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Yale Kavli Institute for Neuroscience

@kavliatyale

We aim to understand how genes, molecules, cells, and neural circuits interact to give rise to brain development and behavior, and to apply this knowledge to advance treatments for brain disorders. https://medicine.yale.edu/kavli/

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12.11.2024
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Latest posts by Yale Kavli Institute for Neuroscience @kavliatyale

Flyer of the Kavli Workshop on New Approaches to Gene-Based Therapeutics for Neurological and Neurodevelopmental Disorders on Friday, March 13th, 2026, from 1 to 5:15 pm (180, 100 College St)

Flyer of the Kavli Workshop on New Approaches to Gene-Based Therapeutics for Neurological and Neurodevelopmental Disorders on Friday, March 13th, 2026, from 1 to 5:15 pm (180, 100 College St)

Join us on 3/13 for a workshop on New Approaches to Gene-Based Therapeutics for Neurological and Neurodevelopmental Disorders 🧠🧬

Check the QR code to register & to submit questions for the panelists πŸ’¬πŸ‘₯ by March 10.

Yale only. Organized by @limlabyale.bsky.social & @ehoffmanlab.bsky.social

06.03.2026 17:29 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Adjusting to a shifting reality Our brains toggle between existing mental maps and new information.

In a new @natcomms.nature.com study, Yale Psychiatry & @yaleneuro.bsky.social's @georgedragoi.bsky.social found that when assessing a new environment, the brain switches 🧠 between prior mental maps πŸ—ΊοΈ. Dragoi suggests that this "mental flickering" may be essential to learning!

25.02.2026 19:23 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Methanol, mitochondria, and new science at CERN Yale researchers find a new way to convert methane into methanol, discern patterns in the placement of mitochondria in the brain, and offer new guidelines for managing functional seizures. Meanwhile, a Yale astrophysicist is part of the Impact 100 list of influential Indian Americans.

In a new @science.org study, @yale.edu researchers led by @yaleneuro.bsky.social's Damon Clark πŸ₯Ό mapped the organization of mitochondria 🦠 in neuronsβ€”revealing that the shape & structure of the organelles actually follow the logic of neural circuits! 🧠

Read More πŸ‘‡

24.02.2026 15:39 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Poster of 2 Upcoming Kavli Funding Opportunities (Kavli Innovative Teams Award 2026 and Kavli Postdoctoral Fellowship 2026)

Poster of 2 Upcoming Kavli Funding Opportunities (Kavli Innovative Teams Award 2026 and Kavli Postdoctoral Fellowship 2026)

🚨Don't forget to apply to this year's @kavliatyale.bsky.social Fellowships and Awards🚨

Applications are due on March 1 πŸ—“οΈ so apply today!

For more information on eligibility, application, and funding details πŸ‘‡

20.02.2026 20:29 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Our new paper showcasing molecular connectomics with pan-expansion microscopy is out in @natbiotech.nature.com! www.nature.com/articles/s41...
This wonderful collaboration with @bewersdorflab.bsky.social was led by Ons M'Saad (now founder/CEO of Panluminate) and @allisonphysics.bsky.social. (1/5)

27.11.2025 04:39 πŸ‘ 61 πŸ” 24 πŸ’¬ 1 πŸ“Œ 0
Adams Neurosciences Center Scheduled to open in 2027, the Neurosciences Center reflects Yale New Haven’s commitment to state-of-the-art, destination neurosciences care and biomedical imaging.

πŸ“’In 2027, Yale New Haven Hospital will open the ✨Adams Neurosciences Centerβœ¨β€”a cutting-edge hub for innovative neurological & neurosurgical care 🧠 serving patients nationwide! 🌎

Read more about this new center hereπŸ‘‡
www.ynhh.org/services/neu...

29.01.2026 12:49 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Researchers Discover Molecular Difference in Autistic Brains Brains of autistic individuals have fewer of a specific kind of glutamate receptor, supporting an idea that autism is driven by a signaling imbalance.

In a new study, @yaleschoolofmed.bsky.social researchers found that people with autism have fewer glutamate receptors 🧬, potentially causing an imbalance of excitatory & inhibitory signaling in the brain. πŸ”¬βœ¨

More πŸ‘‡
medicine.yale.edu/news-article...

