Luis Orellana (Coto)'s Avatar

Luis Orellana (Coto)

@cotoorellana

Microbial Ecology and Evolution | Investigating microbes through the eyes of ones and zeros Group Leader @ Max Planck Institute for Marine Microbiology πŸ‡¨πŸ‡±β†’πŸ‡ΊπŸ‡Έβ†’πŸ‡©πŸ‡ͺ #Fulbright #ERCStG

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19.10.2023
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Latest posts by Luis Orellana (Coto) @cotoorellana

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GitHub - bluenote-1577/savont: Amplicon sequencing variants from 16s ONT R10.4 / HiFi long reads Amplicon sequencing variants from 16s ONT R10.4 / HiFi long reads - bluenote-1577/savont

Announcing a new tool for "denoising" long-read amplicon sequences: savont.

Savont enables amplicon sequence variants (ASVs) directly from nanopore (or HiFi) long reads. Tested on 16S nanopore amplicons -- seems to work okay.

1/4

github.com/bluenote-157...

28.01.2026 18:45 πŸ‘ 51 πŸ” 28 πŸ’¬ 1 πŸ“Œ 2
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We just released #anvio v9, "eunice" πŸŽ‰

This version represents over 2,000 changes in the codebase since v8, increasing the total number of programs in the anvi'o ecosystem to 176.

Read the release notes:

github.com/merenlab/anv...

Visit our up-to-date web page:

anvio.org

20.01.2026 11:48 πŸ‘ 71 πŸ” 34 πŸ’¬ 2 πŸ“Œ 3
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Troubleshooting common errors in assemblies of long-read metagenomes - Nature Biotechnology Long-read sequence assemblies from metagenomes contain frequent errors.

Troubleshooting common errors in assemblies of long-read metagenomes - @merenbey.bsky.social @banfieldlab.bsky.social go.nature.com/44P7nSm

02.01.2026 16:39 πŸ‘ 43 πŸ” 20 πŸ’¬ 0 πŸ“Œ 2
SALTO Symposium about specialized bacteria

A short article:
www.mpi-bremen.de/en/SALTO-Sym...
Photo credits: Β© Fanni Aspetsberger/Max Planck Institute for Marine Microbiology

18.12.2025 07:50 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
SALTO Symposium about specialized bacteria

This symposium took place within the framework of the SALTO program, a collaboration between the Max Planck Society (MPG) and the Centre national de la recherche scientifique (CNRS). We're grateful to everyone who made this event possible.

18.12.2025 07:50 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Looking back at a highlight from 2025: Great energy at the 2025 SALTO Symposium we organized at the MPI for Marine Microbiology! Researchers from Germany, France, Spain, Portugal, and Australia joined us in Bremen to explore the evolutionary links between specialized bacteria and their algal hosts.

18.12.2025 07:50 πŸ‘ 3 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

πŸŽ‰ The #SeqCode has reached a significant milestone: with the validation of the genus Skiveiella, a total of 1,000 #names have now been validly published under the SeqCode.

This achievement marks a major step forward in the adoption and impact of the SeqCode within the scientific community.

13.12.2025 06:11 πŸ‘ 11 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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A high-resolution diel survey of surface ocean metagenomes, metatranscriptomes, and transfer RNA transcripts - Scientific Data Scientific Data - A high-resolution diel survey of surface ocean metagenomes, metatranscriptomes, and transfer RNA transcripts

Our data descriptor that includes surface ocean metagenomes (with Illumina & PacBio), metatranscriptomes, and tRNAs transcripts from HawaiΚ»i is now out:

www.nature.com/articles/s41...

Just so you don't have to wait for our own investigations to finish. More data are here:

merenlab.org/data/hads/

05.12.2025 09:03 πŸ‘ 17 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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πŸ”Š APPLY NOW for our #MarMic #MSc/#PhD program!

Come to #Bremen and take an interdisciplinary approach to #marine #microbiology, #molecularbiology, #biochemistry, #evolution and more.

