Aakanksha Singhvi's Avatar

Aakanksha Singhvi

@singhvilabglia

Associate Prof @Fred Hutch (+ @UW_NBio) Glia fascinate me. Worms are rad. singhvilab.org

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08.11.2024
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Latest posts by Aakanksha Singhvi @singhvilabglia

This is so cool! Congratulations @krishnanyamuna.bsky.social and Krishnan lab team!!

20.12.2025 05:39 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

Closing out my year with a journal editor shocker 🧡

Checking new manuscripts today I reviewed a paper attributing 2 papers to me I did not write. A daft thing for an author to do of course. But intrigued I web searched up one of the titles and that's when it got real weird...

19.12.2025 17:20 πŸ‘ 2384 πŸ” 1224 πŸ’¬ 69 πŸ“Œ 358

On my list!! Excited to watch Flash, Flash, doing a hundred yard dash!!

06.12.2025 08:10 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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From nematode to Nobel: How community-shared resources fueled the rise of Caenorhabditis elegans as a research organism | PNAS Experimental organisms such as the nematode Caenorhabditis elegans are fundamental to biological discovery. The success of C. elegans research has ...

C. elegans researchers were early adopters of open science: "The development of common resources and the belief that research findings and mutant strains should be freely shared has propelled worm research to the forefront"
www.pnas.org/doi/10.1073/...

28.11.2025 08:00 πŸ‘ 21 πŸ” 13 πŸ’¬ 1 πŸ“Œ 1
PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

The open source spirit of the worm community makes it so special - and so powerful for discovery! Great account of the impact of the community tools and databases had and have on understanding fundamental biology! πŸͺ± www.pnas.org/doi/10.1073/...
Important to keep these resources funded!

26.11.2025 08:13 πŸ‘ 7 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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210K views Β· 5.7K reactions | Throwback to 2018 when physics laureate Donna Strickland started her banquet speech by talking about Cyndi Lauper's song 'Girls Just Want To Have Fun'. Strickland told ... Throwback to 2018 when physics laureate Donna Strickland started her banquet speech by talking about Cyndi Lauper's song 'Girls Just Want To Have Fun'. Strickland told us how enjoyable she found...

Yes, lab life is truly so much fun! So nicely said by Donna Strickland: www.facebook.com/reel/8264683...

23.11.2025 20:58 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Congratulations!!

11.11.2025 09:09 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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If said women work for your competitors, I guess maybe

06.11.2025 18:46 πŸ‘ 49 πŸ” 8 πŸ’¬ 1 πŸ“Œ 0

Reaffirming the value of model organisms in training scientific minds @ishmailsaboor.bsky.social exactly what we were talking about re your #Celegans background setting you up for creative work in other systems! www.nature.com/articles/s41...

11.10.2025 18:44 πŸ‘ 21 πŸ” 6 πŸ’¬ 1 πŸ“Œ 1
Photo: Cecilia Odlind

Photo: Cecilia Odlind

The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body πŸ§ͺ www.nobelprize.org/prizes/medic...

06.10.2025 09:41 πŸ‘ 110 πŸ” 33 πŸ’¬ 3 πŸ“Œ 5
Rhythmic metabolites in the E19 SCN peak during the day. Majority of rhythmic lipids and polar metabolites in the E19 SCN peak during the day, while there are more diverse phase clusters in the developed P28 SCN postweaning. Polar metabolites and lipids identified as rhythmic in E19 SCN (E19 clusters 1, top, and 2, bottom) were divided into subgroups based on hierarchical K-means clustering. Line plots on the left show traces of the normalized level of each rhythmic compound in each corresponding cluster. Bar plots on the right represent the lipid classes and polar metabolites in each rhythmic cluster.

Rhythmic metabolites in the E19 SCN peak during the day. Majority of rhythmic lipids and polar metabolites in the E19 SCN peak during the day, while there are more diverse phase clusters in the developed P28 SCN postweaning. Polar metabolites and lipids identified as rhythmic in E19 SCN (E19 clusters 1, top, and 2, bottom) were divided into subgroups based on hierarchical K-means clustering. Line plots on the left show traces of the normalized level of each rhythmic compound in each corresponding cluster. Bar plots on the right represent the lipid classes and polar metabolites in each rhythmic cluster.

How are #circadian rhythms established during development? This study shows that maternal metabolic signals oscillate in the fetal #SCN before the endogenous #clock becomes functional, offering a plausible mechanism for maternal entrainment of the developing clock @plosbiology.org πŸ§ͺ plos.io/3VD45fZ

29.09.2025 16:58 πŸ‘ 11 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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What if NIH had been 40% smaller? Replaying history with less NIH funding shows widespread impacts on drug-linked research

This may be the most important paper ever published about NIH funded research.

www.science.org/doi/10.1126/...

25.09.2025 21:19 πŸ‘ 413 πŸ” 250 πŸ’¬ 5 πŸ“Œ 19

Congratulatioms, @needhibhalla.bsky.social !!

20.09.2025 07:01 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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In situ Proteomics Unveils Specialized Domains for Extrasynaptic Signaling on Neuronal Cilia Neuronal cilia have emerged as crucial signaling hubs, yet their molecular composition and integration with synaptic communication remain poorly understood. Using a newly developed Arl13b-TurboID mous...

