Some thoughts and ideas for keeping your children safe and for conversation starters that may arise with them around the Los Angeles fires, in the coming hours, days and weeks.
climatemama.com/how-to-talk-... #lafires #calfires
An eerie sunrise in LA
#CalFires #Wildfires #LACounty
Unsurprisingly, Mark Zuckerberg allowing users to call gay people "mentally ill" isn’t well received internally – to say the least
BREAKING: State Farm, one of the biggest insurers in California, canceled hundreds of homeowners' policies last summer in Pacific Palisades—the same area which is now being ravaged by a devastating wildfire, per Newsweek.
De source mal informée, dépité par la longueur des négociations, De Wever négocierait le rattachement de la Flandre aux US avec D. Trump.
Ce dernier a confirmé qu'il comptait bien faire de la Flandre un district à facilités du nouvel État américain du Québec.
😇☺️
wow, le traitement du bug de l'an 2000 au JT de la RTBF... quel reportage, on sent une investigation en profondeur ! 🤡
Un drone d'avenir 😥
Remarque pertinente de @jbezivin.bsky.social : Dans dix à vingt ans, le ciel sera rempli de drones de toutes tailles, de 5 cm à 5m et il y en aura partout, villes, campagnes et mer. Par contre il n'y aura plus d'oiseaux. 💀
#OnlineFirst
Bridging MDE and AI: a systematic review of domain-specific languages and model-driven practices in AI software systems engineering
Simon Rädler, Luca Berardinelli, Karolin Winter, Abbas Rahimi & Stefanie Rinderle-Ma
doi.org/10.1007/s102...
#OnlineFirst
Systematizing modeler experience (MX) in model-driven engineering success stories
Reyhaneh Kalantari, Julian Oertel, Joeri Exelmans, Satrio Adi Rukmono, Vasco Amaral, Matthias Tichy, Katharina Juhnke, Jan-Philipp Steghöfer & Silvia Abrahão
doi.org/10.1007/s102...
#OnlineFirst
Human factors in model-driven engineering: future research goals and initiatives for MDE
Grischa Liebel et. al.
doi.org/10.1007/s102...
🌟 Curious minds, help me out! 🧠 I'm diving into **Model Transformation** in Model-Driven Engineering (software engineering). It's abstract & tricky for a beginner—any advice, tips, or resources from those who've been there? 🙏✨ #MDE #SoftwareEngineering #LearningJourney
Model-driven engineering of Cutaneotrichosporon oleaginosus ATCC 20509 for improved microbial oil production https://www.biorxiv.org/content/10.1101/2024.03.19.585731v1
I'm going to try to model the data things I want to see on here.
For introduction, offline I'm a Big Data systems "subject matter expert" (data... strategy, architecture, engineering, analysis, science).
So I'll try posting more insights from our data-driven world.
Open recruitment for the Tornini Lab Department of Integrative Biology and Physiology & Institute for Society and Genetics Hispanic Serving Institution Infrastructure Initiative University of California, Los Angeles (UCLA) www.torninilab.org We are a new developmental, cell, and molecular biology lab interested in understanding the genetics of vertebrate neurodevelopment. We use genome engineering, single-cell technologies, behavioral analyses, pharmacological profiling, confocal imaging, genomics, and computational biology using the vertebrate zebrafish (Danio rerio) system and other models (like sea lamprey) for evolutionary studies. Our work is driven by curiosity, independence and teamwork, fun, a sense of urgency, and a desire to understand how networks of genes regulate brain and organismal development. This work can help us better understand basic mechanisms of what happens in human developmental disorders or diseases and can inform novel therapeutic strategies. We are recruiting across all levels. Our lab works in multiple complementary areas (please see below). We’re looking to match motivated people with what motivates them in a supportive and engaging environment. We are recruiting staff research scientists (1-2 years after undergrad+), graduate students (open rotation positions), postdocs, and other positions as relevant. While multiple of our projects are already funded, we strongly support candidates to identify and apply for your own fellowships/grants with the full mentorship and resources of the lab. Like our research? Think you might be a good fit? Consider joining us! For more information, please visit our website, the next page, or contact Val at: vtornini at ucla dot edu UCLA is an equal opportunity employer.
