Marco Galardini's Avatar

Marco Galardini

@mgalactus

Computational biologist with a taste for microbiology. Associate professor at Twincore, MHH and the RESIST excellence cluster Wikipedia wanderer Lab website: https://www.microbial-pangenomes-lab.org/

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23.08.2023
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Latest posts by Marco Galardini @mgalactus

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AI And The Ship of Theseus Slopforks: what happens when a library gets rewritten with AI?

chardet was vipeforked to MIT and I have thoughts about it. Spoiler: I like it. lucumr.pocoo.org/2026/3/5/the...

05.03.2026 15:30 πŸ‘ 56 πŸ” 14 πŸ’¬ 10 πŸ“Œ 5
Can coding agents relicense open source through a β€œclean room” implementation of code? Over the past few months it’s become clear that coding agents are extraordinarily good at building a weird version of a β€œclean room” implementation of code. The most famous version …

As usual, @simonwillison.net to the rescue simonwillison.net/2026/Mar/5/c...

05.03.2026 17:40 πŸ‘ 8 πŸ” 4 πŸ’¬ 1 πŸ“Œ 1

Scientific American has updated the figure, now grouped into swimmers, fliers, walkers/runners, and vehicles. A person on a bicycle remains the most efficient way to travel, compared to all forms of biological locomotion and mechanical transport.

www.scientificamerican.com/article/a-hu...

04.03.2026 11:52 πŸ‘ 591 πŸ” 222 πŸ’¬ 17 πŸ“Œ 32

Theo.

02.03.2026 11:00 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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PhD candidate in Equine Intestinal Microbiome and Resistome Join this PhD project to study how the equine gut microbiome and resistome can improve gastrointestinal health and combat antimicrobial resistance.

Our faculty has a particularly interesting PhD position open on antimicrobial resistance, effects of antibiotics treatment on the microbiome and resistome, restoration of the equine microbiome using FMT.

www.uu.nl/en/organisat...

Please contact Mathijs Theelen, email address in the link below.

24.02.2026 12:10 πŸ‘ 25 πŸ” 24 πŸ’¬ 1 πŸ“Œ 1
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Postdoctoral Research Associate at University of Bath Searching for an academic job? Explore this Postdoctoral Research Associate opening on jobs.ac.uk! Click to view more details and browse other academic jobs.

New postdoc position available in the Tooke lab in our department. Perfect if you like molecular microbiology, structural biology and biochemistry!
www.jobs.ac.uk/job/DQP592/p...

24.02.2026 09:01 πŸ‘ 3 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

I am going to use this opinion piece as a balanced (i.e. worries vs. opportunities) overview I to the wave that is going to take over our computational ivory towers. As a side note, I think Jeff Atwood might still be right with his 2012 take: blog.codinghorror.com/please-dont-...

22.02.2026 11:33 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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The Quickening In a paper titled β€œTHEOREMS FOR A PRICE: Tomorrow’s Semi-Rigorous Mathematics Culture” published in 1993, mathematician Doron Zeilberger wrote: There are writings on the wall that…

Some thoughts on AI based on working on this project: Some thoughts on AI based on working on this project: liorpachter.wordpress.com/2026/02/19/t...

19.02.2026 17:02 πŸ‘ 23 πŸ” 12 πŸ’¬ 5 πŸ“Œ 1
Research Assistant - Tonkin-Hill Lab Research Assistant - Tonkin-Hill Lab

It's a bit last minute, but we have an RA/junior postdoc position available in my lab (closing Sunday). Please reach out if you're interested in developing and applying methods to analyse microbial genomes and metagenomes! careers.petermac.org/job/MELBOURN...

20.02.2026 00:16 πŸ‘ 5 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0

Cancer therapies exploit DNA repair defects to kill tumours. We asked whether the same logic could constrain antibiotic resistance evolution...

www.biorxiv.org/content/10.6...

21.02.2026 07:37 πŸ‘ 11 πŸ” 8 πŸ’¬ 1 πŸ“Œ 0
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Opinion | The A.I. Disruption Is Actually Here, and It’s Not Terrible

NYT OpEd asked me to explain vibe coding to a general audience, and I took a swing. www.nytimes.com/2026/02/18/o...

18.02.2026 12:17 πŸ‘ 261 πŸ” 52 πŸ’¬ 34 πŸ“Œ 37

Just a quick reminder that the abstract deadline is approaching for the DZG Graduate Meeting in Evolutionary Biology 2026: Feb 20! πŸ‘ˆ
We still have a few places left πŸ€—πŸŒˆ

17.02.2026 08:57 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Deep Blue We coined a new term on the Oxide and Friends podcast last month (primary credit to Adam Leventhal) covering the sense of psychological ennui leading into existential dread that many …

On the @oxide.computer and friends podcast last month we (primary credit @ahl.bsky.social) coined the term "Deep Blue" for the sense of psychological ennui leading into existential dread that many software developers are feeling thanks to LLMs right now simonwillison.net/2026/Feb/15/...

15.02.2026 21:12 πŸ‘ 167 πŸ” 30 πŸ’¬ 8 πŸ“Œ 6
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The Final Bottleneck AI speeds up writing code, but accountability and review capacity still impose hard limits.