15.01.2026 18:10 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Scientists map how the brain develops – and how it resolves inflammation Researchers at Karolinska Institutet and Yale University have created a multidimensional, molecular map of how the mouse brain develops after birth and how it reacts to inflammation.

In a new @nature.com com study, @gocastelobranco.bsky.social and @yale.edu's Di Zhang used spatial tri-omics to uncover shared molecular programs active during both brain development 🧠 and neuroinflammation!

Read More HereπŸ‘‡
engineering.yale.edu/news-and-eve...

03.12.2025 12:41 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Poster of 3 Upcoming Kavli Funding Opportunities (Kavli Innovative Teams Award 2026, Kavli Postdoctoral Award for Collaborative Excellence, and Kavli Postdoctoral Fellowship 2026)

Poster of 3 Upcoming Kavli Funding Opportunities (Kavli Innovative Teams Award 2026, Kavli Postdoctoral Award for Collaborative Excellence, and Kavli Postdoctoral Fellowship 2026)

🚨Applications for 2026's @kavliatyale.bsky.social Fellowships and Awards are officially open! 🚨

For more information on eligibility, application, and funding details πŸ‘‡
medicine.yale.edu/kavli/initia...

01.12.2025 13:23 πŸ‘ 6 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
New insight into how cilia on cell surfaces break down In a new study, Yale researchers identified a pathway that allows cells to β€œdisassemble” their cilia before division β€” and found a possible connection to a neurological disorder.

In a new study, @yale.edu's Shane Elliott, Paul Ready, and the
@davidbreslowlab.bsky.social identified 2 genes🧬that control how cells assemble & dismantle ciliaβ€”pointing to new strategies for treating diseases linked to ciliary breakdown!

Read More HereπŸ‘‡
news.yale.edu/2025/10/29/n...

17.11.2025 17:48 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
A growing number of U.S. adults report cognitive disability In a 10-year study, U.S. adults reported growing rates of problems with their memory, concentration, and decision-making abilities, with the figure doubling among the youngest cohort.

In a new study led by @yaleschoolofmed.bsky.social Adam de Havenon, researchers found a surprising riseπŸ“ˆin the percentage of young adults πŸ§‘β€πŸ€β€πŸ§‘ reporting cognitive impairmentsπŸ§ β¬‡οΈ

Read more about their findings & the potential public health implications here πŸ‘‡
news.yale.edu/2025/09/24/g...

05.11.2025 13:48 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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What Is Treatment-Resistant Depression? Treatment-resistant does not mean untreatable. Discover the evidence-based options for coping with this form of depression.

In a new article, @yaleschoolofmed.bsky.social's Dr. John Krystal discusses treatment-resistant depression: what it is, how it is diagnosed, and how new therapies are offering hope beyond traditional treatments! 🧠

Read More πŸ‘‡
www.everydayhealth.com/depression/t...

29.10.2025 13:01 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Flyer of Alzheimer Disease Research Center Seminar Series by Heather Snell, PhD on October 28th at 4pm

Flyer of Alzheimer Disease Research Center Seminar Series by Heather Snell, PhD on October 28th at 4pm

Join us tomorrow (10/28) for an ✨#Alzheimer's Disease Research Center Seminar✨ by @heatherdsnell.bsky.social, PhD

This event is open to the @yale.edu community only. πŸ“© The Zoom link is available via email.

We hope to see you there! See flyer for more πŸ‘‡

27.10.2025 15:08 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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The Brain Navigates New Spaces by β€˜Flickering’ Between Reality and Old Mental Maps A new Yale study reveals the brain's internal map doesn't just track one’s current location, it constantly "flickers" between the present space and remembered

In a new @natcomms.nature.com study led by
@georgedragoi.bsky.social and Yuchen Zhou πŸ₯Ό, researchers reveal how the hippocampus builds and updates internal maps πŸ—ΊοΈ of our surroundingsβ€”helping us navigate new & unexpected spaces!

Read More πŸ‘‡
medicine.yale.edu/news-article...

24.10.2025 14:50 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 1
Flyer for SYNAPSES Symposium (Thursday October 23rd at Room 116 at 100 College Street) with talks by Ann Rose Bright, PhD at 9:00am, Peter Hasenhuetl, PhD at 10:00am, Minhyeok Chang, PhD at 11:15am, and Zhenggang Zhu, PhD at 12:15pm. Registration QR code at top right.

