Philip Bender

Threads thread: thriller_instinct 3d Is it okay to bully 40 and 50 year olds who are on social media just for being on it, cuz like why are you here - 254 Q 3.1K G 28 746 corporateash 18h ••• My ICQ UIN is 7231680. That number is burned into my consciousness. I inadvertently learned that you could see private conversations in public chat rooms when using Telnet instead of a browser on GeoCities. I can tell you the difference in audible dial-up handshakes between 1200, 2400, 14.4 kbps modems. I needed a edu email address to join Facebook after my university was admitted. We were here at the beginning. We made social media. You wouldn't be in my Top 8. I have usernames older than you. 852 Q62 G6 72

“I have usernames older than you.”.
Holy shit

I stopped Target, never eaten Chick-fil-A, don't go to Starbucks, won't go in a Hobby Lobby.

If this feels like virtue signaling, it is.

If you think I'm saying my virtues are somehow better than yours, yes, I'm also saying that.

Stand up for people, not money.

Eat the rich.

The molecular basis of force selectivity by PIEZO2 Nature - PIEZO2 is intrinsically more rigid than PIEZO1, and disparate mechanical stimuli paradoxically evoke opposite conformational and gating responses in each channel.

New paper from the lab led by @ericmulhall.bsky.social addresses how PIEZO1 and PIEZO2 are tuned to different types mechanical forces. From nanometer-scale super-resolution microscopy to in vivo experiments, links single-molecule observations to physiological function.
www.nature.com/articles/s41...

Prairieland ICE shooting trial jury gets closer look at 'antifa' materials defendants owned Anti-fascism, anarchy and the abolition of ICE were common themes in literature and paraphernalia investigators found in the defendants' homes and cars.

“Zines are really like this little atomic unit of freedom of the press with simple pamphlets that you just pass around. It begs the question of whether the prosecution believes that we should have a First Amendment in the first place” #ZinesAreNotACrime
—Lydia Koza, wife of defendant Autumn Hill

Guest post: The CDC hepatitis B study is unethical and must never be published Manjurul/iStock The Committee on Publication Ethics (COPE), an international organization that establishes best practices for scholarly journals, has endorsed specific ethical standards for studies…

"This is not a matter of censorship or 'cancellation' of results that do not square with biases," write Arthur Caplan and Jonathan Moreno. "It is a question of ensuring that there are no incentives for unethical research."

You'd think so, but she has a heat pad and still picks the radiator! 🤷‍♂️

Life is hard, so here is my sweet best friend sleeping on the radiator in her tiny Paris apartment

Screenshot of panel "B" from a scientific paper, showing grey rectangular panels in two rows, three columns, with purple blueish cells in random patterns

Can you spot the overlapping panels? Tell me which ones! The first three correct answers (either by illustration or a good description) will win that shiny Emoji Award.
It will look so good on your resume!
#ImageForensics

Place cells in CA1 lack topographical organization of firing locations | PNAS Topography is a well-described and well-known concept for cortical organization in primary sensory and motor cortices of mammalian brains. Similar ...

A half-century old question may have its final answer. Using high-resolution #Mini2P microscopes, we find no evidence of local topography in #PlaceCells. Place fields of neighbouring cells are no more similar than those of randomly selected cells. 🧠🗺️ Out now in @pnas.org www.pnas.org/doi/10.1073/...

This is totally non-standard for any publication. Every pub everywhere pretty much cleans up uhms, uhm, and vocal tics like that, which EVERYONE DOES.

This is extremely intentional.

If I was writing this I’d probably do the quote “this is of course a very longstanding policy of the United States”

A line graph shown the number of NIH projects funded for fiscal year 2026 (through 2/13/26) compared with fiscal years 2021-2025. The fiscal year 2026 is lagging behind following a slow start due to a government shutdown during October and November.

My weekly NIH update (grants funded through 2/13/26)

All projects...

1/4

Oh the weird old SciTwitter days 😆

Do I correctly remember a "I make my lab members bring me water" conversation too?

📣 The February newsletter of the #ParisPostdocsSeminars is out! Don't miss the exciting talks happening next week at @ibensens.bsky.social, #UFR-Sciences, and @institutcochin.bsky.social

And save the dates 📆 for the ones taking place in the second half of the month!

#seminar #networking #Paris

Do I by chance have any super cool science friends with experience writing a Curie (MSCA) fellowship app who would be willing to share insights and/or materials?

I'll share more once it's all said and done, but I'm just excited to see it progressing!

And not have to think about it from a different continent 🤣

That's the consensus I've been seeing, but I still like to check in. Just to see.

Oooh my first author paper from my short postdoc was just "accepted in principle" so that's cool!

Whenever a new person learns I'm American they look at me like I just told them I am dying.

It's going! Slow start but it's getting there

Rough watching things going on over there

Hey USA friends, how are you all holding up?

Come visit! I'll get you pastries!

Okay but being in Paris helps a little 😋

Research Spotlight 💡
Wu et al. (*Science*, 2025) report the first human microglia replacement therapy. Bone marrow transplantation replaced defective #microglia in ALSP patients, halting disease progression and improving neurological function.
https://www.science.org/doi/10.1126/science.adr1015

I am looking for examples of a 2-3 hour lab activity for a course that would allow college students to get some experience connected to environmental DNA studies (e.g., e-DNA, rRNA/ITS PCR, metagenomics, etc). Ideally this would have some DNA extraction and some follow up processing / analysis.

Notes on winter When the world turns whimsical

Wild fact from @billmckibben.bsky.social's latest newsletter:

"The last colder-than-average month on planet earth was in February of 1985, which means that no one under the age of forty has ever known one."

PLEASE REPOST AND SHARE!

My intro biology course has an "Interview a Biologist" project where students connect with a wide range of biologists using cell/molecular tools.

If you are willing to speak with a student for ~30 minutes on Zoom, please fill out this form: forms.gle/BCjJPgURsgSr...

I wishhhhj

“I’m mad I can’t understand Bad Bunny’s lyrics because they’re not in English”

my brother millions of metalheads around the world have been happily listening to incomprehensible Finnish shrieks and Japanese death grunts since we were teens, you’re just boring and racist

First pass for imaging experiments on a new rig tomorrow!

I'm sure there will be troubleshooting but right now just excited to get back into it!