Orna Issler

Pittsburgh 'Stand Up for Science' rally to bring attention to impacts of immigration crackdowns The National “Stand Up for Science” day of action returns to Pittsburgh tomorrow for the second year in a row to protest government actions and policies affecting scientific institutions, research and...

Rallies tomorrow around the country!

@standupforscience.bsky.social

Find one near you.

www.standupforscience.net

www.wesa.fm/health-scien...

"Cross-Organ Neuroimmunology of Behavior". Xuanming Guo and I discuss a new framework that reconceptualizes behavior as an emergent property of a distributed, brain-body neuroimmune network. lnkd.in/eihqZ_ay. @sinaiimmuno.bsky.social @sinaibrain.bsky.social

New postdoctoral opportunity @lieberinstitute.bsky.social working w/ @tsawada1.bsky.social and our Molecular Neurogenetics team using human induced pluripotent stem cells to investigate molecular, cellular and neuroendocrine mechanisms by which impaired placental function impacts brain development

I am so proud to share @forrestdrogers.bsky.social’s postdoctoral magnum opus, now out in @nature.com! Forrest discovered a novel role for Agouti in the MPOA of the hypothalamus to integrate socio-environmental information to flexibly tune paternal behavior
www.nature.com/articles/s41...
Thread! 👇🏻

AMAZING!!! CONGRATULATIONS!!!

📣📣📣 This is a call for PhD students in neuroscience!

✅ Are you a senior PhD student in neuroscience? 🧠
✅ Looking for career development opportunities?💼
✅ Want to visit NYC in spring?🗽
✅ Considering a postdoc at NYU? 🥼
✅Apply for CoNNExINS!

wp.nyu.edu/connexins/

Please RT!

Very excited to get to share culmination of this large-scale project to understand spatial gene expression in schizophrenia. Really proud of the amazing team work here working out lots of roadblocks to deploy these spatial strategies and analysis methods at scale!

Congratulations Tallie!!! A beautiful study

Hippocampal estrogen levels, receptor types, and epigenetics contribute to sex-specific memory vulnerabilities to concurrent acute stresses Acute concurrent stresses provoke lasting, sex-dependent memory problems. Hokenson, Rodríguez-Acevedo, et al. find that high hippocampal estrogen levels in mice generate permissive chromatin states, a...

Check out our new paper, investigating the role of estrogen in stress-induced memory disruptions. 🧠 online now!

www.cell.com/neuron/fullt...

@talliezee.bsky.social @eahellerphd.bsky.social

Environmental enrichment and physical exercise prevent stress-induced social avoidance and blood-brain barrier alterations via Fgf2 - Nature Communications Chronic stress disrupts the brain vasculature and contributes to mood disorders, but mechanisms of resilience remain unclear. Here, the authors show that enriched environments increase astrocytic Fgf2...

Out in its final form! Congratulations @sejpaton.bsky.social @jolusolo.bsky.social Alice Cadoret @adelinec.bsky.social @luisa-binder.bsky.social Béatrice Daigle @laura-mb.bsky.social Laurence Dion-Albert @katarzynaadudek.bsky.social @manonlebel5.bsky.social 🥂🧠🤓

www.nature.com/articles/s41...

Neuroscience MSc Neuroscience MSc

Fully funded international MSc in neuroscience.
Come! international.tau.ac.il/Neuroscience...

Huge thank you to @scottrussophd.bsky.social and @talliezee.bsky.social for supporting my nomination

I am thrilled to join the ACNP community! Feels like home!

Undergraduate Summer Research Training in Neuroscience | NYU Langone Health NYU Langone’s Neuroscience Institute offers a 10-week summer research training program in neuroscience for undergraduate students.

Undergrads, come and spend the summer with us! Applications for our Summer Research Training in Neuroscience are open now! med.nyu.edu/departments-...

Proud of Megan Kirchgessner for being named a rising ⭐️ of neuroscience 2025 by the @thetransmitter.bsky.social #SfN25

Totally! You opened a field of research! You should be super proud of yourself!

Estrogen modulates reward prediction errors and reinforcement learning - Nature Neuroscience Dopamine encoding of reward prediction errors naturally fluctuates over females’ reproductive cycles with estrogenic signaling due to reduced expression of dopamine reuptake proteins.

Thrilled to share our new paper, out now in @natneuro.nature.com, uncovering how estradiol, the most potent estrogen, modulates reinforcement learning and reward prediction errors across biological levels. www.nature.com/articles/s41...

#blueprint 1/7

Congratulations Carla!

Mazal Tov! Very well deserved!

We’re so psyched for this - check out our amazing lineup of speakers!!! Spots are going fast - register today!!! 👇

More than 30% of this century’s science Nobel prizewinners immigrated: see their journeys The most common destination for eventual Nobel laureates in physics, chemistry and medicine since 2000 is the United States, Nature has found.

You've probably heard how a high percentage of #Nobel laureates are immigrants. The US in particular has benefited from the influx of bright minds.

@jennaahart.bsky.social ran the data for this century's Nobel prizewinners — and shows more than 30% immigrated. 🧪

www.nature.com/articles/d41...

Yesterday was a good day:

The honor of being called a Dorothy Lambiase Derchin Scholar in Gender-Specific Medicine

A ceasefire

Optimism and relief

Important negative data!

A new @nature.com feature on autism with real data and facts
Published today, written before the Tylenol debacle.
' Kennedy and the HHS are “going to falsely
declare the cause for autism — and that that
gets in the way of a great deal of progress”.'
www.nature.com/articles/d41...

Remember: If we allow ourselves to fall into fatalism, or wallow in disappointment, or become resigned to what is rather than what should be, we will lose the long game.

The greatest enemy of positive social change is cynicism about what can be changed.

Not spatially resolved?

Only single cell sequencing of the all these post docs will reveal why

Just happened to me too!

Potentiation of mitochondrial function by mitoDREADD-Gs reverses pharmacological and neurodegenerative cognitive impairment in mice - Nature Neuroscience Activation of Gs signaling at mitochondria by mitoDREADD-Gs increases mitochondrial metabolism, leading to better memory in mouse models of dementia, directly linking brain mitochondrial deficits to c...

Potentiation of mitochondrial function by mitoDREADD-Gs reverses pharmacological and neurodegenerative cognitive impairment in mice

www.nature.com/articles/s41...

Corticotropin-releasing hormone modulates NREM sleep consolidation through the thalamic reticular nucleus Nature Communications - Corticotropin-releasing hormone (CRH), known for activating the HPA axis during stress, also acts centrally in the brain. Here, the authors show that CRH modulates thalamic...

Happy to announce our new paper in Nature Communications: rdcu.be/eBpGY
We show how CRH in the thalamic reticular nucleus modulates NREM sleep, helping to understand how stress impacts sleep

Congrats to Loredana Cumpana and team, in work led by Simone Astori!
@epfl-brainmind.bsky.social‬