Madeline Andrews

The Pearson lab is looking for an enthusiastic research technician to join our team! Come join us in New York City! 🍎🧪
jobs.weill.cornell.edu/NY/job/New-Y...

#science #neurobiology #devbio

That's a wrap on #sfn 2025! First big conference as a lab - was wonderful to see old friends, share our work, and hear great science

🚨 Calling all postdocs 🚨

We are soliciting applications to our 8th cohort of Fred Hutch Dr. Eddie Méndez Scholars! Awardees will be invited to present at a symposium celebrating their achievements 🧵

Apply here 👇 👇 👇
apply.interfolio.com/176955
📆 Applications due 2/1/2026

First-ever atlas of brain development shows how stem cells turn into neurons
There are 6 excellent human brain development papers in Nature - www.nature.com/articles/d41... Check them out!

Candid photo of Zara Weinberg. She has short red hair, bangs and glasses. She is laughing.

The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor.

The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.

www.leadingedgesymposium.org/apply/

🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x

Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signaling @cellcellpress.bsky.social @travisfaust.bsky.social
www.cell.com/cell/fulltex...

My book, An Intuitive Primer on Effective Functional Genomics Study Design, is published! I’d really appreciate it if you could help spread the word, and I’d love to hear your thoughts and feedback. I hope people will find it useful.

It’s available on Amazon: tinyurl.com/mx2hewen

Sex differences in the developing human cortex intersect with genetic risk of neurodevelopmental disorders Autism is highly heritable and diagnosed more frequently in males than females. To identify neurodevelopmental processes that might present sex-biased vulnerability, we generated transcriptomic and ep...

New preprint by @labnowakowski.bsky.social
& colleagues: Sex differences in the developing human cortex intersect with genetic risk of neurodevelopmental disorders, identifying “two points of vulnerability contributing to the sex-biased penetrance in neurodevelopmental disorders” 🧪🧠🧬

Species-specific Rates of Fatty Acid Metabolism Set the Scale of Temporal Patterning of Corticogenesis through Protein Acetylation Dynamics Developmental processes display temporal differences across species, leading to divergence in organ size and composition. In the cerebral cortex, neurons of diverse identities are generated sequential...

New from the lab: Fatty Acid Metabolism Sets the Species-specific Tempo of Cortical Development through Protein Acetylation Dynamics. Led by amazing trio: @ryo2iwata.bsky.social , Isabel Gallego, @emirerkol.bsky.social, together with @steinaerts.bsky.social , @fendtlab.bsky.social

Calling all Neuroscience postdocs! 🧠 Share your research through SPiNES (Seminars from Postdocs in Neuroscience: Extramural Series) from the NYUGSoM Department of Neuroscience. Applications close 08/20/25. Apply today! 👉 nyumc.qualtrics.com/jfe/form/SV_...
#Neuroscience #Postdoc #ResearchOpportunity

A The major components of the CSF system include CSF, choroid plexus, and circumventricular organs. These systems change their properties across time of day, including those listed below each component. B Multiple inputs affect the CSF system across time of day.

How does the brain 🧠 change around the clock 🕰️? Can this inform treatments?

Learn more in a new review from the lab 'Harnessing the #circadian nature of the choroid plexus and cerebrospinal fluid' ➡️ npj Biological Timing & Sleep | #Nature @natureportfolio.nature.com
www.nature.com/articles/s44...

A human-specific enhancer fine-tunes radial glia potency and corticogenesis - Nature HARE5, a human accelerated region enhancer, modulates cortical development by influencing neural progenitor cell behaviour, leading to an enlarged neocortex with increased functional independence betw...

Thrilled to share our latest study out in @natureportfolio.nature.com led by the fantastically talented Jing Liu. Our study provides insight into a long standing question in biology: What molecular features make us uniquely human and how do these function? www.nature.com/articles/s41...

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations!

These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.

Save and share the post!

Introducing CellBouncer, a unified demultiplexing toolkit built by nkschaefer.bsky.social to check IDs and keep the riff raff out of single cell genomics datasets, including by using genetic variation as an external ground-truth for ambient RNA removal:

www.biorxiv.org/content/10.1...

Genetic variation modulates susceptibility to aberrant DNA hypomethylation and imprint deregulation in naive pluripotent stem cells Pluripotent stem cells are susceptible to acquiring detrimental epigenetic abnormalities, posing a hurdle to their safe use in biomedical applications. Using pluripotent cells with defined genetic backgrounds, Stadtfeld and colleagues show that genetic variation is a major driver of epigenome stability and identify candidate regulators. These findings will enable novel approaches to stabilize the epigenome of pluripotent cells in culture.

