The @steinaerts.bsky.social lab is looking for a postdoctoral researcher to develop next-generation sequence-to-function models for glioblastoma, one of the most aggressive brain cancers.
More info & how to apply π https://vib.ai/en/opportunities#/job-description/130090
13.02.2026 10:02
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Highlighting two manuscript additions:
1. Data ablation (Supp. Fig 12): RNA-seq + ATAC/DNase proved essential for key evals. h/t @anshulkundaje.bsky.social for the suggestion!
2. Variant Analysis: We found evidence to upgrade a 3β UTR VUS from Ellingford et al 2022 to "likely pathogenic."
28.01.2026 21:02
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AlphaGenome is out in @nature.com today along with model weights! π§¬
π Paper: www.nature.com/articles/s41...
π» Weights: github.com/google-deepm...
Getting here wasnβt a straight path. We discussed the story behind the model, paper & API in the following roundtable: youtu.be/V8lhUqKqzUc
28.01.2026 21:02
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Please consider attending and RT. Great lineup of speakers!
18.12.2025 21:20
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AITHYRA Global Adjunct Principal Investigator Program:
Advancing AI-Driven Life Science Through Global Collaborations
Learn more about the Program: aithyra.at/fileadmin/do...
Application Deadline, 30 January 2026: application@aithyra.at
#AITHYRA #GlobalAdjunctPI
15.12.2025 15:12
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Programmatic design and editing of cis-regulatory elements
The development of modern genome editing and DNA synthesis has enabled researchers to edit DNA sequences with high precision but has left unsolved the problem of designing these edits. We introduce Le...
After a huge amount of work w/ @alex-stark.bsky.social's group, a new version of our Ledidi preprint is now out!
In an era of AI-designed proteins, the next leap will be controlling when, where, and how much of these proteins are expressed in living cells.
www.biorxiv.org/content/10.1...
10.12.2025 15:18
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Excited to share Nona: a unifying multimodal masking framework for functional genomics.
Models for DNA have evolved along separate paths: sequence-to-function (AlphaGenome), language models (Evo2), and generative models (DDSM).
Can these be unified under a single paradigm? 1/15
10.11.2025 21:01
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AITHYRA Starting PIs Ariane Mora, Jason Nomburg, Alex Tong, Xinyi Zhang offer several postdoc positions in Vienna.
The Starting Principal Investigators at #AITHYRA the Research Institute for Biomedical Artificial Intelligence of the OeAW in Vienna invite outstanding candidates to apply for postdoctoral positions in the field of AI/ML & Life Sciences.
www.oeaw.ac.at/aithyra/post...
Please apply by 20 Nov 2025!
20.10.2025 12:40
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π¨ Exciting opportunity! The Eric and Wendy Schmidt Center at the Broad Institute of MIT and Harvard is recruiting exceptional postdocs for 2026 at the intersection of ML/math and biomedicine.
Shape the future of computational biology π§΅π
22.10.2025 02:50
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My team has a postdoc position available now, join us!
careers.gene.com/us/en/job/20...
19.09.2025 20:12
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We have a postdoc position in my team. Join us if you are passionate about genomics, human genetics, synthetic biology and agentic AI!
careers.gene.com/us/en/job/20...
12.10.2025 05:20
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Iβll be in Boston for #ASHG25 next week and am looking forward to meeting everyone! Please ping me if you want to catch up, or catch me after my talk on Thursday morning (Itβs the first thing on Thursday morning. Iβm sure you all will be awake)
08.10.2025 00:48
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Now that I'm settled in at @umasschan.bsky.social, I'm hiring at all levels: grad students, post-docs, and software engineers/bioinformaticians!
The goal of my lab is to understand the regulatory role of every nucleotide in our genomes and how this changes across every cell in our bodies.
07.10.2025 15:24
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Open rank tenure-track position in comp bio at the University of Montreal. Great environment, great position. @futurepislack.bsky.social
medecine.umontreal.ca/wp-content/u...
03.10.2025 21:24
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Group Leader β AI in Biology
Are you ready to lead groundbreaking research in AI for Biology? Join us at EMBL! We are seeking a visionary scientist to establish their own independent research group bridging innovations in machine...