Flyer for SYNAPSES Symposium (Thursday October 23rd at Room 116 at 100 College Street) with talks by Ann Rose Bright, PhD at 9:00am, Peter Hasenhuetl, PhD at 10:00am, Minhyeok Chang, PhD at 11:15am, and Zhenggang Zhu, PhD at 12:15pm. Registration QR code at top right.

Join us next Thursday (10/23) for #SYNAPSES, a senior postdoc symposium @yaleneuro.bsky.social @kavliatyale.bsky.social

Talks will be given by:
- @annrosebright.bsky.social, PhDπŸ‘©β€πŸ”¬
- Peter Hasenhuetl, PhD πŸ”¬
- Minhyeok Chang, PhD πŸ§‘β€πŸ”¬
- @zhenggang.bsky.social, PhD πŸ₯Ό

Register Today! Yale only.

16.10.2025 17:16 πŸ‘ 5 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
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Excited to share our new paper entitled Multisystem Environmental Factors Elucidate Shared and Distinct Associations With Brain and Behavior in Adolescents.

Link: www.jaacap.org/article/S089....

@kavliatyale.bsky.social

16.10.2025 21:41 πŸ‘ 12 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0
Flyer for Kavli Networking Hour on Friday, October 17th at 4pm. Registration QR code at bottom left.

Flyer for Kavli Networking Hour on Friday, October 17th at 4pm. Registration QR code at bottom left.

Happy Monday! πŸπŸ‚
Kick off your week to a great start by registering for THIS FRIDAY's (10/17) ✨ @kavliatyale.bsky.social Networking Hour✨ Food & drinks will be provided.

Thank you to the @mhigley.bsky.social lab for hosting! Open to all Yale neuroscientists - registration required & limited.

13.10.2025 18:48 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Sreeganga Chandra, PhD, presenting what to do and not to do during a chalk talk, in front of a full room of postdocs.

Sreeganga Chandra, PhD, presenting what to do and not to do during a chalk talk, in front of a full room of postdocs.

Thank you to everyone who joined this year’s @kavliatyale.bsky.social Chalk Talk - there were many of you!

And a big thank you to our incredible speakers @schandralab.bsky.social and @trevorsorrells.bsky.social, and all the faculty who gave feedback to postdocs during their mock chalk talks.

10.10.2025 19:22 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

I thought we would never work on gamma oscillations again, but I was wrong πŸ€·β€β™€οΈ So happy to see this work out in @nature.com! This was a truly epic project spearheaded by @q-perrenoud.bsky.social. Gamma isn't always an oscillation, but it's critical for sensory encoding and perceptual performance 🧠

08.10.2025 17:59 πŸ‘ 17 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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This 1 Hobby Is Great For An Aging Brain, According To A New Study If you want to protect your brain as you age, pick up this hobby.

Music might be keeping your mind sharp! 🎢🧠

In a new @buzzfeed.com article, @yaleschoolofmed.bsky.social's Fesharaki-Zadeh, MD, PhD, explains how making music can help build your brain’s cognitive reserve, keeping it resilient πŸ›‘οΈ against aging & disease.

06.10.2025 17:41 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Postdoctoral Fellowships | Wu Tsai Institute

WTI Postdoctoral Fellowship applications are open! Unique opportunity for those pivoting fields or working across disciplines. I’d be happy to support candidates with a background in immunology and/or in vivo 2-photon imaging, including collaborations with other WTI labs wti.yale.edu/initiatives/...

03.10.2025 18:32 πŸ‘ 7 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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Brain Activity is Increasingly Variable During Development Fluctuations in brain activity increase until mid-adolescence. Deviations from this trajectory are linked to worse executive functioning.

In a recent @cp-neuron.bsky.social study, @dscheinost.bsky.social and @yaleschoolofmed.bsky.social's Jean Ye found that neural variability πŸ§ β€”brain fluctuations that support flexible behaviorβ€”increases πŸ“ˆ through childhood πŸ‘Άbefore stabilizing in adolescence🧍

03.10.2025 13:38 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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How Gene Mutations Drive Dementia in Parkinson’s Disease New findings reveal motor and cognitive deficits arise through separate mechanisms in Parkinson’s disease, challenging previous thinking.

