risk) in both vaccinated AND unvaccinated individuals. Cancer prevention through herd immunity!!!

30.09.2025 12:59 πŸ‘ 314 πŸ” 111 πŸ’¬ 5 πŸ“Œ 2

Rain >>>>> super hot. Fact.

27.09.2025 20:02 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Let me add one of my favorites: the simple test for toxoplasmosis that's saved so many babies

I knew about the test b/c of my pregnancy & then I happened to rent the house across the street from the man who discovered it & created the modern treatment protocol

med.stanford.edu/news/all-new...

27.09.2025 16:48 πŸ‘ 11 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
Tenure-track Position in Biophysics at Carnegie Mellon University, Department of Physics

Location: Pittsburgh, PA
Open Date: Sep 19, 2025

Description
The Department of Physics at Carnegie Mellon University invites applications for a tenure-track faculty position in biophysics. The appointment is intended to be at the Assistant Professor level, but exceptional candidates at a higher level may also be considered. We seek outstanding candidates with a strong record in cellular and subcellular biophysics. Topics of particular interest include, but are not limited to, uncovering how key characteristics of living systems arise from the interplay between supramolecular cellular structures, how the emergent cellular circuitry defines goals and enables robust decision making, and how metabolic resources are allocated. This encompasses understanding of how information is learned, stored, transduced, and processed across subcellular structures. Applicants with theoretical, data science, or experimental backgrounds within biological physics are encouraged to apply. The ideal candidate will strengthen and extend research programs of current biophysics faculty in the Department of Physics and collaborate with broader life science activities across many departments at CMU and the wider Pittsburgh area.

More details on Interfolio: https://apply.interfolio.com/174360

Tenure-track Position in Biophysics at Carnegie Mellon University, Department of Physics Location: Pittsburgh, PA Open Date: Sep 19, 2025 Description The Department of Physics at Carnegie Mellon University invites applications for a tenure-track faculty position in biophysics. The appointment is intended to be at the Assistant Professor level, but exceptional candidates at a higher level may also be considered. We seek outstanding candidates with a strong record in cellular and subcellular biophysics. Topics of particular interest include, but are not limited to, uncovering how key characteristics of living systems arise from the interplay between supramolecular cellular structures, how the emergent cellular circuitry defines goals and enables robust decision making, and how metabolic resources are allocated. This encompasses understanding of how information is learned, stored, transduced, and processed across subcellular structures. Applicants with theoretical, data science, or experimental backgrounds within biological physics are encouraged to apply. The ideal candidate will strengthen and extend research programs of current biophysics faculty in the Department of Physics and collaborate with broader life science activities across many departments at CMU and the wider Pittsburgh area. More details on Interfolio: https://apply.interfolio.com/174360

I am super excited to announce that we have a tenure-track faculty position in biophysics open in the Department of Physics at Carnegie Mellon! πŸ§ͺ

Interfolio link: apply.interfolio.com/174360

PLEASE, share widely across the blue skies!

Let me briefly explain what we're looking for:

1/10

26.09.2025 15:35 πŸ‘ 102 πŸ” 88 πŸ’¬ 2 πŸ“Œ 5
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Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols.
Thread 1/n

25.09.2025 21:28 πŸ‘ 299 πŸ” 154 πŸ’¬ 14 πŸ“Œ 8
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New in JB: Ma, Wang & Li review the role of DNA methylation in regulating pathogenesis, drug resistance, biofilm formation, adhesion, and motility and more!
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology

25.09.2025 23:00 πŸ‘ 4 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
 A very large brown bear walking in a field of grass.

A very large brown bear walking in a field of grass.

It is Fat Bear Week in Alaska. The popular competition lets anyone vote on which of the animals is most prepared for winter. nyti.ms/3IBbucx

23.09.2025 18:10 πŸ‘ 982 πŸ” 156 πŸ’¬ 38 πŸ“Œ 36

Longstanding collaboration with Scott Manalis where we have developed technology to measure single cell growth rates of bacteria in native seawater with some very surprising results.
www.biorxiv.org/content/10.1...

11.08.2025 16:56 πŸ‘ 11 πŸ” 11 πŸ’¬ 0 πŸ“Œ 0

Very nice writeup on someone I've admired and learned from for many years. I didn't know he had passed until catching up on This Week in Microbiology driving to campus this morning. His 1958 paper on Salmonella growth rates basically founded the formal study of microbial physiology, which...

12.09.2025 13:46 πŸ‘ 12 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
The Fine Structure of the Gene on JSTOR Seymour Benzer, The Fine Structure of the Gene, Scientific American, Vol. 206, No. 1 (January 1962), pp. 70-87

For those interested in further reading, the studies establishing the triplet nature of the genetic code were also reviewed by both Benzer and Crick in two 1962 Scientific American articles -- both worth a read!
www.jstor.org/stable/24937...
www.jstor.org/stable/24936...

