Cristina C Clement MS PhD

US HUPO 2026 in Saint Louis, Missouri, this February 20-24th was, as always, an amazing science show!

HUPO2025, November 9-13th in Toronto, Canada! Mission accomplished! Making new connections in proteomics and related omics technologies, opening new avenues for my future research in immunoproteomics, clinical proteomics, and cellular omics to better understand signal transduction!

I presented some of my last research data on Trp metabolites with immunosuppressive activities in the Chemical Biology & Biochemistry session at the ACS National Meeting in August 2025. ACS society is an excellent avenue for networking and making new scientific connections in any chemistry field.

Great memories from our departmental group photo in the Belfer Building at Weill Cornell Medicine, in Manhattan, NYC, this September 2025!

ASMS 2025 in Baltimore, MA, USA (June 1st-5th) was a great opportunity to share my own developed and optimized proteomics platforms highlighting the cellular signaling in human dendritic cells. Thanks to all ASMS experts for their training workshops in mass spectrometry and bioinformatics analysis!

asms-proceedings-prod.s3.amazonaws.com/303/3373/325...

It was a great scientific meeting this last AAI (American Association of Immunologists, May 2nd-7th, Honolulu, Hawai'i). Our lab, PI: Professor Laura Santambrogio (on my right in the photo) was chosen for a talk on one of my major projects, pharmacology of 3-HKA. Waikiki beach was a nice gift.

There was a "French Connection" before I immigrated and settled to USA in 1995. I gained an award from EU to study at Pasteur Institute: Jan-March 1994: trained in the experimental and theoretical field of "Proteins: Structure and Function": Director: Dr. Michel Goldberg (me#6 in the group photo).

The "Golden Age" of my postdoctoral experience, Associate Faculty and Research Assistant Professor at Albert Einstein College of Medicine, in the lab of Dr Laura Santambrogio (2007-2019): system biology of antigen processing and presentation on MHC-II, immunopharmacology and immunopeptidomics.

The "Golden Age" of my postdoctoral experience: Albert Einstein CM (2007-20010). Promoted to Associate Faculty (2010-2012) and Research Assistant Professor (2012-2019), before moving to WCM: Dr Laura Santambrogio lab: immunoproteomics, immunopeptidomics; immunopharmacology and immune signaling.

I have been trained in biochemistry, cell biology and protein chemistry at UMKC (1995-1998); awarded MS in Dec 1998, securing my acceptance to the PhD Biochemistry CUNY. I always had my bench; shown here in my first lab for PhD training: Dr. William T Morgan (far-right second photo from the left).

Highlighted at the left: My first students from the Biochemistry Lab developed with Dr Maria Tomasz at Hunter College (200-2001).

Crystallization and preliminary crystallographic characterization of three peptidic inhibitors in complex with α-thrombin - PubMed The serine protease thrombin plays a major role in thrombosis and haemostasis. This has driven interest in thrombin inhibitors as potential antithrombotic drugs. Here, the crystallization and prelimin...

Other papers related to my SBDD designed peptidic inhibitors of thrombin:
pubmed.ncbi.nlm.nih.gov/21206024/
link.springer.com/chapter/10.1...
link.springer.com/chapter/10.1...
www.5z.com/24APS/24APS....

2006 –2019: Adjunct Assistant Professor in the Chemistry Department, Lehman College (CUNY). Lecturer for the general chemistry, organic chemistry and advanced biochemistry courses and lab instructor for the same disciplines. Develop my own syllabi for the analytical and biochemistry courses.

I paid my tuition from my salary as an Adjunct Lecturer in the Chemistry Department, during my PhD work in Biochemistry: first at City College (1998-2000), Hunter College (2000-2002) and Lehman College (2002-2006) of CUNY. Shown: my undergraduate students in Biochemistry and Dr. Manfred Philipp.

And these were the days I was working for the 2nd subject of my PhD (left: Dr. Manfred Philipp lab, Lehman College CUNY) (FMOC peptide synthesis and thrombin inhibitors); the second postdoc at Albert Einstein CM: trained to perform mass spec-based proteomics-my first analysis on LTQ, MALDI (right).

