Veronica Dezi

In case you missed it, our 2025 review on the BCL-2 protein family summarises the field from discovery to drug development

The BCL-2 protein family: from discovery to drug development
Read here: rdcu.be/e6MVA

What drugs are safe during pregnancy? There’s a shocking lack of data Drug trials have typically excluded pregnant people for safety reasons. But that’s now starting to change.

What drugs are safe during pregnancy? There’s a shocking lack of data www.nature.com/articles/d41...

Beyond the canon: emerging modalities of regulated cell death - Cell Death & Differentiation Cell Death & Differentiation - Beyond the canon: emerging modalities of regulated cell death

www.nature.com/articles/s41...

Why ADHD goes undiagnosed in girls Differences in how the condition presents in girls, and co-occurring psychiatric conditions, make detection more difficult.

Why ADHD goes undiagnosed in girls www.nature.com/articles/d41...

Functional characterisation of tumour suppressor PDCD4 reveals previously undisclosed role in the control of cell adhesion Abstract. PDCD4 is a multifunctional RNA-binding protein that has tumour suppressor function. To more fully understand how dysregulation of this protein co

I am excited to share our latest publication in @narjournal.bsky.social 🤩 Thanks to everyone who made this possible @mrc-tu.bsky.social

Functional characterisation of tumour suppressor PDCD4 reveals previously undisclosed role in the control of cell adhesion url: academic.oup.com/nar/article/...

SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade - Nature mRNA vaccines targeting SARS-CoV-2 also sensitize tumours to immune checkpoint inhibitors.

www.nature.com/articles/s41...

Artificial intelligence for breast cancer prevention: the vision ahead - European Radiology Abstract Over the past decade, artificial intelligence (AI) has entered the medical field, particularly in radiology. Fifty years after the transition from “silver to silicon”, we are experiencing a s...

link.springer.com/article/10.1...

A drug–diet combination could improve childhood cancer treatment Mouse studies show that depriving neuroblastoma of certain amino acids causes a switch in protein synthesis to suppress tumour growth and promote cell differentiation.

www.nature.com/articles/d41...

Only Humans can add:
Contextual understanding
Ethical judgment
Empathy and tone
www.springernature.com/gp/advancing...

BoobyBiome Raises £2.5M to Preserve Breast Milk’s Hidden Microbiome | Femtech Insider When Dr. Sioned Jones and her co-founders were collecting breast milk samples for their research at UCL, they made an accidental discovery that would reshape their entire business strategy. The London...

femtechinsider.com/boobybiome-r...

Lithium deficiency and the onset of Alzheimer’s disease - Nature Lithium has an essential role in the brain and is deficient early in Alzheimer’s disease, which can be recapitulated in mice and treated with a novel lithium salt that restores the physiological level...

www.nature.com/articles/s41...

AstraZeneca pauses £200m investment in Cambridge research site Decision means none of drugmaker’s much-trumpeted £650m UK investment package is currently proceeding

www.theguardian.com/business/202...

Polysome sorting controls mRNA localization and protein fate RNA localization and local translation are widespread phenomena that play key roles in a plethora of cellular processes ranging from embryo patterning to general cellular functions. The traditional pa...

Polysome sorting controls mRNA localization and protein fate: Trends in Cell Biology www.cell.com/trends/cell-...

Consumers question safety of parabens and PFAS in personal care products amid health concerns Growing research into cosmetic ingredients has been raising safety concerns among consumers. Bárbara Pinho explores the future of safer chemistry amid the 'clean beauty' trend

www.chemistryworld.com/features/con...

#stress #pregnancy #pediatric #eczema #nature #immunology #neuroimmunology #maternalhealth #atopicdermatitis #pediatricresearch | Nicolas Gaudenzio | 17 comments 🧬 Maternal Stress & Pediatric Eczema (Paradigm Shift) I am particularly thrilled to share our new paper published in Nature Magazine, where we uncover a previously unknown mechanism linking maternal ...

www.linkedin.com/posts/nicola...

Promoter-targeted small RNA duplexes increase MBNL1 transcription and mitigate myotonic dystrophy-associated spliceopathy Abstract. Functional depletion of Muscleblind-like (MBNL) proteins is a key trigger of myotonic dystrophy (DM)-associated alternative splicing (AltS) defec

⭐NAR Breakthrough!⭐
🧬 New study shows that small activating RNAs can boost MBNL1 expression in #myotonicdystrophy cells, restoring splicing balance. This highlights #RNAactivation (RNAa) as a promising #therapeutic strategy for this #raredisease.
📖 doi.org/10.1093/nar/...
#NARBreakthrough

Is there a place for AI in research assessment? - Impact of Social Sciences AI is reshaping research, from drafting proposals and academic CVs to automating parts of peer review and assessment. With efforts to reform research assessment in motion, Elizabeth Gadd and Nick Jenn...

“Human judgement first, and technology in support” blogs.lse.ac.uk/impactofsoci...

Age as a risk factor of autoimmunity.

A Perspective article, published in Nature Aging, discusses whether aging predisposes to autoimmunity, arguing that disease progression in the autoimmune vasculitis giant cell arteritis is driven by age-inappropriate sustenance of immune competence. go.nature.com/3UvrpvB🔒 🧪