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Stepped Wedgehog

@steppedwedgehog

Stepped Wedgehog (you won't be surprised to hear) posts on stepped wedge trials and related topics. Visit the website at https://steppedwedgehog.org.

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21.11.2024
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Latest posts by Stepped Wedgehog @steppedwedgehog

To streamline and focus all of this great work, the two conference streams will be joining forces from 2027 onwards to form a single International Conference on Cluster Randomised & Stepped Wedge Trials.

Watch this space!

03.02.2026 16:37 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The annual meeting on Current Developments in Cluster Randomised Trials & Stepped Wedge Designs was held most recently in Birmingham UK in 2025.
bsky.app/profile/step...

03.02.2026 16:37 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

πŸ“’The biennial York conference is open for another 10 days for submissions to its 2026 meeting:
bsky.app/profile/step...

03.02.2026 16:37 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

A super-engaged (and expanding) group of people around the world are doing thoughtful research on how to do stepped wedge trials better.

There are currently TWO regular conference streams (never let it be said that I hog all the stepped wedges):

03.02.2026 16:37 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Yes, I think the stepped wedge might catch on.

03.02.2026 16:37 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

A reminder that the call for abstracts for the 5th International Conference on Stepped Wedge Design 2026 is still openβ€”deadline 13th Feb midday.

21.01.2026 11:40 πŸ‘ 1 πŸ” 2 πŸ’¬ 1 πŸ“Œ 1
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Reported problems and responses during the conduct of stepped-wedge cluster randomized trials in healthcare settings: a qualitative systematic review AbstractBackground. The stepped-wedge cluster randomized trial (SW-CRT) is a pragmatic complex design that can be difficult to implement. We aimed to summa

Reported problems and responses during the conduct of stepped-wedge cluster randomized trials in healthcare settings: a qualitative systematic review academic.oup.com/ije/article/...

09.01.2026 09:34 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The stepped wedge design came up in the #CCRDownUnder meeting last week so it seemed a good time to revisit the pros and cons of this design 1/6
#MethodologyMonday #128

15.12.2025 08:05 πŸ‘ 13 πŸ” 6 πŸ’¬ 3 πŸ“Œ 1
Role of recruitment bias in stepped-wedge cluster randomised controlled trials: a systematic review Objectives Increased popularity of stepped-wedge cluster randomised trials (SW-CRT) highlights the importance of understanding and appropriate mitigation of sources of bias within this trial design. W...

Role of recruitment bias in stepped-wedge cluster randomised controlled trials: a systematic review bmjopen.bmj.com/content/15/1...

12.12.2025 10:14 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
A scoping review identified additional considerations for defining estimands in cluster randomised trials An estimand is a clear description of the treatment effect a study aims to quantify. The ICH E9(R1) addendum lists five attributes that should be described when defining an estimand. However, the adde...

A scoping review identified additional considerations for defining estimands in cluster randomised trials - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

19.10.2025 14:33 πŸ‘ 4 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

Lots of feedback and engagement after this session. Some gentle push-back still: "But what if there's even just a *perception* from sites that a stepped wedge is preferable?" 🧡

21.10.2025 15:39 πŸ‘ 9 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0

πŸ“’ Registration now open for the 11th annual meeting on Current Developments in Cluster Randomised Trials & Stepped Wedge Designs on 18th & 19th November 2025 in Birmingham UK.

shop.bham.ac.uk/conferences-...

25.09.2025 15:59 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Assessing Mediation in Cross‐Sectional Stepped Wedge Cluster Randomized Trials Mediation analysis has been studied for independent data, but relatively little work has been done for correlated data observed under stepped wedge cluster randomized trials (SW-CRTs). Motivated by t...

Assessing mediation in cross-sectional stepped wedge cluster randomized trials onlinelibrary.wiley.com/doi/10.1002/...

16.09.2025 08:49 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Save the date: Fifth International Conference on Stepped Wedge Design 2026 12th-14th May (online)

www.york.ac.uk/healthscienc...

12.09.2025 09:19 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1
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Information-Theoretic Criteria for Optimizing Designs of Individually Randomized Stepped-Wedge Clinical Trials - Statistics and Computing Clinical trials are essential for advancing medical knowledge and improving health care, with Randomized Clinical Trials (RCTs) considered the gold standard for minimizing bias and generating reliable...

Information-theoretic criteria for optimizing designs of individually randomized stepped-wedge clinical trials link.springer.com/article/10.1...

22.08.2025 13:05 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

A useful reminder of the original meaning of a "stepped wedge".

05.08.2025 12:21 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Grand rounds in methodology: improving the design of staggered implementation cluster randomised trials The stepped-wedge cluster randomised trial is a popular design in implementation and health services research. All clusters, such as clinics or hospitals, start in the control state, and gradually swi...

Improving the design of staggered implementation cluster randomised trials qualitysafety.bmj.com/content/earl...

