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Kevin Downes

@kevinjdownes

Peds ID doc and clinical pharmacologist at CHOP. #TransplantID #DoseMatters

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Latest posts by Kevin Downes @kevinjdownes

I’m coming for you…

03.01.2026 18:40 👍 1 🔁 0 💬 1 📌 0

With all the things going on in the world of pediatric ID, misuse of the abbreviation CTX for ceftriaxone might be the most consequential. Please raise awareness. The wellness of many a Peds ID specialist is at stake.

03.01.2026 14:14 👍 4 🔁 0 💬 1 📌 0

Does Amazon Prime target tv ads to you? Because if so, I have a lot of diseases that are only treatable with biologics.

27.07.2025 03:54 👍 2 🔁 0 💬 0 📌 0

Based on the television shows I’ve been watching, I do not drink enough bourbon.

26.07.2025 20:51 👍 1 🔁 0 💬 0 📌 0

What about non-dangerous GOF research. Is that okay? Feels like there’s wiggle room here…

25.05.2025 19:07 👍 0 🔁 0 💬 0 📌 0

Because of “national security.” 🙄 How do we make Americans safer by stifling international collaborations?

03.05.2025 19:51 👍 1 🔁 0 💬 0 📌 0

Please to be Co-Chair & Faculty at the #2025ACCP Annual Meeting, Sept 14-16. My presentation Pediatric Clinical Trial Applications: Challenges & Opportunities will be part of Symposium 11: Thinking Big by Going Small: Applications of Microsampling in MIPD & PK Modeling on 9/16. Join us!

18.04.2025 16:47 👍 1 🔁 0 💬 0 📌 0

I feel like we should all come up with the most ludicrous thing imaginable to cut and see who wins. I mean we’d all lose, but one of us would be right at least.

27.03.2025 03:05 👍 2 🔁 0 💬 1 📌 0

So I ask again…

15.03.2025 15:37 👍 0 🔁 0 💬 0 📌 0
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Some creative signs at the Stand Up for Science March in Philly

07.03.2025 18:41 👍 2 🔁 0 💬 0 📌 0
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So proud of my team for marching for science! Wish I could have been there. #SaveScience

07.03.2025 18:32 👍 6 🔁 3 💬 0 📌 0

Unconscionable. America first and only

27.02.2025 12:21 👍 1 🔁 0 💬 0 📌 0

It’s for large cats. Hard to tell from the pictures but there is a panther in there.

27.02.2025 03:28 👍 0 🔁 0 💬 0 📌 0

I personally would like to see a list of 5 fraudulent things that the administration eliminated last week.

27.02.2025 03:26 👍 1 🔁 0 💬 1 📌 0

You can spend $10

Cost | H | N | H | N
———————————
$4 | 1 | 1 | 2 | 2
$3 | 3 | 3 | 4 | 4
$2 | 5 | 5 | 6 | 6
$1 | 7 | 7 | 8 | 8

What you got?

27.02.2025 03:11 👍 1 🔁 0 💬 0 📌 0

And we thought this year was bad…

27.02.2025 00:42 👍 1 🔁 0 💬 0 📌 0

As my fellowship director once said, “The bugs don’t care how the drug gets there.” But you have to get the drug there. Most likely if IV is superior to PO it’s because we used the wrong dose PO.

23.02.2025 19:19 👍 3 🔁 0 💬 1 📌 0

Preventing access to vaccines will achieve the same goal as banning them. And our children will suffer for it.

20.02.2025 22:28 👍 16 🔁 2 💬 0 📌 0

This is truly a shame. These are future leaders of our public health system

15.02.2025 01:49 👍 1 🔁 0 💬 0 📌 0

Right. My immediate answer is, “Ugh…”

15.02.2025 00:32 👍 1 🔁 0 💬 1 📌 0

Does anybody have good news? This is getting out of hand…

14.02.2025 23:58 👍 1 🔁 0 💬 1 📌 0

Do any microbiome researchers know if the terms alpha diversity and beta diversity will get your grant flagged by anti-DEI screening tools? Yes, I’m serious. #NewWorld

12.02.2025 21:56 👍 1 🔁 0 💬 0 📌 1

Thank goodness it’s finally baseball season…

10.02.2025 11:56 👍 0 🔁 0 💬 0 📌 0

Except that the biggest impact these cuts will have is not on patients today, it’s on patients 10 or 20 years from now. The moves that institutions and researchers will have to make to accommodate these changes will fundamentally alter research capacity and quality.

09.02.2025 15:00 👍 1 🔁 0 💬 0 📌 0

More support for Bayesian AUC. At some point we will accept that troughs are just not good enough, right?

09.02.2025 14:43 👍 1 🔁 0 💬 1 📌 0

A valid concern but have to keep moving it all forward. Let’s hope this is just another hurdle.

23.01.2025 02:42 👍 1 🔁 0 💬 0 📌 0

Just so we are clear, renaming a mountain and a body of water were numbers two and three on my list of priorities for this new administration. Sigh of relief for sure.

22.01.2025 04:17 👍 1 🔁 0 💬 0 📌 0

My thoughts exactly

09.01.2025 23:13 👍 3 🔁 0 💬 0 📌 0

If we’re going to rename the Gulf of Mexico, can we rename New England while we’re at it? Rhode Island has gotten away with too much for too long

09.01.2025 04:50 👍 1 🔁 0 💬 0 📌 0

As we head into 2025, I would like to remind those in charge that defunding the NIH will not work out well for anyone, especially our children

01.01.2025 05:53 👍 3 🔁 0 💬 0 📌 0