's Avatar

@subletterdave

33
Followers
62
Following
2
Posts
13.01.2025
Joined
Posts Following

Latest posts by @subletterdave

How Sup35 monomer conformation and amyloid fibril polymorphism determine yeast strain phenotypes In the [PSI+] prion system, the yeast prion protein Sup35 can form structurally distinct amyloid fibrils that lead to distinct transmissible prion states, or strains. However, our understanding of how...

Our new pre-print is out! The result of a wonderful collaboration with the Tanaka lab at RIKEN Center for Brain Science.

We investigate the question: what can yeast prions teach us about the connection between amyloid polymorphism and phenotype?

www.researchsquare.com/article/rs-7...

03.11.2025 22:17 👍 1 🔁 0 💬 0 📌 0
Preview
Protect the integrity of the US National Institutes of Health Letter to the Editor

These members of the NIH Council of Councils are voicing serious concerns about NIH grant terminations, restructure, and budget cuts

go.nature.com/46Vr8t2

23.07.2025 12:03 👍 66 🔁 36 💬 1 📌 7
Preview
Earlier Detection of Alzheimer’s Could Help Reduce Its Most Devastating Effects Heidi Jacobs, PhD, is a leader in Alzheimer’s disease research whose personal experience with the disease strengthens her passion for finding a cure — something she is well on her way to achieving.

Learn about our work towards earlier detection of Alzheimer's disease. Despite NIH-funding being delayed, terminated, and uncertain, we are fiercely committed to these goals! Link for donations to support our work is at the bottom of the page, or reach out.
giving.massgeneral.org/stories/earl...

23.07.2025 23:24 👍 18 🔁 4 💬 0 📌 0
Preview
Funding crisis hits US ageing research - Nature Shortfalls hamper scientists' efforts to address a predicted epidemic of age-related diseases.

More than a decade-old story, but it resonates again now.
"NIA is in an exceptional predicament. In recent years, it has made big commitments to costly clinical trials and large group projects."
www.nature.com/articles/468...
The value of top-down big projects needs to be reevaluated, especially now

20.07.2025 22:47 👍 3 🔁 1 💬 1 📌 0
Post image

I believe in fairness and an end to Big Money in politics.

Was one of the 36,000 ppl at the largest ever Sanders rally and was not paid to be there 😉

13.04.2025 07:27 👍 1 🔁 0 💬 0 📌 0