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David Pla Martin

@dplamartin

Professor @hhu_de Mitochondrial Biology 🧬 | Institute of Biochemistry and Molecular Biology I | mitochondria, mtDNA and mitophagy http://bit.ly/bumb1

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19.09.2023
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Latest posts by David Pla Martin @dplamartin

It looks great on the paper but you also mention it. I think it will be challenging to find people to β€œfreely” replicate another’s group experiments. That’s time and resources invested for almost no reward. Not sure if a citation as a peer replicator is worth the time and the effort

27.02.2026 15:51 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

I have the feeling that this will not work….

26.02.2026 07:12 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

To all #mitochondria lovers: Euromit 2026 early-bird registration is coming up!

11.02.2026 15:53 πŸ‘ 6 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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Hey, science community (whoever is here). Can you please help me amplify this message? Postdoc position available in DΓΌsseldorf!

05.01.2026 13:33 πŸ‘ 3 πŸ” 10 πŸ’¬ 0 πŸ“Œ 1
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Hallo @hhu.de, kΓΆnntest du mir helfen, diese Nachricht weiterzuverbreiten?

05.01.2026 13:28 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Are you interested in a postdoctoral position? Do you have experience in mitochondrial biology and in vivo research? Please send me your CV!

05.01.2026 13:25 πŸ‘ 4 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
Four rounded blue icons representing the European Commission’s New Year’s goals: renewable energy and climate protection, affordable housing and access to homes, European security and defence with EU stars shield, and quality jobs and education with a school building, briefcase and graduation cap. The text β€œOur New Year’s Goals” appears below, with the European Commission logo in the bottom right corner.

Four rounded blue icons representing the European Commission’s New Year’s goals: renewable energy and climate protection, affordable housing and access to homes, European security and defence with EU stars shield, and quality jobs and education with a school building, briefcase and graduation cap. The text β€œOur New Year’s Goals” appears below, with the European Commission logo in the bottom right corner.

New Year, new EU goals 🌍

Here are some of our top priorities for 2026 ⬇️

02.01.2026 09:01 πŸ‘ 114 πŸ” 25 πŸ’¬ 7 πŸ“Œ 2
Grafik mit Weihnachtsmotiven und der Heine Statue. Mittig unten steht: Frohe Weihnachten!

Grafik mit Weihnachtsmotiven und der Heine Statue. Mittig unten steht: Frohe Weihnachten!

πŸŽ„ Wir wΓΌnschen allen, die feiern, frohe und besinnliche Weihnachtstage und schΓΆne Momente im Kreise eurer Liebsten!

24.12.2025 09:32 πŸ‘ 13 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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MISO regulates mitochondrial dynamics and mtDNA homeostasis by establishing membrane subdomains - Nature Cell Biology Zhang et al. characterize the mitochondrial inner membrane subdomain organizer (MISO) protein, which responds to inner mitochondrial membrane stress by inducing membrane subdomains promoting homeostat...

MISO: An MTFP1 interactor that regulates inner mitochondrial membrane fusion and quality control

MISO regulates mitochondrial dynamics and mtDNA homeostasis by establishing membrane subdomains | Nature Cell Biology

16.12.2025 15:19 πŸ‘ 16 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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We are hiring!. If you hold a PhD in natural science and are passionate about mitochondria, reach out!

12.12.2025 12:38 πŸ‘ 6 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Congratulations to the new cohort of 28 EMBO Young Investigators! They are joining an international network of more than 800 life scientists – Welcome!

Read the press release here:
https://www.embo.org/press-releases/twenty-eight-group-leaders-become-embo-young-investigators/

02.12.2025 13:06 πŸ‘ 140 πŸ” 32 πŸ’¬ 5 πŸ“Œ 31
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Im neuen BIOspektrum: Spannendes zur QualitΓ€tskontrolle der Mitochondrien:
www.biospektrum.de/system/files...

@dplamartin.bsky.social

24.11.2025 09:27 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Thanks Michele

23.11.2025 09:06 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Mitochondria quality control: preserving the cells’ command center

link.springer.com/epdf/10.1007...

22.11.2025 12:27 πŸ‘ 10 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
Junge Nilgans steht im Halbdunklen an "Uni Mitte".

Junge Nilgans steht im Halbdunklen an "Uni Mitte".

πŸ¦† Junge Stud-Ente genießt das Nachtleben auf dem Campus.
Danke @mel_nrv fΓΌr das Foto! πŸ₯°
^lm

10.11.2025 16:13 πŸ‘ 36 πŸ” 4 πŸ’¬ 4 πŸ“Œ 1
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🌟 Exciting news! Dr. David Pla Martin is joining our Cell & Molecular Biology section as an editorial board member. @dplamartin.bsky.social's work in mitochondrial function, mtDNA, mitochondrial quality, and selective mitophagy will be a fantastic addition. Welcome! πŸ§¬πŸ”‹πŸ§«

23.10.2025 21:20 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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New paper - MAPL strikes again! Interested in mitochondrial signalling, inflammation, lysosome biology, pyroptosis, and Parkinson's disease? Have a look, there's something for everyone! Feeling grateful! @mitocollier.bsky.social Funded by #CIHR, @asapresearch.parkinsonsroadmap.org.
rdcu.be/eKKz1 πŸ‡¨πŸ‡¦

14.10.2025 11:50 πŸ‘ 67 πŸ” 22 πŸ’¬ 4 πŸ“Œ 3
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Protein complex, the retromer, promotes recycling/disposal of damaged mitochondrial DNA

πŸ“· Parisa Kakanj & Mari Bonse et al
@dplamartin.bsky.social
lab University of Cologne, Cologne, Germany in
@science.org Science Advances

➑️ bpod.org.uk/archive/2025... with
@rooph.bsky.social

08.05.2025 10:57 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Cecad is always at the edge of innovation.

29.04.2025 13:57 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Small molecules restore mutant mitochondrial DNA polymerase activity - Nature An activator of DNA polymerase Ξ³ restores function to disease-causing mutant variants and demonstrates a potential route to treatments for inherited mitochondrial disorders involving POLG mutations.

Small molecules restore mutant mitochondrial DNA polymerase activity
www.nature.com/articles/s41...

09.04.2025 16:51 πŸ‘ 18 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0

Thanks Alessandro!

05.04.2025 08:15 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thanks Christian!

05.04.2025 08:15 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thanks Sofia!

05.04.2025 07:18 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

What a lovely paper from @dplamartin.bsky.social and his team! Mechanistic insight to mtDNA turnover at the lysosomes. πŸ“¬

05.04.2025 07:16 πŸ‘ 2 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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Medicine: Publication in Science Advances Damage to the mitochondria, the β€œpower plants” of the cells, contributes to many diseases. Researchers from Heinrich Heine University DΓΌsseldorf (HHU) and the University of Cologne led by HHU professo...

www.hhu.de/en/news-arti... @hhu.de

05.04.2025 04:20 πŸ‘ 8 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

WTH… is VPS35 the next candidate to fight mitochondrial dysfunction? I just leave it here…

04.04.2025 18:42 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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We then used Drosophila and expressed VPS35…. πŸ’₯ πŸ’₯ 🀯

04.04.2025 18:42 πŸ‘ 3 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

Ok! But let’s be serious… we noticed that overexpression of the Retromer increased mtDNA release… could we use this to clean up mtDNA damage?

04.04.2025 18:42 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Not only that! Whenever mtDNA is released, look who’s there?! A lysosome

04.04.2025 18:42 πŸ‘ 2 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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What then? We found that the leak gets inhibited upon inhibition of BAX1 but not VDAC1

04.04.2025 18:42 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0