Are you an AI expert who wants to stay in academia and change the world by understanding the most complex things we know - living organisms? Want to lead your own group, based in Heidelberg DE, working language English? @embl.org is hiring in AI embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
08.09.2025 11:43
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We have an exciting new opportunity for a postdoc in our team at Genentech! Please share.
19.09.2025 21:20
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scVerse conference is at Stanford this year! Encourage folks (especially Bay Area/West coast folks) to sign up and attend. Cool workshops/talks and other events + great community of developers for one of the most widely used open source software for single cell data analysis!
26.08.2025 18:50
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Stealth genomics startup focused on non-cancer diagnostic applications
Senior Deep Learning Engineer
β’ Ph.D. in relevant field with 3+ years practical experience in deep learning for biology
β’ Demonstrated proficiency in building DL architectures using Pytorch or TensorFlow+Keras.
β’ Substantial expertise in training lightweight deep learning models and tuning large foundation models.
β’ Substantial expertise with developing efficient data loaders for large datasets and optimizing training workflows.
β’ Deep expertise training and deploying models in Cloud-based compute environments and local hardware.
β’ Sufficient knowledge of the genomics of gene regulation to ask the right questions for the specific information to be gained.
β’ Expertise in developing models of gene regulation and sequence-to-function models is a plus.
β’ Interactive team player in highly collaborative small setting. Experience collaborating and communicating with biologists.
Interested candidates can send their CV to anshul @ kundaje . net
Job Alert: A stealth startup focused on non-cancer diagnostics is keen to hire a deep learning for genomics/bio engineer. I am an advisor for the startup & closely involved. Please see the job description below and get in touch if interested. Plz forward.
12.08.2025 00:35
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Looking forward to seeing how you decorate that empty space!
20.08.2025 20:52
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@jengreitz.bsky.social l & my lab want to co-hire a computational biologist/biostatistician with project management expertise to help map the regulatory code of the human genome and discover genetic mechanisms of disease.
Details below
careersearch.stanford.edu/jobs/computa...
Plz RT
19.08.2025 00:29
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Join us for our next Kipoi Seminar with Katherine Pollard, Gladstone Institute of Data Science & Biotechnology,UCSF, Biohub
@gladstoneinst.bsky.social @czbiohub.bsky.social
πHuman variant interpretation with sequence-to-activity models
π
Wed June 4,5:30pm CET𧬠kipoi.org/seminar/π¦@kipoizoo.bsky.social
28.05.2025 13:06
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Computational Biologist (Single-cell Genomics / ML) β Single-cell Analytics Innovation LabChaligne Lab Website
The Single-cell Analytics Innovation Lab
@mskcancercenter.bsky.social is expanding and looking for ML-oriented computational biologists. Join our team based in NYC to work on cutting-edge single-cell & spatial transcriptomics methods in collaboration with leading research labs. bit.ly/4lTEr2t
26.05.2025 15:13
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The premier conference on Machine Learning for Computational Biology is Sep 9-10 at the NY Genome Center in NYC!
Submission deadline is June 1 for 2-page abstracts and 8-page papers (eligible for proceedings track).
Registration is now open! (Link below)
Please retweet!
16.05.2025 11:26
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Polygraph: a software framework for the systematic assessment of synthetic regulatory DNA elements - Genome Biology
The design of regulatory elements is pivotal in gene and cell therapy, where DNA sequences are engineered to drive elevated and cell-type specific expression. However, the systematic assessment of synthetic DNA sequences without robust metrics and easy-to-use software remains challenging. Here, we introduce Polygraph, a Python framework that evaluates synthetic DNA elements, based on features like diversity, motif and k-mer composition, similarity to endogenous sequences, and screening with predictive and foundational models. Polygraph is the first instrument for assessing synthetic regulatory sequences, enabling faster progress in therapeutic interventions and improving our understanding of gene regulatory mechanisms.
Polygraph - a python package to characterize synthetic cis-regulatory elements - is published! Polygraph reveals regulatory mechanisms exploited by design methods, diagnoses out-of-distribution issues, and helps generate more realistic synthetic DNA. genomebiology.biomedcentral.com/articles/10....
09.05.2025 19:45
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