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American Journal of Kidney Diseases

@ajkd

AJKD, official journal of @kidney.org, is the leading source of information devoted to clinical nephrology research and practice. AJKD.org | AJKDblog.org | Organizer of #NephMadness @nephmadness.bsky.social

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Latest posts by American Journal of Kidney Diseases @ajkd

Perspectives on Deprescribing Medications Among Patients Receiving Hemodialysis: A Qualitative Study

bit.ly/3MLdj8z

07.03.2026 23:00 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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AJKD invites applications for its Editorial Internship Program, which will provide editorial experience to early career researchers interested in education, teaching, or medical editing/writing.

Apply by April 30. Details: bit.ly/3Z64pFG

07.03.2026 20:00 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Corticosteroid, Parathyroid Hormone, and Body Composition Associations With Bone Density and Structure Following Kidney Transplantation

bit.ly/47wHN6h #OpenAccess

06.03.2026 23:00 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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In celebration of #WorldKidneyDay on March 12, this special collection highlights kidney disease research from around the world:

bit.ly/3EUhrPN (FREE)

06.03.2026 20:00 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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The #AJKDBlog homepage has been transformed to #NephMadness HQ!

Topics include:
-IgA Nephropathy,
-AI
-Animal House
-Transplantation
-C3G
-Cerebronephrology
-POCUS
-Genetics

Happy reading: ajkdblog.org

06.03.2026 19:59 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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If you're organizing a #NephMadness group bracket, we've prepared the materials to share with the group ahead of time: bit.ly/NephMadness2...

Don't forget to tag us when you share your party pics!

06.03.2026 19:59 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
What is this madness 2026? It's NephMadness!
What is this madness 2026? It's NephMadness! YouTube video by Cathy Quinlan

What is this madness? #NEPHMADNESS explained by
@cathyquinlan.bsky.social:

youtu.be/irrdgLek4Og

06.03.2026 19:59 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Here is the #NephMadness 2026 bracket!

Submit your picks by March 31, 2026 here: bit.ly/2DvWyou

06.03.2026 19:59 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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#NephMadness 2026: Cerebronephrology Region Submit your picks! |Β @NephMadness | @nephmadness.bsky.social |Β NephMadness 2026 Selection Committee Member: David DrewΒ  Dr. David Drew is a Nephrologist and an Associate Professor of Medicine at Tu…

#NephMadness 2026: Cerebronephrology Region

Teams:
- Cerebronephrology in CKD
- Cerebronephrology in ESKD

Expert: David Drew
Writer: Colton Jensen
Execs: Dia Waguespack & @jrkott27.bsky.social

bit.ly/NM26Cerebro

06.03.2026 17:14 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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#NephMadness 2026: Animal House Region Submit your picks! |Β @NephMadness | @nephmadness.bsky.social |Β NephMadness 2026 Selection Committee Member: Autumn HarrisΒ  At NC State University, Dr. Autumn Harris investigates how kidneys regulat…

#NephMadness 2026: Animal House Region

Teams: Dogs vs Cats

Experts: Autumn Harris & Kelly Hyndman
Writers: Sarah Street & Susan DiGiovanni
Execs: @kidneywars.bsky.social & @nephrosparks.bsky.social

bit.ly/NM26Animals

06.03.2026 17:08 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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#NephMadness 2026: Genetics Region Submit your picks! |Β @NephMadness | @nephmadness.bsky.social |Β NephMadness 2026 Selection Committee Member: Eric Wallace Eric Wallace is a Professor of Medicine in the Division of Nephrology at the…

#NephMadness 2026: Genetics Region

Teams:
- PKD Masqueraders
- Fabry Treatment

Expert: Eric Wallace
Writers: Steven Clapp & Alyssa Steitz
Execs: @annaburgner.bsky.social & @ssfarouk.bsky.social

bit.ly/NM26Genetics

06.03.2026 15:03 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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#NephMadness 2026: C3G Region Submit your picks! |Β @NephMadness | @nephmadness.bsky.social |Β NephMadness 2026 Selection Committee Member: Bradley DixonΒ  Dr. Dixon is currently Professor of Pediatrics and Medicine and chief of t…

#NephMadness 2026: C3G Region

Teams:
- C3G Diagnosis
- C3G Treatment

Expert: Bradley Dixon
Writer: Aarushi Varshney
Execs: @nephrosparks.bsky.social & @kidneywars.bsky.social

bit.ly/NM26C3G

06.03.2026 14:38 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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#NephMadness 2026: POCUS Region Submit your picks! |Β @NephMadness | @nephmadness.bsky.social |Β NephMadness 2026 Selection Committee Member: Mohamed Hassan Kamel Mohamed Hassan Kamel is an Assistant Professor, nephrologist and int…

