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Tim

@timisstuck

Executive Editor at Life Science Alliance. I help decide how biology thinks πŸ€” Views are my own and do not reflect editorial policy. www.timfessenden.com

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09.11.2023
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Latest posts by Tim @timisstuck

Thanks for sharing Richard! You can see why I wanted to quote you here.

03.03.2026 18:41 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Really cool work here!! Congrats @emery-lab.bsky.social

03.03.2026 17:18 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Negative Data LSAΒ is proud to be a home for studies that report negative or inconclusive results, serving our mission of lowering barriers to publication for rigorous findings of immediate value to the field. The a...

Editorial here:
www.life-science-alliance.org/content/9/3/...

And peruse some fantastic studies reporting negative results, including important refutations, here:
www.life-science-alliance.org/content/nega...

02.03.2026 17:49 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1
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Editorial by me, in our March issue!

Negative results are a thorny issue in essentially all fields of scientific research, and deserve a renewed look by authors and editors πŸ‘‡

02.03.2026 17:48 πŸ‘ 1 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
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It’s finally out! Together with @embopress.org and
@reviewcommons.org, we conducted a structured side-by-side comparison of human peer review and our AI scientific review (see thread πŸ‘‡πŸ‘‡πŸ‘‡πŸ”₯).

26.02.2026 14:34 πŸ‘ 77 πŸ” 38 πŸ’¬ 2 πŸ“Œ 4
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Returning to this to emphasize that NIH action/inaction is preventing funds from getting to researchers. Important to note the difference between legislative budget actions and executive disbursement actions. graph via @deniswirtz.bsky.social

27.02.2026 15:49 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Required reading, folks πŸ‘‡

27.02.2026 15:46 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

πŸŽ‰πŸŽ‰πŸŽ‰

26.02.2026 13:22 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Preview
CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly - Nature CRISPR–Cas9 screening identifies CLCC1 as a factor that increases neutral lipid flux to prevent hepatic steatosis and promotes nuclear pore complex assembly by promoting membrane bending and fusi...

Sooo happy to share our new paper in @nature.com β€œCLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly.” A terrific collaboration with @arrudalab.bsky.social, led by co–first authors Alyssa Mathiowetz and Emily Maymand.
www.nature.com/articles/s41...

25.02.2026 18:11 πŸ‘ 83 πŸ” 34 πŸ’¬ 6 πŸ“Œ 4
Preview
Actin waves guide an outward movement of microclusters in the lymphocyte immunological synapse - EMBO Reports The lymphocyte immune response begins with antigen recognition on antigen-presenting cells, leading to the formation of the immunological synapseβ€”a specialized interface for biochemical and biophysica...

doi.org/10.1038/s443...

20.02.2026 19:00 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Congrats @sudha-kumari.bsky.social on this nice paper out in @emboreports.org πŸ₯³

20.02.2026 19:00 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

This is also something that NIH Director Bhattacharya loves to trumpet (as if no other NIH officials before him recognized this problem...)

20.02.2026 13:17 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Yes absolutely

20.02.2026 03:38 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

It seems republicans under Trump are continuing this trend? Overall increased NIH budget and very minor cuts to NSF and CDC.

But of course that does not account for grant awards delayed or prior grants cancelled by the current HHS/NIH...

19.02.2026 16:08 πŸ‘ 0 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0
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19.02.2026 14:44 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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!!!

www.theatlantic.com/ideas/2026/0...

19.02.2026 14:43 πŸ‘ 0 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

One can assume they identified a gap (in topical area/impact factor) in their portfolio. Such a gap is *certainly* not visible from the outside, but they only do this with clear business rationale.

18.02.2026 19:51 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Springer Nature responds to community feedback with its new journal series Nature Progress | Springer Nature Group | Springer Nature Supported by Nature Portfolio’s in-house editorial expertise, Nature Progress journals will expand access to high impact publishing to more

Nature group: "DO YOU WANT MORE JOURNALS???"
Researchers: "um... not... really? no there are alread-"
Nature: "YESSS HERE YOU GO MORE JOURNALSSSS!!"

group.springernature.com/gp/group/med...

@springernature.com

18.02.2026 12:59 πŸ‘ 5 πŸ” 3 πŸ’¬ 2 πŸ“Œ 0
EMBO EMBL Symposium  
Microtubules: from atoms to complex systems
17-20 June 2026
EMBL Heidelberg and Virtual

EMBO EMBL Symposium Microtubules: from atoms to complex systems 17-20 June 2026 EMBL Heidelberg and Virtual

We are pleased to be a media partner for the @embo.org @embl.org Symposium - Microtubules: from atoms to complex systems
Abstract submission: 11 Mar 2026
Registration (On-site): 6 May 2026
Registration (Virtual): 10 Jun 2026

bit.ly/4jDTuMH
#EESMicrotubules

18.02.2026 10:01 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Minor point:
Not defending the publisher and certainly not the authors here, but it is common for the journal to convey the authors’ assertions about the paper, if any.

15.02.2026 21:53 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Thanks Prof Baumelle for the summary of this really exhaustive look at a new post-translational modification of Syk and how it affects phagocytosis!

12.02.2026 17:08 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Super nice work covering stops, starts, and reversals in axonal traffic. Congrats!

12.02.2026 17:07 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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πŸ”¬Join our #ReproductionMS seminar with Dr.
@maikbischoff.bsky.social on "Coiling a Duct: How Mesenchymal Cells Sculpt Male Reproductive Organ Architecture" this Wednesday, 11 February 12pm CET. DM for Zoom details.

09.02.2026 10:22 πŸ‘ 14 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0
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Hello epithelial mechanics fans!! I’m Juanma @juanmagararc.bsky.social πŸ‘‹ I work on cell mechanics (see celldynamicslab.com) and use Flipper-TR FLIM to probe membrane biophysics in cells.

Join me on this tour about Flipper: what it measures, strengths, advice, cool case studies, and cute drawings!

08.02.2026 07:59 πŸ‘ 80 πŸ” 26 πŸ’¬ 3 πŸ“Œ 4
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Let's look at this wikipedia article... ah yes.

06.02.2026 15:00 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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The first person listed under "speakers" is this guy. There is no one at Brown by this name... The homepage link takes you to a wikipedia article about him.

But h index = 137!!

06.02.2026 14:57 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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One of the spammy things you see repeatedly as a journal editor are invitations to publish conference proceedings. They get to have a paper and the targeted journal collects an APC.

Like this one. Is this real? Who knows

06.02.2026 14:52 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

πŸ‘€

06.02.2026 14:48 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Quite! I'm poking around the topic of null results lately and the issue brings one immediately to big/old/fundamental philosophical problems in scientific knowledge production.

05.02.2026 13:22 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

A lesser known quote from Bacon

04.02.2026 20:38 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0