Doug Dyer

1/ We are excited to report in @sciimmunology.bsky.social that human complete and selective LFA-1 deficiency causes isolated Epidermodysplasia Verruciformis (EV). This surprising phenotype revealed a surprising mechanism 🙂 www.science.org/doi/10.1126/...

Review @annualreviews.bsky.social @gabyrabi.bsky.social
Glycan-Binding Proteins in Immunity
www.annualreviews.org/content/jour...

Flyer of the Matrix Biology Europe conference listing invited speakers

Registration for #MBE2026 is now open!
Join us in Oulu 🇫🇮 for the flagship European meeting dedicated to fundamental #ECM research.
ECRs and trainees, this is a unique chance to connect with leaders in the field, present your work, gain visibility, and build your network!
More at www.mbe2026.org

You still have 3 days to apply to the postdoc positions available in my lab 😀
🔬Come and work with us 🔬

(President's Doctoral Scholar Award) A mechanistic understanding of microbe-immune cross talk in the face of pollutant challenge at The University of Manchester on FindAPhD.com PhD Project - (President's Doctoral Scholar Award) A mechanistic understanding of microbe-immune cross talk in the face of pollutant challenge at The University of Manchester, listed on FindAPhD.c...

📣 2026 PhD studentship 📣
Via @manchester.ac.uk 's President's Doctoral Scholar Awards, we are encouraging applications for a PhD on the effect of pollutant exposure on microbe-immune cross talk. This project will incorporate microbiology, immunology, & bioinformatics. Deadline: 16 March 2026!

One week left to submit your abstract for this fantastic meeting 👇 It’s gonna be a great year for matrix meetings! 😎 Fancy a full week of matrix biology? Catch a direct flight from Manchester to Frankfurt after #BSMB and join us in Heidelberg for #DGMB2026 😉

Reposting as one week left for early bird registration and to get your abstract in!!

Vaccine-induced immune thrombocytopenia and thrombosis occurs in persons with Ig light-chain allele IGLV3-21*02 or *03 that recognizes a specific epitope on the adenoviral core protein pVII, resulting in misdirection of antibody targeting PF4 @nejm.org
www.nejm.org/doi/full/10....

The sneeze secret: how much should you worry about this explosive reflex? It is one of the most powerful involuntary actions the human body can perform. But is a big sneeze a sign of illness, pollution or something else entirely?

Prof Sheena Cruickshank @sheencr.bsky.social offers insight in The Guardian @theguardian.com on the science behind sneezing and what it reveals about our health #ImmunoSky

www.theguardian.com/society/2026...

You still have time to apply if you are interested in joining my lab!!

Been on multiple search committees

For me (personally so YMMV)…I basically dismiss everything that’s labeled *submitted* unless there’s a preprint I can read

Huge thanks to sponsors Thistle Scientific Milltenyi @biologists.bsky.social Ludger

Very excited to announce that registration is open for the BSMB Spring 2026 meeting in Manchester, April 13-14th. Already an amazing lineup and lots of opportunities to speak!
Register, bsmb.ac.uk/meetings/ecm... @mcrcellmatrix.bsky.social

Introducing the amazing Dr Lily Koumbas Foley 🥰📚👩‍🎓 @crgglasgow.bsky.social @uofgsii.bsky.social

British Society for Immunology MIG seminar, Dr Alex Clarke, University of Oxford: “Powering the germinal centre reaction" Thursday 5th February 12 pm Michael Smith Lecture Theatre Lydia Becker Institute of Immunology and Inflammation

Dr Alexander Clarke @ajclarke.bsky.social joins us from
@ox.ac.uk tomorrow to give a talk entitled:

“Powering the germinal centre reaction"

📆 Thursday 5th Feb
🕛 12:00 PM
📍 Michael Smith Lecture Theatre

@britsocimm.bsky.social MIG Seminar #ImmunoSky

Join us in Sheffield! We are keen to support early career researchers in applying for independent research fellowships to join our friendly & collaborative environment, in areas related to gene expression, mechanistic cell biology & cancer biology.

For more info 👇
sheffield.ac.uk/biosciences/...

Science update from my postdoc Peiyuan Chai - his work “glycoRNA complexed with heparan sulfate regulates VEGF-A signaling” is now published @nature.com uncovering a new layer or glycoRNA-regulation of growth factor mediated control physiological processes rdcu.be/e1bBX

Fibroblastic reticular cells direct the initiation of T cell responses via CD44 @nature.com @the-de-lab.bsky.social
www.nature.com/articles/s41...