#NephMadness 2026: POCUS Region

Teams:
- POCUS in AKI
- POCUS in ESKD

Experts: Mohamed Hassan Kamel & Vandana Niyyar
Writer: Priyal Sakhuja
Execs: @jrkott27.bsky.social & @annaburgner.bsky.social

bit.ly/NM26POCUS

06.03.2026 14:36 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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#NephMadness 2026: Trolls of Transplantation Region Submit your picks! |Β @NephMadness | @nephmadness.bsky.social |Β NephMadness 2026 Selection Committee Member: Sam Kant @kantsmd Sam Kant is an Nephrologist & Transplant Physician at St. Vincent’s…

#NephMadness 2026: Trolls of Transplantation Region

Teams:
- BK
- CMV

Experts: Sam Kant & @germatologist.bsky.social
Writers: @beanbuddy.bsky.social & @drflashheart.bsky.social
Execs: @ssfarouk.bsky.social & @catochita.bsky.social

bit.ly/NM26Transplant

06.03.2026 14:34 πŸ‘ 2 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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The March 2026 issue is available now! The cover celebrates #WorldKidneyDay on March 12. Check out the plain-language summaries on what inspired each study, the basic approach taken, what was learned, and why it matters:

bit.ly/3P9HmYB

06.03.2026 14:02 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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In A Few Words: The Raisin Mantra by Kylie Manuppelli

bit.ly/3MY6hOn

05.03.2026 23:00 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Reversible HIF activation by pharmacological HIF-prolyl-hydroxylase inhibition. Schematic overview of hypoxia-inducible factor (HIF) regulation. The oxygen-sensitive HIF-Ξ± subunit is continuously synthesized and rapidly degraded under normoxic conditions. Proteasomal degradation of HIF-Ξ± is initiated by prolyl hydroxylase domain (PHD) dioxygenases and mediated by the von Hippel-Lindau (VHL)-E3-ubiquitin ligase complex. PHD dioxygenases, PHD1, PHD2 and PHD3 utilize molecular oxygen and 2-oxoglutarate (2OG) as substrates to hydroxylate the oxygen-sensitive HIF-Ξ± subunit at specific proline residues (Pro), with PHD2 being the main regulator of HIF activity in most cells.

Reversible HIF activation by pharmacological HIF-prolyl-hydroxylase inhibition. Schematic overview of hypoxia-inducible factor (HIF) regulation. The oxygen-sensitive HIF-Ξ± subunit is continuously synthesized and rapidly degraded under normoxic conditions. Proteasomal degradation of HIF-Ξ± is initiated by prolyl hydroxylase domain (PHD) dioxygenases and mediated by the von Hippel-Lindau (VHL)-E3-ubiquitin ligase complex. PHD dioxygenases, PHD1, PHD2 and PHD3 utilize molecular oxygen and 2-oxoglutarate (2OG) as substrates to hydroxylate the oxygen-sensitive HIF-Ξ± subunit at specific proline residues (Pro), with PHD2 being the main regulator of HIF activity in most cells.

Navigating Anemia Therapy in CKD: The Role of Hypoxia-Inducible Factor Activators

bit.ly/3NOciNx (OPEN ACCESS)

05.03.2026 17:00 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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AJKD invites applications for its Editorial Internship Program, which will provide editorial experience to early career researchers interested in education, teaching, or medical editing/writing.

Apply by April 30. Details: bit.ly/3Z64pFG

05.03.2026 14:00 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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#NephMadness 2026: IgA Nephropathy Region Submit your picks! |Β @NephMadness | @nephmadness.bsky.social |Β NephMadness 2026 Selection Committee Member: Laura Mariani @LauraMarianiMD Dr. Mariani is an Associate Professor and clinical research…

#NephMadness 2026: IgA Nephropathy Region

Teams:
- B-Cell Modulators
- Complement Inhibitors

Expert: Laura Mariani
Writer: Alessandra Tomasi
Execs: @nephrosparks.bsky.social & Dia Waguespack

bit.ly/NM26IgAN

05.03.2026 12:00 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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#NephMadness 2026: AI Region Submit your picks! |Β @NephMadness | @nephmadness.bsky.social |Β NephMadness 2026 Selection Committee Member: Lili ChanΒ @LilCh4n Dr. Lili Chan is Associate Professor of Medicine in the Department of …

#NephMadness 2026: AI Region

Teams:
- Computational Pathology
- Natural Language Processing

Experts: Lili Chan & Kuang-Yu Jen
Writers: Neil Evans & Aditya Yelamanchi
Execs: @catochita.bsky.social & @jrkott27.bsky.social

bit.ly/NM26AI

05.03.2026 11:57 πŸ‘ 2 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Welcome to #NephMadness 2026 Our beautiful baby has grown into a moody, hormonal teen.Β  That’s right, it’s year 14 of NephMadness!Β  Whether this is your first time or you are a seasoned veteran, we have all the inf…

Happy #NephMadness Month!