Our collaborative project with Matthias Stadtfeld and Jason Mezey labs has now been published. We examined how genetic variation impacts regulation of DNA methylation at the control regions of imprinted genes in naive pluripotent stem cells.

www.cell.com/stem-cell-re...

Exciting new study from @bhadurilab.bsky.social on metabolic regulation of human cortical development!

Happy International Women's Day!
Science is a team sport and I'm so thankful to be part of such a strong squad of #womeninSTEM
@suprajagv.bsky.social @madelineandrews.bsky.social @jennkong.bsky.social @katrinaladams.bsky.social 🧪💪👩‍🔬🦄

About our grants Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings,…

The deadline for the following grants is 7 March:
- Scientific Meeting Grants
- Grants from our Fund for Innovations in Sustainable Conferencing
- JCS-FocalPlane Training Grants @jcellsci.bsky.social @focalplane.bsky.social

Find out more and apply at: www.biologists.com/grants

Scientists Secure $10.3 Million CIRM Grant to Advance Stem-Cell Therapies for Neuropsychiatric Disorders A team of researchers from the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF and UCLA, along with the UC Santa Cruz Genomics Institute, has been awarded a $10.3 m...

Grateful for this funding and the opportunity to work with a phenomenal group of scientists to study a novel hypothesis with patient impact. 🧫🔬🥼👶🏻👧🏾👦🏽 @bhadurilab.bsky.social @zeigerlab.bsky.social
stemcell.ucsf.edu/news/scienti...

🚨Job Alert @arcadiascience.com!

Are you an independent, generative, rigorous scientist that can pivot quickly? Can you apply your unique skills to a wide range of bio & tech problems? Can you work with other stellar scientists skilled in orthogonal domains? Join us!

jobs.lever.co/arcadiascien...

Spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis - Nature Genetics Xenium spatial transcriptomic profiling of pulmonary fibrosis characterizes cell composition dynamics and histopathological features associated with the disease.

Excited to post my first #skySplain about our recent work published yesterday in Nature Genetics! www.nature.com/articles/s41.... One of the first authors of this study - Annika Vannan – actually wrote this breakdown, but she's not yet over here on bluesky and asked me to post!

Multi-modal investigation reveals pathogenic features of diverse DDX3X missense mutations Author summary DDX3X mutations are associated with neurodevelopmental disorders, including DDX3X syndrome and autism spectrum disorder. DDX3X is an RNA binding protein whose loss of function impairs b...

Happy to share some good news today, and our latest study on DDX3X! Led by super talented @federicamosti.bsky.social we use live imaging, transcriptomics and interaction studies to define how clinically diverse missense mutations in DDX3X influence neural development. dx.plos.org/10.1371/jour...

L'Oréal USA For Women in Science The L’Oréal USA For Women in Science program has awarded 80 postdoctoral women scientists over $4 million in grants since 2003.

The L’Oréal USA For Women in Science program awards women postdoctoral scientists. Candidates must have their PhD, started their postdoctoral research position, and be a U.S. citizen or permanent resident. Applications due 5:00pm ET on Friday, February 14.

www.loreal.com/en/usa/pages...

We enjoyed discussing two interesting new preprints that evaluate instructive roles of metabolism in neurodevelopment. Thanks for the invitation @dev-journal.bsky.social!

WEBseq share freely

Hi #neuroscience community! This is one of my favorite posts ever. In close collaboration with @liddelowsa.bsky.social and Ye Zhang, we've built a new tool that we are eager to share! www.webseq.net

We are now accepting applications for speakers from Native American trainees - if you know of someone who would be a good fit, encourage them to apply! More info in the original thread

Apply to be speaker at Full Circle here: forms.gle/dMUtGWvigrNA...
PS: We have travel funds available!
Plz share!

Generation and long-term culture of human cerebellar organoids from pluripotent stem cells Nature Protocols - Generation and long-term culture of a human pluripotent stem cell-derived human cerebellar organoid model, which successfully replicates the cellular diversity of the fetal...

We're excited to share our comprehensive protocol for generating human cerebellar #organoids, addressing the many requests we've received from the scientific community! Congratulations to Alex Atamian, @marcellabirtele.bsky.social, and Negar Hosseini! rdcu.be/d13Zu @natureportfolio.bsky.social

We are happy to report that our journals and community sites now have Bluesky accounts. Follow them at:
@dev-journal.bsky.social
@jcellsci.bsky.social
@jexpbiol.bsky.social
@dmmjournal.bsky.social
@biologyopen.bsky.social
@the-node.bsky.social
@prelights.bsky.social
@focalplane.bsky.social

Macy’s Day Parade Turkey float going down Central Park West on Thanksgiving day

Do you want to experience Thanksgiving in New York? The Pearson lab is hiring! Research technician and post doc position available