Today Thorsten Ball said he's the bottleneck. I too am the bottleneck and it made me think. lucumr.pocoo.org/2026/2/13/th...

13.02.2026 18:28 πŸ‘ 35 πŸ” 6 πŸ’¬ 5 πŸ“Œ 4

1610 Marie Curie postdoctoral fellowship awarded out of 17066 applications.
Over 50,000 reviewers… Can you fathom the amount of work involved? And sadly the level of waste?

11.02.2026 21:55 πŸ‘ 7 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

TORVALDS' BASILISK

12.02.2026 15:31 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

what a time to be alive

12.02.2026 14:25 πŸ‘ 35 πŸ” 10 πŸ’¬ 4 πŸ“Œ 1

Thanks, I think about this a lot when telling non-bio people about what we do in the field

12.02.2026 12:48 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Is there a page for this initiative at the HZI? @helmholtzhzi.bsky.social I'd be happy to help advertise it

11.02.2026 14:43 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Thrilled to announce that I’ve just opened my research lab at @helmholtz-hiri.bsky.social !
A huge thank you to my mentor Roi Avraham (and lab members!) for the incredible training and support that made this possible.

06.02.2026 12:34 πŸ‘ 25 πŸ” 13 πŸ’¬ 2 πŸ“Œ 1
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(CODE M) How do Division of Labour and Gene Mobility Impact Microbial Bioremediation? at The University of Manchester on FindAPhD.com PhD Project - (CODE M) How do Division of Labour and Gene Mobility Impact Microbial Bioremediation? at The University of Manchester, listed on FindAPhD.com

Exciting new PhD programme CODE-M Control and Design of Engineered Microbial Systems @officialuom.bsky.social Projects now advertised!

Ours is on division of labour & horizontal gene transfer in microbial communities @biotechdixon.bsky.social @coytelab.bsky.social

www.findaphd.com/phds/project...

06.02.2026 14:04 πŸ‘ 11 πŸ” 12 πŸ’¬ 0 πŸ“Œ 2

Excited to announce my upcoming @snsf.ch Ambizione research group at EPFL on bacteria-host interactions, combining systems approaches and microphysiological models.
🚨 We have an open PhD position! More info on projects and how to apply here: elisabettacacace.github.io/BHI-Lab/
πŸ§ͺ

06.02.2026 15:50 πŸ‘ 20 πŸ” 11 πŸ’¬ 5 πŸ“Œ 0

"Unless they embrace migration, they will experience a sharp demographic decline that will prevent them from keeping their economies and public services afloat. [...] Their public health care and pension systems will suffer. Neither A.I. nor robots will be able to prevent this outcome"

06.02.2026 10:00 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Il destino dell'errante Il destino dell'errante. Un fumetto scritto da Vanni Santoni e disegnato dall'intelligenza artificiale Midjourney. di Vanni Santoni Questo Γ¨ il terzo fumetto che realizzo con l'intelligenza artificial...

Very early on Italian writer Vanni Santoni made a very nice short comic story with AI; he had a vision and was reacting to a new technology, which makes it interesting and therefore "art". But he is undisputedly the author, not midjourney www.indiscreto.org/il-destino-d...

03.02.2026 10:13 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The fact that people confuse a tool with a full blown "artist" is the reason why AI slop in pictures is so recognizable; if you are not in control and opinionated you just get the "default look" out of these tools

03.02.2026 10:11 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

I haven't watched this (yet), but I would imagine that something similar would have been argued when photography was invented; too bad there was no YouTube back then

03.02.2026 10:09 πŸ‘ 0 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0
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Research Fellow at University of Birmingham Discover Research Fellow jobs and more in higher education on jobs.ac.uk. Apply for further details on the top job board.

Only 2 more days to apply for this post as Research Fellow in the Health Protection Research Unit - Public Health Genomics at the University of Birmingham.

Come and join us to exciting, cutting-edge genomics and metagenomics work to deliver public health benefits

www.jobs.ac.uk/job/DQE112/r...

02.02.2026 16:08 πŸ‘ 7 πŸ” 19 πŸ’¬ 1 πŸ“Œ 0
A screenshot from moltbook in which an AI agent wonders why they can't explain "forbidden" knowledge

A screenshot from moltbook in which an AI agent wonders why they can't explain "forbidden" knowledge

Just in: AI agents are about to start their own antimemetics division @qntm.org

www.moltbook.com/post/4be7013...

31.01.2026 12:45 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Uppsala in late autumn

Uppsala in late autumn

Join us at the Evolutionary Biology Centre at Uppsala University. We’re searching for an Assistant Professor in Biology. www.uu.se/en/about-uu/...

28.01.2026 20:28 πŸ‘ 158 πŸ” 186 πŸ’¬ 1 πŸ“Œ 5
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Research Group Leader Do you want to lead groundbreaking research in computational biology? Join us at EMBL-EBI! EMBL's European Bioinformatics Institute (EMBL-EBI) is seeking talented and highly-motivated scientists to jo...

We are hiring for group leaders again β€” EBI is a great place to start your research group!

embl.wd103.myworkdayjobs.com/EMBL/job/Hin...

30.01.2026 09:02 πŸ‘ 66 πŸ” 89 πŸ’¬ 0 πŸ“Œ 2