@azusakage
Gravitational biologist, 助教 (PI) in Muroran, Hokkaido, Japan. Studying motility and behavior of microorganisms. bioconvection / gravitaxis / eukaryotic flagella / cilia / low Reynolds number / Chlamydomonas♉️ / Volvocales / Paramecium / protists🦠 / Python
New preprint alert! 🦠🔬
We quantitatively evaluated the swimming and flagellar movement of Chattonella, a red-tide alga.
Chattonella has two unequal flagella, and we found a positive correlation between anterior flagellum length and swimming speed. #protistonsky
www.biorxiv.org/content/10.6...
Our paper on dynein-2's track recognition mechanism is now published in The EMBO Journal @embojournal.org!!
Cryo-ET and MD simulations reveal that dynein-2 is tuned for binding to the A-tubule of the ciliary doublet | The EMBO Journal www.embopress.org/doi/full/10....
Excited to share that I've joined EABIAS (East Asia Bioimage Analysts’ Society) following the recent GloBIAS Bioimage Analysis Conference 2025!
Happy to be part of this community. よろしくお願いします＆請多指教！
eabias.org/about/
Safely back in Hokkaido! Had a wonderful time at #GloBIAS2025 in Kobe.
The atmosphere of mutual support was fantastic!
Huge thanks to everyone who interacted with me!
(Our university mascot, Muropyon, enjoyed the beautiful Kobe night view too! 🌃) #GloBIAS
Going to Kobe for GloBIAS Bioimage Analysis Conference 2025! A bit at a loss what to wear, as we're already using the heater here in Muroran, Hokkaido.🥶
#GloBIAS
Reposting our microPublication now indexed in PubMed:
We analyzed the movement of the unicellular green alga Chlamydomonas using #DeepLabCut, a deep learning-based tracking tool originally developed for animal behavior studies.
pubmed.ncbi.nlm.nih.gov/40331205/
Original videos: 🧵
#protistsonsky
Here is our set of videos capturing eukaryotic flagellar motion at 200 fps, including 46 live cells and 56 demembranated models of the Chlamydomonas uniflagellate mutant. #protistsonsky
zenodo.org/records/1509...
Reposting our microPublication now indexed in PubMed:
We analyzed the movement of the unicellular green alga Chlamydomonas using #DeepLabCut, a deep learning-based tracking tool originally developed for animal behavior studies.
pubmed.ncbi.nlm.nih.gov/40331205/
Original videos: 🧵
#protistsonsky
Spring in northern Japan🌸
Our analysis of the rotational movement of Chlamydomonas uniflagellar mutant using #DeepLabCut has just been published in microPublication Biology!
micropublication.org/journals/bio...
All video data (~100 individuals, both live cells and demembranated models) are available on Zenodo, so feel free to explore and reuse!
zenodo.org/records/1509...
#protistsonsky
Our analysis of the rotational movement of Chlamydomonas uniflagellar mutant using #DeepLabCut has just been published in microPublication Biology!
micropublication.org/journals/bio...
Oxygen gradients shape E. coli motility patterns as they run away from O2! - 😍
Asked similar question before but I try again. Anyone knows proteins that localize like this? This protein is present in diplonemids/bodonids/euglenids/Naegleria, which have two flagella, but not in trypanosomatids that have just one flagellum. Potentially interesting for flagella/cilia community?
We have posted our new #preprint regarding the track recognition mechanism of dynein-2 that works in #cilia on bioRxiv @biorxivpreprint.bsky.social!!
www.biorxiv.org/content/10.1...
1/8 🧵
Dynein-2 is tuned for the A-tubule of the ciliary doublet through tubulin tyrosination https://www.biorxiv.org/content/10.1101/2025.01.27.635025v1
Interesting. I’m not very familiar with Alphafold, so I didn’t know that.
It’s interesting that all versions of Alphafold distort large extended proteins to ‘globularise’ them. It’s fine for people that understand those helices are ‘bent’ but for non experts it’s confusing. 🫤 🤔 It happens a lot and isn’t well discussed in the community.
【青山たけしSNS】
いつもSNSをチェックいただき
ありがとうございます
Xでの発信をメインとしてますが
Instagramも
2000名近くの方に閲覧いただく
（Xとは若干内容が異なります）
Threadsに加えて新たに
Bluesky bsky.app/profile/aoyama…
をはじめました
今後も室蘭の情報発信を続けます
追加しました！
Proud to be part of this paper published in @naturecomms.bsky.social. Using high-speed AFM, we have visualized the real-time translocation of substrate polypeptide by the single molecule of SecYEG-SecA!!!
Please check this amazing video taken by high-speed AFM!!!
www.nature.com/articles/s41...
Happy New Year from the northside of Japan🌅🎍❄️
New Year decorations at our lab🎍
Did you know #diatoms are motile? These tiny glass cells have no cilia or flagella and a rigid body yet can glide on surfaces using a specialised slit in the cell wall called the raphe! What is the functional morphology of the raphe? All revealed in our new preprint
www.biorxiv.org/content/10.1...
International Society of Protistologists is funding two symposia at the 16th International Congress of Protistology in Seoul, South Korea. Proposals are due 30 January 2025
#protist #protistsonsky
protistologists.org/programs/fun...
🍾Our small #UExM adventure is only starting! #ProtistsOnSky
We are happy to announce that the Moore Foundation will be funding our efforts in creating an Expansion Microscopy atlas of #Microbial #Eukaryotes with @gautamdey.bsky.social @UNIGE
@embl.org
LINK: www.unige.ch/sciences/chi...
1/4
FlumeX: A Modular Flume Design for Laboratory-Based Marine Fluid-Substrate Studies
📢 Please re-share! New Preprint Alert -- in collaboration w/ @prannoysuraneni.bsky.social @coralprof.bsky.social and others @univmiami.bsky.social @miamirosenstiel.bsky.social
FlumeX: A Modular Flume Design for Laboratory-Based Marine Fluid-Substrate Studies @SSRN papers.ssrn.com/sol3/papers....
Joined #NewPISlack 👀
12月1日から、国立遺伝学研究所の所長として赴任しました近藤滋です。
日本の基礎科学を盛り上げるために、精一杯働く所存です。皆さん、ご協力をお願いいたします。
所長挨拶：
www.nig.ac.jp/nig/ja/about...
学生へのメッセージ：
www.nig.ac.jp/nig/ja/phd-p...
どちらも、楽しく読んでいただけるように書きました。特に、学生へのメッセージの方ができが良いので、まずそちらからお読みいただけますと幸いです。
For example, drafting a paper in your native language and using gen AI to translate it, or having gen AI check your English, etc
