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Advanced Cell Diagnostics (ACD)

@acd-bt

Leader in single-molecule, single-cell RNA expression analysis, products & services based on proprietary RNAscope Technology. +70,000 probes. A Bio-Techne brand

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24.04.2025
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Latest posts by Advanced Cell Diagnostics (ACD) @acd-bt

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Hear from Dr. Marta Paterlini (Karolinska Institutet) as she demonstrates #RNAscope enables validation of snRNA-seq findings, same-section RNA + protein co-detection, and spatial discrimination of neural progenitors.
Register: info.bio-techne.com/webinar-spat...

23.02.2026 23:20 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Reveal Functional Protein Interactions with ProximityScopeβ„’ Spatial Assay Built upon Advanced Cell Diagnostics RNAscopeβ„’ technology, this novel ProximityScopeβ„’ assay is designed to reveal functional protein-protein interactions within intact tissues, delivering a spatial solution to explore how molecular signaling shapes disease processes. Learn More: https://www.bio-techne.com/applications/spatial-biology/rnascope-multiomics/proximityscope-assay

Go beyond expression, see protein interactions where they actually happen!
ProximityScope Assay enables spatially resolved protein-protein interaction detection, preserving tissue morphology and integrating seamlessly with #RNAscope multiomic workflows. bit.ly/3ZjUkFa

19.02.2026 22:39 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Join us on Feb 19, 9am PT for a spotlight review showcasing breakthrough RNAscope publications from 2025. Debia Wakhloo will highlight key publications utilizing RNAscope, BaseScope, & miRNAscope to address important spatial multiomic questions.
Register: bit.ly/49LASpR

12.02.2026 15:18 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Adipose tissue of an adult mouse after 12 weeks of high-fat diet feeding and 7 days post-traumatic brain injury, combining IF and FISH (RNAscope)."

Congratulations to Gideon van der Linden in UCD, on being selected for our next ECRN Researcher Spotlight! πŸŽ‰πŸ‘πŸ…

17.12.2025 18:52 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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#ThrowbackThursday in JHC: "RNAscope Multiplex FISH Signal Assessment in FFPE and Fresh Frozen Tissues: The Effect of Archival Duration on RNA Expression."

Click to read for FREE: bit.ly/3DxNTHk

#RNA #RNAscope #pathology

22.01.2026 23:22 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Microscopy image showing different type of neurons labeled in green, red and purple in a section of mouse brain in the frontal cortex

Microscopy image showing different type of neurons labeled in green, red and purple in a section of mouse brain in the frontal cortex

For #FluorescenceFriday, activity-trapping experiments to better understand how amphetamine controls attention. RNAscope for glutamate neurons 🟒, inhibitory neurons πŸ”΄ and our "ensemble" 🟣. Quotes for the loaded definition ;)

Image credit to JHU neuro student Suhaas Adiraju πŸ§ πŸ”¬πŸ§ͺ

30.01.2026 15:00 πŸ‘ 34 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0
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Join your fellow researchers, clinicians, and industry innovators from around the world for our free, interactive online event!
Co-organized with Lunaphore, The Spatial Biology Week 2026 is open for registration: lunaphore.com/our-events/t...
March 9-13
11am-1pm EDT | 4-6pm CET

10.02.2026 00:51 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

We love this @martinowk.bsky.social - another beautiful #ArtofRNAscope image -thank you!

06.12.2025 00:59 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Giving thanks to all this holiday season. We appreciate you #AdvancingYourMultiomicRNAscope in so many spatial ways using RNAscope ISH technology. Learn more about our #SpatialMultiomics at www.bio-techne.com/multiomics #GetMultiomicin2026

26.11.2025 22:07 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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We're here at #SfN25 @sfn.org - come meet us at booth #3217 Day 1 was so much fun!

Unlock the complex brain microenvironment with true #spatialmultiomics and learn how RNAscope technology can equip you with tools to drive breakthroughs in neuroscience

info.bio-techne.com/advance-disc...

18.11.2025 00:52 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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We're looking forward to seeing you in San Diego for Neuroscience 2025 (@sfn.org). Join the Bio-Techne Spatial Biology Division at booth #3217 and learn how we can unlock the complex brain microenvironment with #spatialmultiomics #SfN25
Learn More: bit.ly/4i6WEIb

13.11.2025 21:06 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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We're here, at Society for Immunotherapy of Cancer (SITC) @sitcancer.bsky.social and ready to empower you to use true #spatialmultiomics to accelerate your immunotherapy research.
Join the Advanced Cell Diagnostics and Lunaphore team at booth #603 and discover our extended #spatial portfolio.

08.11.2025 00:57 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Meet the team while reviewing our posters (87, 73, 74, 72) at
@sitcancer

Empowering immuno-oncology with scalable assays and fully automated same-section #spatialmultiomics, powered by #RNAscope & delivering unmatched precision and flexibility. Learn More: bit.ly/3JnTtyY

08.11.2025 00:55 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Announcing the launch of ProximityScope Assay to advance spatial protein-protein interactions research. Enabling simultaneous visualization of functional protein-protein interactions directly within fixed tissue at subcellular resolution.
Press Release: bit.ly/3WuHHWq

28.10.2025 11:08 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Top: Example confocal micrograph showing astrocyte expression of S100Ξ² (green), Cre-RFP (magenta), and H1R mRNA (cyan). Left: summed z-projection of all three confocal channels. Middle: RNAscope detected H1R mRNA with white and yellow arrows indicating example WT (S100Ξ²+/RFPβˆ’/H1R+) and cKO (RFP+/H1Rβˆ’) soma regions of interest (ROIs), respectively. Right: Cre-RFP expression (top, magenta) and S100Ξ² expression (bottom, green). Scale bars = 10 ΞΌm. Bottom: Example confocal micrograph showing astrocytic Cre-RFP (magenta), neuronal NeuN (green), and nuclear marker DAPI (blue). Left: summed z-projection of all three confocal channels. Middle: astrocytic Cre-RFP signal with astrocyte soma ROIs overlaid. Right: NeuN signal with astrocyte soma ROIs overlaid. Scale bars = 50 ΞΌm.

