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ICB - the journal

@immunolcellbiol

Cutting edge original research, provocative and exciting reviews and News and Commentary coverage on Immunology and Cell Biology

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Latest posts by ICB - the journal @immunolcellbiol

July's featured article from our exchange with @discovimmunol.bsky.social investigates the immunomodulatory capacity of various arginine-related metabolites.

academic.oup.com/discovimmuno...

18.07.2025 08:32 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

This is a great new study showing in Crohn’s disease, aphthous ulcers trigger immune responses via bacterial uptake, not dysbiosis

This is part of the article exchange between the BSI's @discovimmunol.bsky.social and the @immunolcellbiol.bsky.social

20.06.2025 10:30 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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This month’s article exchange with @immunolcellbiol.bsky.social:

New study shows that in Crohn’s disease, aphthous ulcers trigger immune responses via bacterial uptake, not dysbiosis.

Peyer’s patches may be the ignition site 🧬

Read here: doi.org/10.1111/imcb...

#Crohns #Immunology

20.06.2025 09:16 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1

What can we learn about airway resident memory T cells from pig models? Plenty! Find out more in this month's @discovimmunol.bsky.social Outstanding Article

19.06.2025 08:48 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1

For this month’s article exchange with @immunolcellbiol.bsky.social: Genetic analysis causally links 22 immune cell types to PCOS. Blood metabolites mediate several effects, offering new insight into how immunity and metabolism shape disease.

πŸ”— doi.org/10.1111/imcb...

22.05.2025 11:15 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

May's featured article in our exchange with @discovimmunol.bsky.social reveals altered spatial distribution of ILCs in #endometriosis and suggests the primary role of uterine ILC3 may be endometrial repair and regeneration.

22.05.2025 10:33 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library In this article for the Highlights of 2024 series, we review the latest advances in the biology of the germinal center response. These discoveries provide key insights into germinal center function a...

Our @immunolcellbiol.bsky.social "Highlights of 2024: Germinal Centers" is now out. Led by Theresa Pankhurst, we discuss some (there's never enough space for all!) neat germinal centre papers that were published in 2024, and whose findings are moving the field forward. doi.org/10.1111/imcb...

22.05.2025 00:13 πŸ‘ 21 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library This study examines how Notch signaling conditions the genome landscape within activated CD8+ TΒ cells in such a way to alter the binding pattern of transcription factors such as Gata3. This NotchΒ dep...

For this month's article exchange with @immunolcellbiol.bsky.social we're highlighting "Notch dependent chromatin remodelling enables Gata3 binding and drives lineage specific CD8+ T cell function."

A study on how Notch signalling primes antiviral CD8+ T cell responses.

πŸ“– doi.org/10.1111/imcb...

24.04.2025 14:21 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Our April article exchange with @discovimmunol.bsky.social features a study on the relative contribution of CD28 and TCR signals on human naive and memory T cells.
academic.oup.com/discovimmuno...

24.04.2025 08:38 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library The Sensory Science exhibition, held during March 2024, was a collaborative effort between researchers and artists, aimed to promote the importance of inclusive and diverse scientific engagement for ....

Great new article out led by @stevipiliou.bsky.social on improving accessibility to neuroimmunology for the blind and low-vision communities! @immunolcellbiol.bsky.social

onlinelibrary.wiley.com/doi/10.1111/...

18.04.2025 14:46 πŸ‘ 7 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library Amy Wilson, a Research Advisor for the Ovarian Cancer Research Foundation (OCRF) and an Honorary Research Associate at the Hudson Institute of Medical Research, began her career as a postdoctoral res....

"Your career is more than just your technical expertiseβ€”the skills, interests and motivations that make you unique, both inside and outside of research, can shape your path in unexpected ways."

Dr Amy Wilson from @ocrfaustralia.bsky.social reflects on moving into a research advisor role

21.03.2025 02:37 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library Bone marrow ablation and reconstitution are commonly used procedures in research that are often associated with significant suffering for the animals involved, classified as β€˜severe’, Category E or C...

For this month's article exchange with
@immunolcellbiol.bsky.social, we're highlighting 'Refining bone marrow ablation and reconstitution in mice.' by Penny Hawkins, James Dooley, Jessica Rodda and Colin Gilbert.

πŸ”Ž Read here: doi.org/10.1111/imcb.12847

20.03.2025 17:15 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

To what extent do different practices of microbial exposure affect resulting mouse phenotypes? March's Outstanding article from @discovimmunol.bsky.social shows a side-by-side comparison, enhancing understanding of naturalisation model setups and effects on the gut barrier and immune system

20.03.2025 07:40 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library In this manuscript for the β€œHighlights of 2024” series, this is me trying to summarize recent discoveries regarding the emerging regulatory and effector roles of Ξ³Ξ΄ TΒ cells during sepsis, both in hum....

Are you ready for it?

"Highlights of 2024: Ξ³Ξ΄ T cells and bad blood"

A summary of the emerging regulatory and effector roles of #gdTcells in #sepsis.

And it may also contain a few Taylor Swift references. More than 50 in fact.

Thank you so much @immunolcellbiol.bsky.social for playing along!

10.03.2025 00:29 πŸ‘ 38 πŸ” 16 πŸ’¬ 6 πŸ“Œ 3
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library In this article, we discuss the conceptualization, formation and management of our workplace Parents Group. We honestly reflect on both our successes and challenges. Graphic from Vivienne Samson (age....