⏳ Open until Feb 28 2026
➑ marmic.mpg.de

#graduatestudents #marinescience #sciencecareer #IMPRS @maxplanck.de

02.12.2025 13:47 πŸ‘ 14 πŸ” 16 πŸ’¬ 1 πŸ“Œ 1

Don’t miss this amazing opportunity to join Miguel's group in Denmark!

24.11.2025 21:02 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Probiotic Engraftment of Akkermansia muciniphila in an In Vitro Synthetic Microbial Community - Microbial Ecology Akkermansia muciniphila is a specialist mucin glycan-degrader that is common in the human gut. A. muciniphila is associated with host health and therefore proposed as a next-generation probiotic. Howe...

Akkermansia muciniphila has potential as a next-generation #probiotic, but can it claim a niche and persist in a pre-existing, complex microbial community (in vitro)? πŸ¦ πŸ”

#microsky
#microbiomesky
#glycotime

link.springer.com/article/10.1...

20.11.2025 11:27 πŸ‘ 20 πŸ” 5 πŸ’¬ 2 πŸ“Œ 0

I knew early on I wanted to work with computers, but because of dyslexia I ended up in a lower-tier German school. The career office said a tech job wasn’t realistic. I ignored that, took a convoluted path into university, discovered bioinformatics, got hooked on algorithms&proteins, and became a PI

24.11.2025 02:41 πŸ‘ 80 πŸ” 7 πŸ’¬ 2 πŸ“Œ 0

🫣

20.11.2025 19:19 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

πŸ‘‹ @cotoorellana.bsky.social

17.11.2025 11:55 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

SingleM v0.20.2 - ONT/PacBio input reads now supported (if somewhat inefficiently), plus improved Lyrebird database for phage profiling.

Microbial fraction is now prokaryotic fraction, easier to specify input genomes.

17.11.2025 04:49 πŸ‘ 18 πŸ” 6 πŸ’¬ 2 πŸ“Œ 1
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ECR connection: Meet Meren when you need to A means for ECRs to get advice from a senior scientist outside of their support network

Starting this week, I set aside one hour each week to meet ECRs outside my group who want to discuss career development, mentorship, or any non-technical professional questions.

Here is a blog that explains my motivation for this and how to schedule a meeting:

merenlab.org/2025/11/16/E...

16.11.2025 16:56 πŸ‘ 52 πŸ” 29 πŸ’¬ 1 πŸ“Œ 0

Excellent work from @aroneys.bsky.social here. Free to read version at rdcu.be/ePJp4

13.11.2025 11:12 πŸ‘ 20 πŸ” 4 πŸ’¬ 0 πŸ“Œ 1
Average nucleotide identity β€” the backbone of modern ecological genomics Nature Reviews Genetics, Published online: 30 October 2025; doi:10.1038/s41576-025-00911-5In this Journal Club, Luis Orellana recalls a 2005 publication by Konstantinidis and Tiedje that introduced average nucleotide identity as a sequence-based metric to determine the relatedness between two genomes, which helped to operationally define bacterial species.

ICYMI: New online! Average nucleotide identity β€” the backbone of modern ecological genomics

06.11.2025 14:29 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Good luck! :)

05.11.2025 09:12 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Average nucleotide identity β€” the backbone of modern ecological genomics Nature Reviews Genetics, Published online: 30 October 2025; doi:10.1038/s41576-025-00911-5In this Journal Club, Luis Orellana recalls a 2005 publication by Konstantinidis and Tiedje that introduced average nucleotide identity as a sequence-based metric to determine the relatedness between two genomes, which helped to operationally define bacterial species.

New online! Average nucleotide identity β€” the backbone of modern ecological genomics

30.10.2025 14:28 πŸ‘ 10 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Average nucleotide identity β€” the backbone of modern ecological genomics - Nature Reviews Genetics In this Journal Club, Luis Orellana recalls a 2005 publication by Konstantinidis and Tiedje that introduced average nucleotide identity as a sequence-based metric to determine the relatedness between ...