Novel micropeptides in vertebrate neurodevelopment Using zebrafish models, we ask: what are these proteins; what are their functions in neurodevelopment; what are other “ignored” or “dark proteome” genes we are missing; and what can they reveal about human neurodevelopmental disorders or diseases? Chromatin regulators in vertebrate development and behavior A growing group of evolutionarily conserved chromatin regulators have been identified as genes linked with neurodevelopmental disorders, such as autism. In many cases, patients may struggle with co-occurring conditions that impact daily life in childhood and adulthood, including seizures, sleeplessness or sleep disruptions, and autoimmune disruptions. How do these genes work to establish and maintain neural cell types during development, and in turn shape circuits during early critical periods, including interactions with the environment, to establish organismal physiological processes? Non-neuronal regulation during development and aging Non-neuronal cell types, including oligodendrocytes and microglia, have emerged as key players in shaping neurodevelopment and into adulthood. How are the cellular, molecular, and physiological dynamics of these cell types in developing and aging brains affected in mutant genetic models linked to neurodevelopmental disorders? Can we target these cells to modulate neural dysregulation and resulting behaviors in these mutant models? Evolution of vertebrate brain cell states We seek to understand the principles of how novel genes co-evolve with the emergence of neural cell types found only in vertebrates. We use cross-species genomics and functional approaches with the jawless vertebrate model, sea lamprey, to elucidate the roles of vertebrate-specific genes on the gene regulatory networks. Bioethics, neuroethics, and genetics We seek to integrate evidence-based methods throughout our projects to investigate and address bioethical considerations in this research domain.
We are openly recruiting at all levels at the Tornini Lab at the University of California, Los Angeles (UCLA)!
Please share with your networks. For more information, please check the info below, visit www.torninilab.org, or email me directly at vtornini at ucla dot edu. Thank you in advance!
One year of CHIL infographic Five key themes: - Mental health - Health and care systems - Medicines optimisation - Methods and infrastructure - Infection resilience Collaboration: - 14 active SME/industry partnerships and 22 in development - 14 countries with potential partnerships being explored Grants and research outputs: - 35 active grants - 30 grants submitted and 5 in development - £55m value of research funding portfolio - 106 publications across all CHIL theme leads
December 2023 “All in it together”: University launches Civic Health Innovation Labs (CHIL) The University of Liverpool launched an innovation lab where health and technology experts can work together to drive advances in care and wellbeing. The secure data environment will allow researchers to address local and global health challenges by developing new artificial intelligence (AI) and other data-driven advances. January 2024 CHIL strengthens health innovation collaborations with South Korea We were delighted to welcome Professor Hong-Gee Kim, Seoul National University, to sign a Memorandum of Understanding on behalf of his Biomedical Knowledge Engineering Laboratory (BIKE). February 2024 The Big AI Debate: Who Gets to Decide? The Liverpool City Region Civic Data Cooperative at the University of Liverpool hosted a public debate on public involvement in data and artificial intelligence (AI). March 2024 £4.9m secured to advance public health research The Office for Life Sciences (OLS) has awarded CHIL this significant amount to deliver the ‘Data-Action Accelerator’. This project brings data scientists and engineers working in and around the NHS together with researchers to tackle global problems.