From pipettes to playdates! @rhea-longley.bsky.social et al. share challenges and successes from establishing a parent support group in a research setting.

07.03.2025 04:53 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library Click on the title to browse this issue

Coinciding with #InternationalWomensDay, this special feature explores persistent barriers from gender pay gaps to underrepresentation in leadership and global strategies for change, not only for women but all marginalised groups in healthcare and STEMM.

07.03.2025 03:26 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
In this graphic, the words diversity, equity and inclusion are shown above cartoons of five scientists/healthcare professionals. Below are cartoon antibodies, and the words healthcare and stem.

In this graphic, the words diversity, equity and inclusion are shown above cartoons of five scientists/healthcare professionals. Below are cartoon antibodies, and the words healthcare and stem.

Our new special feature is out now! From reflections on starting a parents group for researchers to a case study on Indigenous student engagement in science, this special feature amplifies intersectional discussions on diversity, equity, and inclusion in healthcare and STEMM. bit.ly/41JpXKa

07.03.2025 03:25 πŸ‘ 4 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library This article highlights the work of our trainee-led organization, Immunologists for Gender Equity (IgEquity), which addresses gender inequities in Immunology through initiatives focused on community ....

This article from our upcoming special feature on Advancing Equity and Inclusion in Healthcare highlights the work of Immunologists for Gender Equity (IgEquity), a trainee-led organisation at @immunox.bsky.social. #InternationalWomensDay

05.03.2025 23:38 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Our paper is finally out in @immunolcellbiol.bsky.social, think that transcription factor expression is all that? Well not if the genome is not prepared in a way to allow binding: here is a short 🧡1/

01.03.2025 02:34 πŸ‘ 18 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0

For this month's article exchange with @immunolcellbiol.bsky.social, we're highlighting 'Exploring the dynamics of T-cell responses: a combined approach using EdU incorporation and proliferation dye dilution assay' by @jfreenvanheeren.bsky.social and colleagues

πŸ”Ž Read here: doi.org/10.1111/imcb...

20.02.2025 14:11 πŸ‘ 6 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1

Obesity is associated with increased susceptibility to infection, which may be due to obesity-induced immune dysregulation. The latest article exchange highlight from @discovimmunol.bsky.social looks at dendritic cell responses to Sendai Virus in a mouse model of diet-induced obesity.

20.02.2025 06:14 πŸ‘ 8 πŸ” 5 πŸ’¬ 0 πŸ“Œ 1
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library In this article, we identify self-reactive peripheral blood B cells in SjΓΆgren's disease through a single-cell culture system. We find 2- to 10-fold increased frequencies of self-reactive B cells dur...

Self-reactive B cells are increased in all major stages of peripheral development in SjΓΆgren's disease. This study from Lee et al. suggests that depleting self-reactive B cells based on B cell receptor specificity would be more efficient than targeting developmental stage in SjΓΆgren's disease.

18.02.2025 03:57 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thanks @immunolcellbiol.bsky.social for inviting Menno and I to write this commentary about the @bogunoviclab.bsky.social paper in @nature.com on monoallelic allele expression in inborn errors of immunity
Monash Immunology and
Erasmus MC #immunosky
doi.org/10.1111/imcb...

06.02.2025 07:26 πŸ‘ 6 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

If any American immunologists want to write an op-ed for @immunolcellbiol.bsky.social on the impact of the new executive orders, please contact me

03.02.2025 10:05 πŸ‘ 13 πŸ” 8 πŸ’¬ 1 πŸ“Œ 0
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library In this study, we investigated multiple cytokine combinations to boost natural killer (NK) cell proliferation as well as effector functions of proliferated NK cells against hepatocellular carcinoma a...

Modeling the response to interleukin-21 to inform natural killer cell immunotherapy

03.02.2025 02:40 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Also, the submission and editorial experience with @immunolcellbiol.bsky.social was fantastic, highly efficient, very professional, and yes I am an #AusNZSocImmunol member, but if you are looking for somewhere to publish #immunologyiscool work, can't recommend highly enough.

30.01.2025 23:01 πŸ‘ 2 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

Thanks for the shout out @sjturn.bsky.social – looking forward to seeing your lab's new paper out soon!

31.01.2025 01:21 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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So many good reasons to publish in ICB!

30.01.2025 02:36 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library This manuscript, part of the Special Series β€œFocus on South American immunology”, provides a personal reflection on the challenges and opportunities I have encountered during my journey as an immunol...

Ten years away from β€œhome” as a South American immunologist in Ireland: Dr Natalia MuΓ±oz-Wolf shares insights on pursuing an international scientific career in this #ImmunologyFutures article

28.01.2025 23:22 πŸ‘ 5 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library In this study, we investigated the longitudinal dynamics and clonal expansion of circulating Ξ³Ξ΄ TΒ cells in four patients receiving anti-CD19 CAR-T cell therapy. Using single cell multi-omics analysis....

As part of our article exchange with @immunolcellbiol.bsky.social, this month we're highlighting the article 'Identification of clonally expanded Ξ³Ξ΄ T-cell populations during CAR-T cell therapy'

Read the article exploring immune response after anti-CD19 #CAR-T therapy here: doi.org/10.1111/imcb...

23.01.2025 14:49 πŸ‘ 8 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1