Top: Example confocal micrograph showing astrocyte expression of S100Ξ² (green), Cre-RFP (magenta), and H1R mRNA (cyan). Left: summed z-projection of all three confocal channels. Middle: RNAscope detected H1R mRNA with white and yellow arrows indicating example WT (S100Ξ²+/RFPβˆ’/H1R+) and cKO (RFP+/H1Rβˆ’) soma regions of interest (ROIs), respectively. Right: Cre-RFP expression (top, magenta) and S100Ξ² expression (bottom, green). Scale bars = 10 ΞΌm. Bottom: Example confocal micrograph showing astrocytic Cre-RFP (magenta), neuronal NeuN (green), and nuclear marker DAPI (blue). Left: summed z-projection of all three confocal channels. Middle: astrocytic Cre-RFP signal with astrocyte soma ROIs overlaid. Right: NeuN signal with astrocyte soma ROIs overlaid. Scale bars = 50 ΞΌm.

What's the function of #histamine -1-receptors (H1Rs) on cortical astrocytes? @kiraposkanzer.bsky.social & co show that astrocytic H1R signaling modulates Ca2+ activity, extracellular adenosine & REM #sleep, revealing a key #astrocyte role in sleep-wake regulation @plosbiology.org πŸ§ͺ plos.io/4gRj9Ap

03.10.2025 16:26 πŸ‘ 9 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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On #WorldHeartDay we celebrate research by Zhe Yu et al, from UCSD Skaggs School of Pharmacy. Using #RNAscope Multiplex Fluorescent v2 and custom RNAscope probes, they identified CMs at each stage of mitosis, providing new insights for cardiac science research.
Read more: doi.org/10.1038/s420...

29.09.2025 23:09 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Bio-Techne Introduces Innovative Tools for Spatial Biology Advancements Discover how Bio-Techne is transforming translational research with new spatial biology solutions that bridge research and clinical applications effectively.

Bio-Techne Introduces Innovative Tools for Spatial Biology Advancements #USA #Bio-Techne #Long_Beach #RNAscope #Lunaphore

26.09.2025 10:34 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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On World Alzheimer’s Day, we recognize the cutting-edge research presented in this Nature Neuro publication. #RNAscope Multiplex Fluorescent assay was used to identify APP and BACE1 expressing oligodendrocytes (OLs)
Read more: doi.org/10.1038/s415...
#WorldAlzheimersDay #AdvancingYourRNAscopeISH

22.09.2025 16:05 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Join our Professional Assay Services team for a Symposium in Cambridge, MA on Oct 2
Discover how our spatial multiomic services can accelerate therapeutic development. Glean insights on advancing preclinical and clinical studies with RNAscope.
Register here: engage.bio-techne.com/1aa472?token...

19.09.2025 22:26 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Get ready for #NSH2025! Join us to learn more about exciting advances in #RNAscope ISH technology and how it can enhance your translational, clinical laboratory and pathology workflows.
Be sure to visit us at #booth139 to #AdvanceYourRNAscopeISH
Learn more engage.bio-techne.com/63afee?token...

15.09.2025 22:38 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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We brought our @biotechne.bsky.social Spatial Biology Division commercial team together to explore opportunities for growth and how to deliver even greater value & support for our customers, enabling them to reveal new insights with our ACD and Lunaphore spatial portfolio. Truly Spatial!

12.09.2025 18:09 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Wow! Love this beautiful image! #ArtofRNAscope

28.08.2025 20:20 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Wonderful! Thank you for #AdvancingYourRNAscope with us

26.07.2025 02:24 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Another striking #RNAscope image, thank you for #AdvancingYourRNAscope with us!

26.07.2025 02:23 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Congratulations on this beautiful front cover image! Thank you for #AdvancingYourRNAscope

26.07.2025 02:21 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Wow! How beautiful! <3 thank you for #AdvancingYourRNAscope with us - this image demonstrates the #ArtofRNAscope beautifully!

26.07.2025 02:20 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Pioneering the gold standard #RNAscope ISH technology since 2011, ACD has been at the forefront of #spatial biology and #RNAscopeMultiomics
Strike it rich with our expanded menu of RNAscope probes now available on bio-techne.com
Learn more: www.bio-techne.com/reagents/rna...

19.06.2025 15:24 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Great publication @bbparis1984.bsky.social - nice use of RNAscope Multiplex Fluorescent assay also! Thank you for #AdvancingYourRNAscopeISH with us!

18.06.2025 16:46 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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In this excellent publication by Higgs,@cardiffuni.bsky.social in @plos.org #RNAscope Multiplex Fluorescent is used to identify Magel2 in Gal/Th and Gal/Calcr cells, showing that a novel imprinted gene impacts parental behavior. Read more: journals.plos.org/plosgenetics... #RNAscopeMultiomics

17.06.2025 19:09 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Yesterday we celebrated Father’s Day 2025 – the paternal power behind RNAscope Spatial Multiomics driving innovation and strategic direction to our #SpatialMultiomic RNAscope portfolio.
bio-techne.com/reagents/rna...
#AdvancingYourRNAscopeISH #RNAscopeMultiomics #FathersDay2025 #SpreadtheWord

16.06.2025 16:19 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0