In a new @natcomms.nature.com study, Yale's @schandralab.bsky.social found that mutations in the GBA gene 🧬 may drive the cognitive decline 🧠 seen in individuals with #Parkinsons, as opposed to a buildup of alpha-synuclein as previously thought.

Read More πŸ‘‡

01.10.2025 18:32 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Parents are quietly trying ketamine therapy for their teens. It's highly controversial. Doctors say ketamine therapy can provide life-saving support in cases where other medications have failed, but there are potential risks involved.

In a new @usatoday.com article, @yaleschoolofmed.bsky.social's John Krystal, MD, both advocates for and cautions the use of ketamine therapy in teenagers suffering from depression.

30.09.2025 14:38 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Yale Scientists Seek to Uncover Neural and Genomic Mechanisms that Drive Anxiety An interdisciplinary team of researchers from the Departments of Psychiatry and Neurosurgery at Yale School of Medicine has launched a pioneering study aimed at

Supported by a $5M @wellcometrust.bsky.social grant, @yaleschoolofmed.bsky.social Depts of Neurosurgery & Psychiatry have launched a study to uncover the neural & genomic mechanisms driving anxiety. Initial pilot work was funded by Yale Center for Brain & Mind Health + @kavliatyale.bsky.social

26.09.2025 15:14 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Novel PET Tracer Detects Synaptic Changes in Spinal Cord and Brain After Spinal Cord Injury A new PET tracer can provide insights into how spinal cord injuries affect not only the spinal cord, but also the brain, according to new research published in The Journal of Nuclear Medicine

A new @journalofnucmed.bsky.social study shows how a novel PET radiotracer (SV2A) can track synaptic changes in a rat's spinal cord & brain post-injury.

@yaleschoolofmed.bsky.social's Jason Cai, PhD: "Our work has potential to revolutionize the way spinal cord injury is diagnosed."

24.09.2025 19:59 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Flyer for The Chalk Talk event on Oct 9.

Flyer for The Chalk Talk event on Oct 9.

🚨 Only 3 days left to register! 🚨
Yale postdocs, don’t miss the Oct 9th @kavliatyale.bsky.social Chalk Talk event, featuring tips by @schandralab.bsky.social & a mock talk by @trevorsorrells.bsky.social!

Register Today!πŸ‘‡
yalesurvey.ca1.qualtrics.com/jfe/form/SV_...

22.09.2025 18:41 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Quitting time: Neurons that drive sociable behavior in children and teens turn off in adulthood Researchers have mapped the neural signaling that drives social impulses critical to survival in youngΒ mammals.

Wonder why social needs differ from childhood to adulthood? πŸ€±βž‘οΈπŸ§‘ In a new @currentbiology.bsky.social study, @yaleschoolofmed.bsky.social researchers, led by Marcelo Dietrich, found that Agrp neurons in the hypothalamus 🧠 drive social needs during youth but slowly lose this role in adulthood.

15.09.2025 19:19 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Associations between fetal movement and maternal-fetal attachment in late pregnancy Maternal-fetal attachment (MFA) represents the evolving psychological bond between a pregnant person and their fetus, reflecting early emotional inves…

In a new study led by @kavliatyale.bsky.social graduate student @kathy-ayala.bsky.social πŸ‘©β€πŸ”¬, researchers studied 51 pregnant women in their third trimester🀰 and found that higher fetal movement was linked to stronger maternal-fetal attachment.🀱✨

Read more here πŸ‘‡

10.09.2025 17:09 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Online Survey | Built with Qualtrics Experience Managementβ„’ Qualtrics makes sophisticated research simple and empowers users to capture customer, product, brand & employee experience insights in one place.

πŸ“… Mark your calendars and join us Thursday, Oct 9, for the 2025 edition of the Kavli Chalk Talk! 🧠

Learn from @schandralab.bsky.social & @trevorsorrells.bsky.social about what makes a great chalk talk πŸ‘©β€πŸ«πŸ—£οΈ and senior postdocs can practice their own.

Register by Sept 25! (Yale only) πŸ‘‡

09.09.2025 14:36 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0