The postdoctoral years: 2005-2007: Sloan Kettering, Dr. Gabriela Chiosis lab (discovery of pharmacological scaffolds for small molecules inhibitors of Hsp-70/Hsp-90 using molecular docking, biophysics, and cell-based assays. 2007-2010: Albert Einstein College of Medicine, Dr Laura Santambrogio Lab.

DNA adduct of the mitomycin C metabolite 2,7-diaminomitosene is a nontoxic and nonmutagenic DNA lesion in vitro and in vivo - PubMed Mitomycin C (MC) is a cytotoxic and mutagenic antitumor agent that alkylates and cross-links DNA. These effects are dependent on reductive bioactivation of MC. 2,7-Diaminomitosene (2,7-DAM) is the maj...

papers published before being awarded PhD: shared 1st author and co-author:
pubmed.ncbi.nlm.nih.gov/15720125/
pubmed.ncbi.nlm.nih.gov/11523988/
papers published after PhD on DTI X-Ray structure and biochemical evaluation of their anticoagulant activities:
pubmed.ncbi.nlm.nih.gov/22457833/

The Graduation Day: May 2006. PhD Biochemistry from the Graduate Center of CUNY (GCCUNY): from left to right: Dr Elise Champeil, Dr. Sweta Ladwa (both postdocs in the Dr. Maria Tomasz lab, at Hunter College) and the Executive Officer, Biochemistry Department: Dr Lesley Davenport (Brooklyn College).

Me and the award for qualifying to the top 10 speakers at the Young Investigator Award at American Peptide Society (2009).

My seminar at the Pathology retreat at Albert Einstein College in 2009. A photograph from the lab of Dr Laura Santambrogio at Albert Einstein College (around 2015).

My second postdoctoral research appointment at Albert Einstein College of Medicine (2007-2019; promoted to Associate Faculty and Research Assistant professor): development and optimization of mass spectrometric (MS) based assays for global and targeted immunoproteomics and immunopeptidomes analysis.

Sloan Kettering Institute (SKI): 2005-2007: developing cell-based assay for studying drugs effects upon the proliferation of different cancer lines (breast and small lung carcinoma.

Dr. Maria Tomasz lab: Hunter College, Manhattan, 1999-2006: analysis of DNA adducts derivatized with anticancer drugs and DNA translesion synthesis using high resolution DNA sequencing gels. Columbia U., NYC-Spring 2005: Prof Wayne Hendrickson class in X-Ray.

The way we were during the famous decade 1998-2008 at Hunter College of CUNY, attending classes in structural biology at Columbia University (my PH times 1998-2006); and my first postdoctoral position at Sloan Kettering (2005-2007).

Gordon Conference on "DNA and Mutagenesis"-Ventura, California 2005: poster presentation on DNA translesion synthesis.
Dr. Maria Tomasz lab: Hunter College, Lexington Avenue, Manhattan, 1999-2006: HPLC (high pressure liquid chromatography) analysis of DNA adducts derivatized with anticancer drugs.

Me (middle in black) and some of my students from Biochemistry lab class developed at Hunter College-CUNY, NYC in 2000-2001.

Gordon Conference on "DNA and Mutagenesis"-Ventura, California 2005: poster presentation on DNA translesion synthesis.

Dr. Maria Tomasz lab: Hunter College, Lexington Avenue, Manhattan, 1999-2006: HPLC (high pressure liquid chromatography) analysis of DNA adducts derivatized with anticancer drugs.

Dr. Maria Tomasz lab: Hunter College, Lexington Avenue, Manhattan, 1999-2006: HPLC (high pressure liquid chromatography) analysis of DNA adducts derivatized with anticancer drugs.

I saw many science conferences where the awardees are sharing memories from their times when they were students, so I decided to do the same using this media platform as I used to do also on Twitter (X). Some memories shared here were not yet disclosed on other social media accounts!

My seminar on proteomics and immunopeptidomics of murine dendritic cells at HUPO in Cancun December 2022 and the invited seminar at PEAKS (Bioinformatics solutions) user's zoom meeting.

The emerald shining lights of Empire State during Saint Patrick's Day in Manhattan NYC.

A view of the beach in front of The Scripps Seaside Forum where the Peptide Therapeutics Symposium takes place each year in October.