April 2024 Seminar from Prof David Patrick from British Colombia: We welcomed Prof David Patrick, a Infectious Diseases Physician and Epidemiologist from the University of British Columbia to talk about ‘Preventing Childhood Asthma and Allergy: The Neglected Impacts of Antibiotic Stewardship and Human Milk Exposure in Infants’ Healthy Urban Places Award: Funding was announced for an £8m project to create Healthy Urban Spaces in Liverpool and Bradford. The Civic Data Cooperative (CDC) will provide technical expertise to help with the household data linkage of environment data to the cohort. May 2024 Professor Chris Whitty visits CHIL: Professor Whitty, Chief Medical Officer, heard researchers and public advisers present outlines of more than 40 areas of research that are tackling issues that most affect areas of deprivation in the Liverpool City Region. CHIL Director, Professor Iain Buchan also illustrated the work at CHIL to tackle the rising burden of mental health conditions, the pressures on health systems from more people living longer, the rising threat of antimicrobial resistance, and preparation for the next pandemic. Contribution to report commissioned by Wellcome Trust: CHIL Director Prof Iain Buchan contributed to the report ‘Catalytic environments to drive progress in digital mental health research’. June 2024 Delegation from Taiwan: We were delighted to welcome a delegation from the Taiwan Ministry of Health and Welfare to CHIL. Some great conversations exploring civic data science and dynamic biobanks. One of many visits from potential International partners that have taken place through the year. Funding awarded for international study on epilepsy research: Dr Gashirai Mbizvo, an NIHR Academic Clinical Lecturer in Neurology, has received almost £300k for his Emerging Leader Fellowship Award from the Epilepsy Research Institute. This will fund a study on the how people with epilepsy can safely stop taking the drug sodium valproate.
August 2024 Researchers better understand Structured Medication Reviews New paper from Lauren Walker and the DynAIRx (Artificial Intelligence for dynamic prescribing optimisation and care integration in multimorbidity) team – one of CHIL’s programmes. M-RIC’s Public and Patient Involvement launch event September 2024 Count Me In visit to Aintree Racecourse The M-RIC initiative featured a stand at Aintree Racecourse, sharing how the project is making it easier for patients and service users to get involved in research so we can improve future care and treatments. Find out more at http://merseycare.nhs.uk/count-me-in.” October 2024 Playing a key role in Liverpool City Region mission to the US: CHIL Director Professor Iain Buchan played a key role in the Liverpool City Region’s recent mission to the United States to drive trade, investment and tourism. University and Roche formalise partnership to improve lives for all: The University of Liverpool has signed a Memorandum of Understanding (MoU) with Roche Diagnostics UK and Ireland to advance research and innovation for improved health and community prosperity. Complex needs model: Paper published around the work to develop a segmentation model to identify household with high levels of complex cross-sectoral needs, to plan for integrated care services November 2024 Four years on – what have we learned from Liverpool’s Covid-19 testing response? To mark four years since Liverpool led the world’s first voluntary mass testing for Covid-19, The Pandemic Institute has collaborated with Professor Iain Buchan to produce a short film exploring the city’s response & how we can use data-driven community testing in future pandemics. Epilepsy Award: Congratulations to Gashirai Mbizvo on winning the 2024 Platform Presentation Award at the International League Against Epilepsy British Branch conference.
🎉 On 08 Dec 2024 the Civic Health Innovation Labs (@livunichil.bsky.social) celebrated its first year anniversary!
🧪 View a reflection on the highlights & milestones from the first year, showing how interdisciplinary research is tackling health challenges
🔗: www.liverpool.ac.uk/civic-health...
Purple and blue Venn diagram of people who celebrate Columbus Day v Flat Earthers. Intersecting at: celebrating a guy who sailed AROUND earth, still denying its round.
Maybe we all should try understanding the things we celebrate. #Solstice #Columbus #flatearther #Americans #science #history #geometry
Order is Disorder hiding
[myself]
Un grand bravo @stadebriochin.bsky.social !!!
Procès Samuel Paty. Pro charia, Priscilla Mangel assure n’être « pas radicalisée » charliehebdo.fr/2024...
Les écologistes : une capacité infinie à decevoir
www.20minutes.fr/politique/41...
Les mollahs sont dégonflés.
Oh que c'est bien dit, c'est un humour réaliste !
Apple Plan sur le web gagne enfin en pertinence avec sa propre version de Street View
www.frandroid.com/marques/2444...
