It would be nice to have an easy to use alternative to their software. We couldn't get it to work a few years ago because it needed more than 150GB of RAM for a WT dataset. It was storing most of the read information in memory at some point. We ended up cobbling something together with STAR solo.
⚠️New study: we mapped DNA-binding of topoisomerase TOP2B in cancer, uncovering surprising hotspots of DNA damage. TOP2B, normally essential for DNA stress relief, can act as a double-edged sword. co-led by @LiisUuskula @ChristianLee, out now @natcomms.nature.com www.nature.com/articles/s41... [1/7]
Repost the work-week crowd ;)
minimap2 adds support for short read spliced RNA-seq alignment! lh3.github.io/2025/04/18/s...
UHN's newest documentary—The Future of Transplant—shines a light on the historic accomplishments of @transplant-uhn.bsky.social, setting the stage for innovative breakthroughs transforming #transplant today! ✨🫁
Learn more about the legacy and people behind the discoveries ⬇️
RNA xkcd.com/3056
I made a starter pack for algorithmic genomics. It's certainly incomplete, but already has a ton of awesome peeps. Let me know if you know people I should add (with a focus on algorithms and data structures in genomics)
go.bsky.app/TRWCnZs
