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Marc Perry

@mdperry

Biochemist (by training), Geneticist (by osmosis), Bioinformatician (by experience). Possesses an extremely peculiar sense of humor/humour.

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19.12.2023
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Latest posts by Marc Perry @mdperry

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In #GENETICS, Ananthaswamy et al. used the #Celegans oocyte model to identify the functions of nucleosome remodeling and deacetylase (NuRD) complex in the repair of endogenous double-strand breaks and exogenous DNA lesions. buff.ly/gFOnT8H

09.02.2026 21:01 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1
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Early resolution of sister chromatids during #Celegans #meiosis. New study from Antonia Hamrick and Ofer Rog @theroglab.bsky.social @uofubiology.bsky.social: rupress.org/jcb/article/...

#Chromatin #epigenetics #Genetics #CellCycle #CellDivision

10.02.2026 21:02 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

That poor man, he’s probably still crying himself to sleep every night. I hope he’s seeking help and not spiralling down into PTSD. Can you even imagine not getting what you spent your whole life assuming you deserved (just because you have a penis (well Y chromosome)?

11.02.2026 14:05 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

IN 1988 I STARTED MY POST-DOC IN BOULDER. FIRST E-MAIL ACCT SINCE UG AT CAL (CS COURSE ONLY). MY DAD WORKED AS CIVILIAN FOR THE NAVY AND WAS ON DARPANET. PREVIOUSLY HE’D SENT ~ 1 SNAILMAIL/5 YRS. SUDDENLY HE WAS WRITING ME ALL THE TIME LIKE THIS (ALL CAPS). WTF?!? YMMV

11.02.2026 14:00 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Pixie the Elf writes Perl Pixie the Elf is a cheerful Perl hacker at the North Pole. This page collects all of her Perl Advent calendar stories in one place.

I've been writing Advent Calendar posts about Pixie the Elf for a few years now. So I thought it was time she had her own website.

pixie.perlhacks.com

03.12.2025 12:23 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Immolation in the flame of an EtOH burner is a leading cause, as is being cut in half during data collection for an aging study.

26.11.2025 19:14 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

I've always loved the openness and collegiality of our C. elegans community πŸͺ±, but this perspective really helps emphasize just *how important* those traits are for scientific progress. A true tribute to how curiosity-driven science leads to innovation! πŸ™Œ

26.11.2025 15:01 πŸ‘ 22 πŸ” 9 πŸ’¬ 1 πŸ“Œ 0

Wait, if I just liked this chapter (verse?) will that spawn future chapters? Those cookies sound delicious. We saw Derek Jacobi live in a non-stuttering role in Toronto in the late 90’s.
What have you done with the real Ian Holmes? Is he even monitoring this bot?

18.11.2025 19:38 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

Wow! This looks fascinating

24.10.2025 06:34 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

A potent and plain-spoken defence of DEI in science - from the experts. Representation *matters*.

23.10.2025 22:03 πŸ‘ 33 πŸ” 19 πŸ’¬ 2 πŸ“Œ 0

(Voice of Mr. Rogers) β€œCan you say Nosferatu? Sure you can(!)” #twilight

07.10.2025 14:18 πŸ‘ 20 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Well obvs he is one hot MAGA warrior [this is sarcasm]. Facts: he is (a) overly full of himself, (b) delusional, (c) a Josef Goebbels doppelgΓ€nger, (AND wannabe). I don’t think he’ll be happy until he incites an armed revolt and then gets to call in air strikes on tenement slums. (IMHO)

07.10.2025 14:15 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Groundbreaking quantum-tunnelling experiments win physics Nobel John Clarke, Michel Devoret and John Martinis discovered quantum physics on a macroscopic scale, paving the way for quantum computing.

John Clarke, Michel Devoret and John Martinis have been awarded the 2025 Nobel Prize in Physics for demonstrating quantum physics on the macroscopic scale, which has paved the way for quantum computing. βš›οΈπŸ§ͺ

07.10.2025 14:08 πŸ‘ 15 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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Today’s NYT Spelling Bee Puzzle seems replete with answers for a former #celegans #genetics fan . . .

