Today in @nature.com, the @christophthaiss.bsky.social & @maayanlevy.bsky.social labs trace age-related memory loss to the gastrointestinal tract & map the complete gut-to-brain pathway driving it. Targeting this pathway can reverse cognitive aging in mice.
www.nature.com/articles/s41...
Many congratulations, looks so cool!
Great location π
Poster deadline is approaching for @keystoneSymposia.bsky.social #BCells & #PlasmaCells : Fundamental & Translational Biology, this March in Keystone! keysym.us/KSBCells26 #KSBCells26
Target stiffness influences T cell polarization and gene expression through distinct Ca2+ channels
www.science.org/doi/10.1126/...
One-step generation of TCR knock-in mice targeted to the TCRΞ² locus results in functional mature T lymphocytes https://www.biorxiv.org/content/10.64898/2026.01.13.699338v1
Congrats!
Urs MΓΆrbe, William Agace et al. characterize and spatially map the fibroblast landscape within human large and small intestinal gut-associated lymphoid tissues, including Peyerβs patches and isolated lymphoid follicles, during homeostasis and #Crohns disease. rupress.org/jem/article/...
#IBD
IgA plasma cell dynamics during homeostasis and immunization @cp-immunity.bsky.social
Preview @carlanowosad.bsky.social
www.cell.com/immunity/ful...
on
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
My latest 'pinch yourself' moment from the Lab. We previewed two really really exciting papers from the Eisenbarth and Pabst Labs for @cp-immunity.bsky.social
Read our summary here> www.cell.com/immunity/ful...
A big well done to Gaby Berman in my group and authors of both excellent manuscripts!
Absolutely thrilled to put this into the world-first Nowosad Lab preprint is live π₯² Check out what me and @thelundlab.bsky.social get up to when left to our own devices. Full breakdown to come, but for now let us know what you think. @nyulangone.bsky.social www.biorxiv.org/content/10.1... #immunosky
Taxpayers should not accept cuts in funding for cancer research. Bravo ππΎππΎππΎππΎππΎ @miriammerad.bsky.social
ππΌππΌππΌSign up to show New York State law makers that you want your tax dollars to fund life saving research www.nycures.org
Leaving Basel after an amazing @embo.org meeting on Barrier Immunity! Bravo @maurogaya.bsky.social and @immunologyking.bsky.social for putting together such a brilliant lineup.
Great analogy to illustrate the question @carlanowosad.bsky.social is pursuing on her lab: how GC are form and how GC cells find their way to their specific locations
#embo workshop Basel
#immunalogy
Fantastic @embo.org young investigator lecture on lung B cell responses from @maurogaya.bsky.social #EMBObarrierTissues
Superstar π€©
Vote for the extremely talented Helena here!!
Why does selection feel so weak relative to mutation in affinity maturation? A new blog post giving three perspectives, including our new transformer-based model of natural selection on antibodies: matsen.group/general/202...
Love this series! Great to see some familiar faces in here π
π§ͺ Senate appropriators say: NIH's budget gets a... boost!
Rather than 40% cut, NIH gets a $400M *increase* in the Senate committee bill for FY26 (about +1%).
"Congress has your back," said @murray.senate.gov.
ADVOCACY MATTERS! There's still a long road (esp in the House), so keep up pressure.
BREAKING: Trump wants to illegally cut off $15 billion in lifesaving NIH research.
Research to cure cancer, Alzheimer's, and so much more is on the line.
These people are LYING about waste, fraud, and abuse at NIH to justify attacking medical researchβwe all need to say so.
My full statement. β¬οΈ
And share widely please, both here and when you are chatting to great graduating students!
Starting up OnlyLabs, where people can pay to watch researchers who used to have federal funding do Hot Uncensored Cutting Edge science experiments.
Nowosad Lab will be recruiting postdocs soon. Reach out if you are interested!
S1P is produced in the outer lymph follicle area and degraded by B cells resulting in a negative gradient towards to follicle center. S1PR2 signalling on GC B cells leads to migration arrest, keeping B cells within the follicle. (π data)
Green et al 2011 π§ͺβ
www.nature.com/articles/ni....
'Under the new administration, the NIH, which for more than 75 years has supported scientists who are pursuing research deemed to be in our national interest, is pulling back. Budgets are being slashed.'
Big day for the lab today π§ͺ
Congrats to Gaby Berman, officially a Nowosad Lab PhD candidate!!
Please share this widely and encourage students to apply! Many of our current graduate students were recruited through this program -- happy to answer any questions and connect with students
bsky.app/profile/stan...
Cream puffs in a tip box can only mean one thing⦠a celebration!
Nowosad Lab milestone- first student qualifying exam complete π₯²
