@janetka20
Medicinal chemist interested in cancer and infectious disease (Fimbrion and WashU). Kinase, protease, GPCR, PDE and lectin inhibitor drug discovery. Antibacterial, antiviral, anthelmintic, anti-parasitic. Small molecule, peptide and carbohydrate.
Why was this story on the front page of the UKβs Daily Telegraph β but NOT Americaβs leading newspapers?
Graph of award probability of R35 and R01 from NIH factbook as a function of review rank percentile. As is apparent, 2025 is a significant departure, with lower award probabilities at all scores <40 and significant departures from norm, where even being in the top 10% is no longer a nearly certain indicator of success. Data source: https://report.nih.gov/nihdatabook/report/302
The data is in: the NIH goalposts have shifted.
What were once almost certain fundable scores have become coin flips and what used to be likely grants have become aspirational, leading to fewer awards.
Another manifestation of how HHS policies have led to fewer awards and less science.
And this is all he had to replace Noem.
I am frankly more concerned about the apathy of the American public and even more importantly the lack of leadership in the Democratic Party.
This is not a dress rehearsal. Every single American must speak out against this Facist administration.
This is insane
An announcement that the Senate voted to reauthroize the SBIR/STTR program.
The Senate has (finally) voted to reauthorize the small business SBIR/STTR program.
Not reauthorized yet, but this was likely the biggest hurdle.
Seems to be the patternβ¦
We killed 85 schoolgirls. We are not the good guys.
This is why it's not enough for Congress to just appropriate funds to scientific agencies. How the funds are or are not spent and when they are spent needs to be enforced.
The administration is playing games with our taxpayer dollars, when they should be going towards scientific innovation.
"The woman who directly named Trump in her abuse allegation claimed that around 1983, when she was around 13 yrs old, Epstein introduced her to Trump who subsequently forced her head down to his exposed penis which she subsequently bit. In response, Trump punched her in the head and kicked her out."
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Itβs not leadership anymore itβs a circus, and everyoneβs fighting for center ring.
cdn.factcheck.org/UploadedFile...
The link above shows what the MAGA Trump supporters put in our White House and EXACTLY what the MAGA GOP House and Senate are protecting.
Trump raped a 13-year-old child multiple times, hit her when she said stop, and threatened the lives of her family. A SCUMBAG
Hopefully it increases exponentially in April and May after council meetings
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Trump is in the Epstein files over ONE MILLION TIMES which means they redacted his name at least 962,000 times.
Good morning. The President of the United States was in the middle of the most serious child sex trafficking ring of the last quarter century.
He is referenced not a dozen times in the case files. Not 100 times. Not 1,000 times. Heβs referenced 38,000 times.
Please share. π
I have been thinking all day about the number of times unarmed Black people were killed by police on the pretext that their cell phone looked like a gun. And people would say βoh but you just donβt know what the truth is.β Well here it is.
The man was confronted because he was filming them - he had his phone in hand - the gun was holstered
They tackled beat & murdered him in ICE cold blood & then they fucking LIE
Does it have anything about reinstating the sbir program?
This is very revealing about intent and response.
We have to continue to appreciate that a major goal is intimidation and they see steps up to murder as acceptable tactics.
π’ CARB-X Novel Chemistry for AMR Challenge!
CARB-X is seeking applications for novel chemistry plans against known #AMR targets. The aim is to unlock innovative starting points for therapeutics to address drug-resistant bacterial infections. #IDSky #ChemSky π§ͺ
π bit.ly/4blmsyN
@bostonu.bsky.social
@bulaw.bsky.social
@asprgov.bsky.social
@niaidnews.bsky.social
@wellcometrust.bsky.social
@gatesfoundation.bsky.social
@dzif.bsky.social
Right after RenΓ©e Goodβs disgusting murder, a ICE goon was filmed kicking her memorial candles.
Absolutely vile.
How can we study target engagement and selectivity of covalent inhibitors? Which electrophilic probes are best suited to study a certain amino acid?
Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7)
www.nature.com/articles/s41...
Submit your research to JCM's Special Series, "Diagnostic Testing for Mycobacteria."
Tuberculosis (TB) remains one of the worldβs leading infectious killers, and NTM infections are rising. #JClinMicro invites submissions to our "Diagnostic Testing for Mycobacteria" series. π Share your research now β asm.social/2B6
New NIH Notice about International Collaborations
grants.nih.gov/grants/guide...
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