The average nucleotide identity (ANI) underpins how we map microbial diversity, compare species, and connect genomes to ecology.
I wrote a short piece reflecting on the discovery and significance of this metric (and really enjoyed digging into the context and story behind it!) #microsky 🧬

30.10.2025 21:11 πŸ‘ 58 πŸ” 22 πŸ’¬ 1 πŸ“Œ 2

We are live from Bremen! #microsky

08.10.2025 17:51 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Two full-time positions | Bioinformatician (m/f/d) + Applications Specialist (m/f/d) - Molecular Biology The Genome Facility at the Max Planck Institute for Evolutionary Biology in PlΓΆn is seeking to fill two positions (full time) to support and expand our core facility services.

Two new positions are available at the MPI for Evolutionary Biology to support development of our genomics facility. Both stand to become permanent. Both offer a ton of opportunity to engage in a wide range of creative science.

Pls repost πŸ™

www.evolbio.mpg.de/3838377/job_...

06.10.2025 11:16 πŸ‘ 20 πŸ” 31 πŸ’¬ 0 πŸ“Œ 0
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StrucΒ­tures of methΒ­ane-acΒ­tivΒ­atΒ­ing enΒ­zyme in eluΒ­sive arΒ­chaea

@mariecmueller.bsky.social @cuwelte.bsky.social @mpimarinemicrobio.bsky.social

#methane #ANME #archaea #MCR #microbiology #biochemistry #StructuralBiology

mpi-bremen.de/en/Structure...

09.09.2025 11:32 πŸ‘ 39 πŸ” 13 πŸ’¬ 2 πŸ“Œ 3
Group photo of postdocs conducting research at a Max Planck Institute

Group photo of postdocs conducting research at a Max Planck Institute

The #MaxPlanckPostdocProgram offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops. The call for applications is open now! πŸš€ Take advantage of this opportunity and browse the job vacancies. www.mpg.de/en/max-planc...

01.09.2025 08:46 πŸ‘ 113 πŸ” 99 πŸ’¬ 2 πŸ“Œ 3

I'm very happy to share that our paper describing the evolution of sex chromosomes in brown algae is out!πŸŽ‰ This project was a long journey, but it came together into a nice story 🧬 🌊 Grateful to everyone who helped along the way!

29.08.2025 05:38 πŸ‘ 29 πŸ” 12 πŸ’¬ 1 πŸ“Œ 0
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GitHub - wwood/CoverM: Read alignment statistics for metagenomics Read alignment statistics for metagenomics. Contribute to wwood/CoverM development by creating an account on GitHub.

Maybe playing with some of the statistics in CoverM (github.com/wwood/CoverM) could help you get a quick answer

21.08.2025 09:28 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Hola! agrΓ©game porfa! :)

19.08.2025 06:34 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Sulfoquinovose is a select nutrient of prominent bacteria and a source of hydrogen sulfide in the human gut - The ISME Journal The ISME Journal - Sulfoquinovose is a select nutrient of prominent bacteria and a source of hydrogen sulfide in the human gut

You know sulfoquinovose (SQ)?

No?!

You should if you are interested in diet-gut microbiome 🦠🧫interactions πŸ˜‰

SQ is a sulfosugar that this part of a ubiquitous sulfonolipid in photosynthetic organisms and thus part of your diet - if you like leafy greens and algae πŸ₯¬

www.nature.com/articles/s41...

07.08.2025 13:49 πŸ‘ 10 πŸ” 7 πŸ’¬ 1 πŸ“Œ 1
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A practical guide on environmental genomics for prokaryotic systematics Environmental shotgun sequencing can provide great insight into microbial community profiles, functional capabilities, and the recovery of metagenome-…

Happy to share our Practical Guide on Environmental Genomics for Prokaryotic Nomenclature, led by @nathanernster.bsky.social and part of SAM's special issue on @seqcode.bsky.social

www.sciencedirect.com/science/arti...

05.08.2025 13:47 πŸ‘ 10 πŸ” 5 πŸ’¬ 0 πŸ“Œ 1