CELL MIGRATION LAB We study cell migration in health and disease

🚨 We are hiring TWO postdocs to join the Cell Migration Lab (cellmig.org) 🇫🇮 as part of the new Centre of Excellence in Immune–Endothelial Interfaces (IMMENs).
Join us to decode immune regulation & develop next-gen imaging tools! 🧪🔬
Details in thread 🧵👇
#ScienceSky #Postdoc #AcademicJobs Please RT🫶

Out now in @natchembio.nature.com: Xylosyltransferase engineering to manipulate proteoglycans in mammalian cells 🎉 www.nature.com/articles/s41... check out the press release below! #glycotime

An AI generated image showing a dense forest of glycans on the surface of the cell.

Have you ever wondered how many N-Glycans or #glycoproteins there are on cells?

The numbers are massive: calculations suggest about 20 to 200 million N-glycans per human cell!

Read the full blog post: research.bidmc.org/ncfg/blog/24...

#glycobiology #glycotime #cells #biology

#Glycans probably have more "copies/cell" than #proteins and changes in #glycosylation could potentially be remarkable biomarkers for diseases as well as targets for therapeutics. This post explores the abundance of glycans on the cell surface and it is worth a read to recognize these #biomolecules.

Really looking forward to speaking (for the 3rd year!) at the British Society for Immunology (@britsocimm.bsky.social) Foundations of Immunology course on 18 March 🧬

A brilliant one-day online course covering core immunology for all backgrounds 🧪

Register 👉 www.immunology.org/training/Fou...

Laboratory Engineer (Senior), in Advanced Imaging, 1.5.2026-31.12.2028

🚨 Job Alert! 🚨

We have an opening at our Microscopy Core Facility in Turku 🇫🇮.
If you love imaging 🔬 and helping scientists succeed, we want you! 👇

abo.rekrytointi.com/paikat/index...

#Microscopy #ScienceJobs #CoreFacility #Imaging
@turkubioscience.bsky.social

🥳 𝐄𝐱𝐜𝐢𝐭𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐨𝐮𝐫 𝐥𝐚𝐭𝐞𝐬𝐭 𝐰𝐨𝐫𝐤 𝐬𝐡𝐨𝐰𝐢𝐧𝐠 𝐡𝐨𝐰 𝐩𝐨𝐥𝐲𝐬𝐢𝐚𝐥𝐲𝐥𝐚𝐭𝐢𝐨𝐧, 𝐚 𝐫𝐚𝐫𝐞 𝐩𝐫𝐨𝐭𝐞𝐢𝐧 𝐦𝐨𝐝𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧, 𝐫𝐞𝐠𝐮𝐥𝐚𝐭𝐞𝐬 𝐢𝐧𝐟𝐥𝐚𝐦𝐦𝐚𝐭𝐨𝐫𝐲 𝐦𝐨𝐧𝐨𝐜𝐲𝐭𝐞 𝐦𝐨𝐛𝐢𝐥𝐢𝐳𝐚𝐭𝐢𝐨𝐧 𝐟𝐫𝐨𝐦 𝐭𝐡𝐞 𝐛𝐨𝐧𝐞 𝐦𝐚𝐫𝐫𝐨𝐰.

✍️ Aurélien Boyancé, Nelly Gilles, @yoannrombouts.bsky.social & coll. @ipbstoulouse.bsky.social

📖 shorturl.at/IDwza

👇 A short thread...

Our lab is hiring a PhD student to investigate how glycans affect antitumor immune responses in metastases and how this can be modulated to improve immunotherapy! More info here 👇
#glycotime

werkenbij.amsterdamumc.org/en/vacatures...

Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers - The EMBO Journal The rapid, transient, and unpredictable nature of interactions between circulating cells and the endothelium challenges the investigation of these events under flow conditions. Here, we developed an i...

Delighted to share the latest paper from the lab
"Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers"

Amazing work driven by @follainga.bsky.social with contributions from many.

link.springer.com/article/10.1...

Don't miss out on your chance to attend "Fuelling the immune response IV: #UKimmunometabolismMeeting2026"

Those that have joined before will know these are fantastic meetings providing an open & productive forum to discuss really cool science

📆16-17th April

www.immunology.org/events/fuell...

Major update for unilectin.unige.ch with now more than 2800 3D-structures with annotation, literature and details of interaction!! HumanLectome also up to date. Thanks to Boris Schnider at @sib.swiss and @glycoexpasy.bsky.social for super work. More exciting news soon with LectomeXplore upgrade

Antibody-lectin chimeras for glyco-immune checkpoint blockade - Nature Biotechnology Cancer immunotherapy benefits from antibody-lectin chimeras that block glyco-immune checkpoints.

Out now: We present antibody-lectin chimeras (AbLecs) as a molecular platform to target sugars, or glycans, for cancer immunotherapy.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
@mitkochinstitute.bsky.social @mitdeptofbe.bsky.social @mitcheme.bsky.social @stanford-chemh.bsky.social