07.10.2025 14:11 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Are you an early career scientist who wants to get specialist training in C. elegans model for your laboratory research? we co-organize again the EMBO C. elegans course! Do not miss applying!

05.10.2025 13:38 πŸ‘ 6 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0

Pervasive homeobox gene function in the male-specific nervous system of Caenorhabditis elegans

journals.biologists.com/dev/article/...

27.08.2025 20:56 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Fun fact: diluted tattoo inks and washes make pretty decent carbon sources for NTMs.

22.08.2025 21:11 πŸ‘ 9 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

You had me at "supergiant cannibals." 😱 Gotta love the world of ciliates. GoodπŸ§΅β¬‡οΈ

26.08.2025 23:38 πŸ‘ 7 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
My Guilty Perl Obsession Perl came for free. How much have I contributed in return? Absolutely nothing.

As a member of the Toronto Perl Mongers I volunteered at the TPRC held in Toronto in 2023. This blog post from Bryan Katz relates his experience with Perl in general, and specifically at that conference #relatable #perl
www.perl.com/article/my-g...

26.08.2025 17:44 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Dynamic Birth and Death of Argonaute Gene Family Functional Repertoire Across Caenorhabditis Nematodes Abstract. Diverse small RNA pathways, composed of Argonaute effector proteins and their bound small RNA molecules, define critical systems for regulating g

Exciting new study showing extensive Argonaute protein family gain, loss, neofunctionalization + more among species, by PhD student Daniel Fusca with @katjakasimatis.bsky.social + Hongyu Zhu; Now out @genomebiolevol.bsky.social #celegans #rna doi.org/10.1093/gbe/...

12.06.2025 02:03 πŸ‘ 29 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0

Roundworms = nematodes
Flatworms = platyhelminths
Segmented worms = annelids
Have they changed this system of classifying types of worms since the late 1970s (when I learned it/them)?
Next you’ll be telling us Pluto is no longer a planet and that birds are just a type of reptile.

15.06.2025 23:32 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Not again?!?

15.06.2025 23:22 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Pervasive homeobox gene function in the male-specific nervous system of Caenorhabditis elegans https://www.biorxiv.org/content/10.1101/2025.05.13.653874v1

18.05.2025 00:03 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Alternative splicing across the C. elegans nervous system - Nature Communications By affecting which form of a gene is expressed, alternative splicing is a major source of diversity in the nervous system. Here, the authors present an atlas of splice variants across neurons, and exp...

Alternative splicing across the C. elegans nervous system

www.nature.com/articles/s41...

18.05.2025 01:02 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Whoah!!

18.05.2025 15:07 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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The Provisional Mortality statistics have been updated by the Australian Bureau of Statistics (ABS), up to January 2025.

Here are the deaths where the underlying cause of death was certified by a doctor as COVID-19 (22,357 deaths).
#COVID19 #Australia
🧡

18.05.2025 10:26 πŸ‘ 72 πŸ” 29 πŸ’¬ 4 πŸ“Œ 4

The US has cut the equivalent of 3X the total annual CIHR budget so far this year, revealing both how low the CIHR budget is and how utterly draconian the White House has treated one of the most precious and successful institutions the US has ever built.

13.05.2025 22:29 πŸ‘ 22 πŸ” 11 πŸ’¬ 2 πŸ“Œ 0

Huge thanks to Federico Gueli for his tips on new lineages to watch out for, eg
bsky.app/profile/siam...
🧡

10.05.2025 09:19 πŸ‘ 10 πŸ” 2 πŸ’¬ 1 πŸ“Œ 1
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With the LP.8.1.* variant dominant from the global perspective, it is time to ponder which variant might drive the next wave.

The leading contenders at this point are XDV.* (led by NB.1.8.1), and XFG.*.
#COVID19 #NB_1_8_1 #XFG
🧡

10.05.2025 09:19 πŸ‘ 63 πŸ” 24 πŸ’¬ 2 πŸ“Œ 3

@augustorendon.bsky.social It was such a good idea now everyone is copying you. Who knew?

10.05.2025 19:53 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0