Magda del Río

Now out! 👉 rdcu.be/eZ27x

It's #MentalHealthAwareness week - time for facts: OCD is not about being tidy. It’s a serious mental health condition rooted in brain processes — and we’re studying it.
Learn more on OCD & the Brain:
ocdandthebrain.com
@ocdaction.bsky.social @tueneurocampus.bsky.social @uclbrainscience.bsky.social

Can't believe this was 10 years in the making! 🤯

Our work highlights altered information integration as a potential driver of indecisiveness. Huge thanks to everyone involved in the project: Nadescha Trudel, Gita Prabhu, @lhuntneuro.bsky.social, Michael Moutoussis, & Ray Dolan! 🎉

Using MEG 🧠, we can decode updates in evidence strength from wholebrain activity as a late component, decodability peaking around 920 ms. Mirroring the behavioural findings, high-OC participants show reduced decodability in these updates, particularly in mediofrontal regions.

In the behavioural data, we find that when we’re deciding to decide, we overweight the most recent information - we’re calling this update in evidence strength ΔES. These updates tend to nudge us to commit to a decision, but the effect is reduced along the OC spectrum across both samples.

We’re looking at information gathering using behaviour and #MEG in a big online sample (N>5000) and a lab-based sample (N>100) including #OCD and #GAD patients taking a dimensional transdiagnostic approach.

Indecision and recency-weighted evidence integration in non-clinical and clinical settings Biases in information gathering are common in the general population and can reach pathological extremes in paralysing indecisiveness, as in obsessive-compulsive disorder (OCD). Here, we adopt a new p...

New preprint from my postdoc with @tobiasuhauser.bsky.social at the MPC!

TL;DR: there is a strong recency bias in information gathering and it is attenuated in people on the #OCD spectrum - a possible mechanism for #indecisiveness 🤔

Paper here: www.biorxiv.org/content/10.1...

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