The 8 regions of #NephMadness 2026 have been revealed on the #AJKDBlog.

If you're a #NephMadnessNewbie, we explain everything here: bit.ly/NephMadness2...

Looking forward to the fun and learning with all of you!

05.03.2026 11:53 πŸ‘ 7 πŸ” 1 πŸ’¬ 9 πŸ“Œ 0
Preview
Kidney Commute NKF Mega Menu

Drs. El Shamy and Cohen unpack a recent AJKD publication that challenges how we think about dialysis, value, and the future of kidney care. This is not just history. It is strategy, ethics, and systems based practice in real time.

🎧 bit.ly/3DamjQ9

#Nephrology #AJKD

03.03.2026 23:00 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Unadjusted cumulative incidences of loss of employer-sponsored health insurance among patients on in-center hemodialysis and peritoneal dialysis. The incidence curves start at three months after dialysis initiation. Green, red, and blue lines respectively represent patients on peritoneal dialysis, in-center hemodialysis with a fistula, and in-center hemodialysis without a fistula. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; w/, with; w/o, without.

Unadjusted cumulative incidences of loss of employer-sponsored health insurance among patients on in-center hemodialysis and peritoneal dialysis. The incidence curves start at three months after dialysis initiation. Green, red, and blue lines respectively represent patients on peritoneal dialysis, in-center hemodialysis with a fistula, and in-center hemodialysis without a fistula. Abbreviations: HD, hemodialysis; PD, peritoneal dialysis; w/, with; w/o, without.

Changes in Employment Status After Initiation of Peritoneal and In-center Hemodialysis

bit.ly/4pKLXgA

04.03.2026 17:00 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Figure 1 Ten steps to achieve comprehensive medication management. Adapted from the Get the Medications Right Institute15 with permission of the copyright holder (Get the Medications Right Institute). Abbreviations: CMM, comprehensive medication management; OTC, over-the-counter.

Figure 1 Ten steps to achieve comprehensive medication management. Adapted from the Get the Medications Right Institute15 with permission of the copyright holder (Get the Medications Right Institute). Abbreviations: CMM, comprehensive medication management; OTC, over-the-counter.

Optimizing Comprehensive Medication Management in CKD: An Opportunity to Integrate Pharmacists in the Kidney Care Team

bit.ly/4u8FK1g

04.03.2026 11:00 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

There remains a significant and under-recognized gap in the care of dialysis patients. While CKD has seen tremendous developments, patients on dialysis continue to face highly complex medication regimens and impaired quality of life, much of which is exacerbated by medications themselves 1/ #NephSky

20.02.2026 11:49 πŸ‘ 0 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Figure 1 Seroprotection rate (proportion of individuals achieving titers β‰₯1:40) after standard influenza vaccination in solid organ transplant recipients. The size of the symbols indicates patient numbers in the study. Based on data in Chong et al

Figure 1 Seroprotection rate (proportion of individuals achieving titers β‰₯1:40) after standard influenza vaccination in solid organ transplant recipients. The size of the symbols indicates patient numbers in the study. Based on data in Chong et al

Vaccinations to Prevent Infections in Adult Individuals With CKD and After Kidney transplantation: A Review

bit.ly/4ub933E (OPEN ACCESS)

03.03.2026 17:02 πŸ‘ 2 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Preview
Welcome to #NephMadness 2026 Our beautiful baby has grown into a moody, hormonal teen.Β  That’s right, it’s year 14 of NephMadness!Β  Whether this is your first time or you are a seasoned veteran, we have all the inf…

Happy #NephMadness Month!

The 8 regions of #NephMadness 2026 have been revealed on the #AJKDBlog.

If you're a #NephMadnessNewbie, we explain everything here:
bit.ly/NephMadness2...

Looking forward to the fun and learning with all of you!

03.03.2026 14:42 πŸ‘ 1 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1
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Complement Inhibition in Immunoglobulin A Nephropathy: A Mini-Review

bit.ly/49n58Xx

03.03.2026 11:00 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Post image

The March 2026 issue is available now! Check out the plain-language summaries on what inspired each study, the basic approach taken, what was learned, and why it matters:

bit.ly/3P9HmYB

02.03.2026 23:02 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Figure 1 Study flow chart

Figure 1 Study flow chart

Hypophosphatemia During Kidney Replacement Therapy and Ventilator-Free Days: A Post-Hoc Analysis of the STARRT-AKI Trial

bit.ly/4r3Y1u4

02.03.2026 17:03 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0