05.08.2025 12:20 πŸ‘ 3 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Power calculation for cross-sectional stepped wedge cluster randomized trials with a time-to-event endpoint ABSTRACT. Stepped wedge cluster randomized trials (SW-CRTs) are a form of randomized trial whereby clusters are progressively transitioned from control to

Super happy to say that my first Biometrics article was published this week!πŸ˜ƒ Along with Fan Li, Monica Taljaard, & Denise Esserman, we derive sample size & power formula for cross-sectional stepped-wedge trials with time-to-event outcomes, & explored the impact of finite sample variance corrections

26.06.2025 14:05 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

Abstracts on any aspect of design, conduct, analysis and reporting of cluster and stepped-wedge trials are welcome, and the aim is for a balance of methodological and applied presentations.

13.06.2025 09:28 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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πŸ“’ The 11th annual meeting on Current Developments in Cluster Randomised Trials & Stepped Wedge Designs will take place 18/19 November 2025 in Birmingham UK.

Abstract submission is open, deadline for submission 11 July 2025 forms.gle/jS83TAKhs4U8.... Info on registration etc to follow!

13.06.2025 09:28 πŸ‘ 0 πŸ” 2 πŸ’¬ 1 πŸ“Œ 3

Well I'm definitely not.

15.05.2025 14:54 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Identifying Less Burdensome and More Cost‐Efficient Incomplete Stepped Wedge Designs for Continuous Outcomes Collected via Repeated Cross‐Sections Stepped wedge trials can be costly and burdensome. Recent work has investigated the iterative removal of cluster-period cells from stepped wedge designs, producing a series of candidate incomplete de...

Identifying less burdensome and more cost-efficient incomplete stepped wedge designs for continuous outcomes collected via repeated cross-sections onlinelibrary.wiley.com/doi/10.1002/...

08.05.2025 11:55 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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How Should Parallel Cluster Randomized Trials With a Baseline Period be Analyzed?β€”A Survey of Estimands and Common Estimators The parallel cluster randomized trial with baseline (PB-CRT) is a common variant of the standard parallel cluster randomized trial (P-CRT). We define two natural estimands in the context of PB-CRTs w....

How should parallel cluster randomized trials with a baseline period be analyzed?β€”a survey of estimands and common estimators onlinelibrary.wiley.com/doi/10.1002/...

30.04.2025 15:38 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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What Is a Stepped-Wedge Cluster Randomized Trial? This Guide to Statistics and Methods describes design, interpretation, and examples of a stepped-wedge cluster randomized trial.

What is a stepped wedge cluster randomized trial? jamanetwork.com/journals/jam...

11.03.2025 13:19 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Bayesian Hierarchical Penalized Spline Models for Immediate and Time‐Varying Intervention Effects in Stepped Wedge Cluster Randomized Trials Stepped wedge cluster randomized trials (SWCRTs) often face challenges related to potential confounding by time. Traditional frequentist methods may not provide adequate coverage of an intervention's ...

Bayesian hierarchical penalized spline models for immediate and time-varying intervention effects in stepped wedge cluster randomized trials pmc.ncbi.nlm.nih.gov/articles/PMC...

28.02.2025 09:22 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1
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Analysis of Cohort Stepped Wedge Cluster-Randomized Trials With Nonignorable Dropout via Joint Modeling - PubMed Stepped wedge cluster-randomized trial (CRTs) designs randomize clusters of individuals to intervention sequences, ensuring that every cluster eventually transitions from a control period to receive t...

Analysis of cohort stepped wedge cluster-randomized trials with nonignorable dropout via joint modeling pubmed.ncbi.nlm.nih.gov/39963907/

28.02.2025 09:19 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Sage Journals: Discover world-class research Subscription and open access journals from Sage, the world's leading independent academic publisher.

The relative efficiency of staircase and stepped wedge cluster randomised trial designs journals.sagepub.com/doi/full/10....

28.02.2025 09:17 πŸ‘ 0 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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A systematic review of stepped wedge cluster randomized trials in high impact journals: assessing the design, rationale, and analysis Stepped wedge cluster randomized trials (SW-CRTs) are an appealing study design because they enable sequential roll out of an intervention across clusters, bringing logistical advantages. This review ...

A systematic review of stepped wedge cluster randomized trials in high impact journals: assessing the design, rationale, and analysis www.jclinepi.com/article/S089...

24.01.2025 10:31 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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How nurse researchers can use stepped-wedge design and analysis How nurse researchers can use stepped-wedge design and analysis

How nurse researchers can use stepped-wedge design and analysis journals.rcni.com/nurse-resear...

16.01.2025 09:45 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Multilevel Intervention Stepped Wedge Designs (MLI-SWDs) - Prevention Science Multilevel interventions (MLIs) hold promise for reducing health inequities by intervening at multiple types of social determinants of health consistent with the socioecological model of health. In sp...

Multilevel intervention stepped wedge designs link.springer.com/article/10.1...

16.01.2025 09:42 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0