12.09.2025 17:50 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Agar art: Microbes make the world go ground.

Agar art: Microbes make the world go ground.

The 2025 agar art contest is open and accepting submissions until Oct. 26! The theme is β€œMicrobes Make the World Go Round.” Submit your artwork and showcase the vital role microbes play in our daily lives. All are welcome to apply! See contest details: asm.org/events/asm-a...

12.09.2025 17:21 πŸ‘ 14 πŸ” 13 πŸ’¬ 1 πŸ“Œ 0
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Rich Losick’s Farewell Publication Reexamines a Molecular Biology Milestone - Harvard University - Department of Molecular & Cellular Biology Richard Losick, Maria Moors Cabot Professor of Biology, Emeritus in Harvard’s Department of Molecular and Cellular Biology, is about to publish what he describes as his β€œlast paper”—though […]

Article about the article from his longtime home, @harvardmcb.bsky.social

www.mcb.harvard.edu/department/n...

12.09.2025 15:53 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
General Nature of the Genetic Code for Proteins - Nature Nature - General Nature of the Genetic Code for Proteins

Original publication here

www.nature.com/articles/192...

12.09.2025 15:53 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Revisiting a Breathtaking Publication in the History of Molecular Biology

The last publication (he says!) from Rich Losick, my PhD advisor.

Historical in nature it focuses on a seminal paper in molecular biology, the study revealing the genetic code to be triplet in nature. Come for the science, appreciate the clear prose!

www.sciencedirect.com/science/arti...

12.09.2025 15:53 πŸ‘ 30 πŸ” 9 πŸ’¬ 2 πŸ“Œ 0
Immunization with peptide encapsulated within synthetic spores activates T cell responses and reduces tumor growth | mBio Effective delivery of antigens to the immune system is essential for activating the adaptive immune system. Synthetic Spore Husk-Encased Lipids (SSHELs) are synthetic bacterial spore-like particles, w...

Immunization with peptides can elicit antigen-specific T cell responses, but they're not widely used because they are poorly immunogenic and are rapidly cleared. Domenico D'Atri solves this by using our "SSHEL" platform (synthetic bacterial spores) .
journals.asm.org/doi/10.1128/...

12.09.2025 14:19 πŸ‘ 14 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0
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Assistant Professor - Molecular Biosciences Department Name / Number: Molecular Biosciences / 0-1210-000 College: College of Arts and Sciences Hiring Salary: Negotiable Appointment Start Date: August 7, 2026 The Department of Molecular Bioscien...

We are hiring! Please share the news.

Tenure Track Assistant Professor in Bacterial Pathogenesis

See link below for details.

We are a vibrantly growing department with friendly colleagues and supportive environment. Bonus: year-round sunshine in Tampa, FL 🌀🌴

Job Ad: tinyurl.com/USF-Microbio...

12.09.2025 13:53 πŸ‘ 10 πŸ” 11 πŸ’¬ 0 πŸ“Œ 0

Should have noted we called her β€œMama Shapiro” in Rich’s lab…

11.09.2025 23:44 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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FranΓ§ois Jacob (1920–2013) The French Nobel laureate ushered in the field of molecular genetics by defining the regulated cellular pathway that translates DNA into proteins.

I also enjoy their tribute to a hero of bacteriology, Francois Jacob.

www.science.org/doi/10.1126/...

11.09.2025 22:33 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Changing Views on the Nature of the Bacterial Cell: from Biochemistry to Cytology | Journal of Bacteriology When the authors were graduate students in the 1960s, the bacterial cell was generally viewed as an amorphous vessel housing a homogeneous solution of proteins. Trained as biochemists, we would break ...

I, of course, am also very fond of the many retrospective reviews she wrote with Rich. This one on the advent of bacterial cell biology and its impact is great.

journals.asm.org/doi/10.1128/...

11.09.2025 22:33 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
A Half Century Defining the Logic of Cellular Life | Annual Reviews Over more than fifty years, I have studied how the logic that controls and integrates cell function is built into the dynamic architecture of living cells. I worked with a succession of exceptionally ...

This is a lovely article she wrote describing the arc of her career if people want to appreciate not only her work but also her beautiful prose. www.annualreviews.org/content/jour...

11.09.2025 22:33 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Along with Rich Losick, my PhD advisor, Lucy pioneered the use of bacteria for the study of development and it was work in her lab and Rich’s that changed our view of bacteria from β€œbags of enzymes” to that of highly organized cells as intricately constructed as those from an eukaryote.

11.09.2025 22:33 πŸ‘ 4 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0