🧬🔬🎥 @science.org Live-cell single-molecule dynamics of eukaryotic RNA polymerase machineries | Science www.science.org/doi/10.1126/...
06.02.2026 00:14
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🧬🔬🎥 @science.org Live-cell single-molecule dynamics of eukaryotic RNA polymerase machineries | Science www.science.org/doi/10.1126/...
FYI, Eira Bio is #hiring for a Senior Research Associate/Associate Scientist in Protein Science. This is a unique opportunity to join an exceptional team developing transformative therapies that are rapidly progressing toward the clinic.
www.eirabio.com/home#careers
Our company has a new name, Eira Bio (www.eirabio.com) (formerly K2 Therapeutics), but the same important mission to apply our advanced synthetic biology, directed evolution, and protein design technologies to discover and develop next-generation antibody-based medicines for a range of diseases!
This is a beautiful paper examining the molecular genetics of facultative multicellularity in a marine black yeast.
I also love that they figure out the ecological context for the behavior (MC form when in sponges, where there are nutrients, & uni when starving!).
www.nature.com/articles/s41...
Took us a bit, but proud of this published version. We now examine the genetic interaction of phosphorylation with oligomerization and where bulk and phospho-Swi6 localize. Wonder if chromatin affinity tuning to enable Suv39 H3K9me3 spreading is a conserved mechanism ?
doi.org/10.1093/nar/...
🚨 AIMBE calls on the scientific community to urge Congress to ensure timely passage of the FY2026 budget 👇
Strong, sustained funding for our nation's health and science agencies is essential for economic prosperity, U.S. global competitiveness, and public heath.
takeaction.io/aimbe/protec...
JOB OPPORTUNITIES!!
FYI, K2 is #hiring for two positions in the Research Biology and Synthetic Biology teams! If you’re excited about using cutting-edge science to solve big problems, then check out our careers page (lnkd.in/gvtFnZ5K) and apply now.
Years ago, we set out to develop new synbio technology to solve a major drug discovery challenge: generating precision antibodies for challenging membrane proteins.
It's a DREAM COME TRUE to report that we've launched K2 Therapeutics (k2-tx.com) to advance this into transformative medicines!
Congratulations on this exciting next step, Rita!
In today's issue of Cell-->if you are looking for a good distraction from the news (who isn't), check it out!
www.cell.com/cell/fulltex...
We traveled to DC to talk to Congressional Staffers about the impact of NIH and NIBIB funding. It enables us to develop synthetic biology tools to advance cell & genetic medicines for patients in need. REPOST to deliver the message that SCIENCE saves lives & makes America GREAT!
7 years old! 🎂🎉🎈Happy birthday to our adventurous twins!
I hailed a Tesla Model 3, according to Uber-equivalent in Cairo, Egypt 😂😂
Excited to share that our work building in vivo biosensors for receptor tyrosine kinases (pYtags!) is now out www.cell.com/cell-reports...
9/n Rabat
8/n Fes
7/n MORE Mergouza desert camp
6/n Mergouza desert camp
5/n Toudgha Gorge
4/n Kasbah Ait Ben Haddou
3/n Driving through the High Atlas Mountains
2/n Marrakech
1/n Morocco 🇲🇦 is magical. A few pics from our whirlwind tour through this beautiful country. Enjoy!
So cool, a novel archaeon with a super small genome and no metabolic genes!
"An unprecedented level of metabolic dependence on a host, a condition that challenges the functional distinctions between minimal cellular life and viruses."
www.biorxiv.org/content/10.1...
Excited to share that our study, on how T cells selectively sense foreign antigens with single-molecule sensitivity, is out! This work was led by the brilliant Will White, and done in collaboration with Jay Groves and David Baker @uwproteindesign.bsky.social
www.pnas.org/doi/10.1073/...
Furiously logging all the new budget news, laughing grimly that it landed *just after* we hit publish. Of course it did.
Grateful that the entire point of @unbreaking.org is to give us a durable platform where we can keep integrating new developments. We'll digest, contextualize & update next week.
I urge everyone to read Unbreaking’s new page on everything the govt is doing to destroy & diminish medical research funding.
It’s the best thing I’ve read on this topic: @lizneeley.bsky.social & co have such done an incredible job.
unbreaking.org/issues/medic...
Happy to share the peer-reviewed and updated version of our work on OrthoRep-driven evolution of aaRSs for genetic code expansion with unnatural amino acids. Congrats to Yuichi Furuhata, a true master bioengineer, on leading this excellent work! www.nature.com/articles/s41...
🧬🧫🦠 @science.org Bacterial reverse transcriptase synthesizes long poly-A–rich cDNA for antiphage defense | Science www.science.org/doi/10.1126/... #microbiology #bacteriophage #antiphage #immunity #DNA #RNAsky #RT #Cryo-EM #DRT9