Whoa - neuronal ciliary proteome! Tons to dig into here - different from kidney cilia proteome (perhaps unsurprising) and enriched for many postsynaptic proteins, strengthening previous suggestions of cilia as postsynaptic signaling structures.
@nachury.bsky.social
www.biorxiv.org/content/10.1...

13.09.2025 18:49 πŸ‘ 74 πŸ” 19 πŸ’¬ 2 πŸ“Œ 1
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Thrilled to share our new paper @cp-cell.bsky.social:
β€œMicroglia–astrocyte crosstalk regulates synapse remodeling via Wnt signaling.”

This work demonstrates the necessity of glia–glia communication and coordination during synapse remodeling.

πŸ”— www.cell.com/cell/fulltex...

Faust et al., Cell 2025

12.09.2025 13:21 πŸ‘ 67 πŸ” 26 πŸ’¬ 12 πŸ“Œ 1

Happy Anniversary! πŸŽ‰

04.09.2025 07:59 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

A friendly reminder that the NIH Public Access Policy IS NOT β€œyou must publish open access” but rather β€œyou must ensure your copy of your paper is deposited into PubMed Central.”

Yes, it is very confusing. Yes, you should be able to do that deposit yourself without paying anything to a journal.

20.08.2025 16:33 πŸ‘ 81 πŸ” 35 πŸ’¬ 5 πŸ“Œ 3
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Extracellular vesicles aid in the transfer of long-term associative memory between Caenorhabditis elegans Memory formation is necessary for the survival of animals across phyla. Here, we elucidate the mechanism underlying the formation of long-term associative memory (LTAM) formed by treating Caenorhabdit...

The first one is some crazy work by @monmitabhar.bsky.social, Tanumoy, @hari-flies.bsky.social and Kamal Kishore. They eavesdropped on worm conversations and found the exciting phenomenon of movement of memory from one worm to another 2/n www.biorxiv.org/content/10.1...

27.02.2025 12:28 πŸ‘ 24 πŸ” 6 πŸ’¬ 5 πŸ“Œ 3

Congratulatioms @kavita-babu.bsky.social @monmitabhar.bsky.social and team! Super cool story!

21.08.2025 05:38 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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πŸ“£ Calling all early career #neuroscientists!
@thetransmitter.bsky.social & Neuromatch are teaming up to better understand how to support #EarlyCareer Researchers. Whether you're a student, postdoc, or launching your career, we want to hear from you.
➑️ www.thetransmitter.org/early-career...

18.08.2025 07:01 πŸ‘ 11 πŸ” 8 πŸ’¬ 0 πŸ“Œ 1

Yay-fab news, congratulations, Needhi!

07.08.2025 17:54 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Mapping molecules of an unsung brain cell Fred Hutch researchers have created a gene-expression map of glial cells of the tiny worm, C. elegans, adding the missing component that completes for the first time an atlas of the entire nervous sy...

Fred Hutch researchers created a gene-expression map of glial cells in tiny worms, adding the missing component that completes an atlas of the entire nervous system of a multicellular adult animal at the molecular level. @singhvilabglia.bsky.social @manusetty.bsky.social bit.ly/47353c3

29.07.2025 19:51 πŸ‘ 4 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

Great opportunity here to build your skills and your professional network! Apply for the SciComm Interns program!
#devbiolwriteclub
@socdevbio.bsky.social

29.07.2025 18:15 πŸ‘ 9 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
Society for Developmental Biology | Strategic Planning Internship

Interested in science administration? Want to meet and work with senior members of the SDB? Want to help chart the future of the SDB? Then apply for the Strategic Planning Internship!
@socdevbio.bsky.social

www.sdbonline.org/strategic_pl...

29.07.2025 18:23 πŸ‘ 5 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

fantastic work from @melcooperphd.bsky.social - what are these beautiful networks doing in our brains?

22.07.2025 20:08 πŸ‘ 26 πŸ” 4 πŸ’¬ 0 πŸ“Œ 1
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Assistant Professor of Biology, Tenure Track Department Biology Vassar College is dedicated to providing equal employment opportunities to all applicants and employees and welcomes applications from individuals of all backgrounds. Decisions conc...

Vassar College is seeking a biologist with a focus on Developmental Neurobiology on the tenure-track. Please spread widely!

vassar.wd1.myworkdayjobs.com/en-US/Vassar...

17.07.2025 20:01 πŸ‘ 27 πŸ” 41 πŸ’¬ 0 πŸ“Œ 0
Assistant Professor - Biology Click the link provided to see the complete job description.

🚨🚨🚨PUI TT Job Alert!!

My dept at TCNJ is hiring a tenure track cell and molecular biologist. Come join my supportive colleagues, helpful staff, & fabulous students!

We're surprisingly well resourced w/excellent equipment (confocal, SEM etc) and research w/students counts towards our teaching load!

17.07.2025 21:45 πŸ‘ 75 πŸ” 82 πŸ’¬ 4 πŸ“Œ 4

Many congratulations!

16.07.2025 01:27 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

How cool - Congratulations @sciencenlucia.bsky.social!!

16.07.2025 01:24 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Congratulations, and best wishes @eblancosuarez.bsky.social !

16.07.2025 01:22 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0