Andreas MΓΌller's Avatar

Andreas MΓΌller

@andimicroscopy

Scientist at Paul Langerhans Institute Dresden. Interested in the structural features of pancreatic beta cell function and signaling. πŸ”¬

621
Followers
737
Following
27
Posts
13.11.2024
Joined
Posts Following

Latest posts by Andreas MΓΌller @andimicroscopy

Video thumbnail

Excited to share our new paper (CVPR 2026 πŸš€): "MuViT: Multi-Resolution Vision Transformers for Learning Across Scales in Microscopy" which enables local predictions to use global context.
Great work led by @albertdm.bsky.social & another fun collab w @gioelelamanno.bsky.social! @scadsai.bsky.social

02.03.2026 13:42 πŸ‘ 59 πŸ” 25 πŸ’¬ 1 πŸ“Œ 2

We opened 4 PhD positions at @humantechnopole.bsky.social together with Polimi (see πŸ‘‡).

My lab offers a PhD project on "Computational Morphogenesis": use state-of-the-art machine learning methods together with realistic simulations to build digital twins of developing tissue.

Apply by March 26.

05.03.2026 07:46 πŸ‘ 16 πŸ” 9 πŸ’¬ 1 πŸ“Œ 0
PoL – Physics of Life | Team | PoL Groups | Benjamin Friedrich Physics of Life: Discover new paradigms for understanding life and deepen our knowledge of living biological matter

Looking for a theory partner for an #HFSP project? #morphogenesis in cells and tissues, #chemotaxis, #cilia? Feel free to reach out! Deadline for letters of intent 26.03.2026.
physics-of-life.tu-dresden.de/team/pol-gro...

03.03.2026 07:17 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

pH-dependent trapping of cationic amphiphilic drugs perturbs insulin granule homeostasis https://www.biorxiv.org/content/10.64898/2026.02.19.706757v1

20.02.2026 15:30 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Post image

AI based analysis of human pancreatic histology provides a foundation for future research into relevant diagnostic and therapeutic targets, refining several hypotheses regarding tissue alterations associated with #T2D www.nature.com/articles/s41...

10.02.2026 11:19 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

There are just a few days (and spots!) left to apply to this EM course with a focus on marine samples 🌊 do not miss it!

09.02.2026 14:49 πŸ‘ 6 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
Cilia2027, the 7th European Cilia Conference to be held in Italy from March 8th- 12th, 2027.

Cilia2027, the 7th European Cilia Conference to be held in Italy from March 8th- 12th, 2027.

🌍 Cilia2027 | Mar 8–12, 2027 | πŸ“ Stresa, Lake Maggiore, Italy

Join the global cilia community for science, collaboration & discovery (+ fun!!).

#Cilia2027 #CiliaBiology

16.12.2025 15:29 πŸ‘ 14 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0

Villin-SNAP25 interaction regulates insulin secretion downstream of ICA512 signaling https://www.biorxiv.org/content/10.64898/2026.01.13.699220v1

14.01.2026 04:30 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Preview
Imaging spotlight: Revealing mouse brain ultrastructure using non-destructive X-ray tomography - FocalPlane Imaging spotlight: Revealing mouse brain ultrastructure using non-destructive X-ray tomography - News

πŸ”¬πŸ”¦Our latest β€˜Imaging spotlight’, by @carlesbosch.bsky.social, Ana Diaz, @adrianawanner.bsky.social & @andreas-t-schaefer.bsky.social, highlights the non-destructive X-ray tomography pipeline that the authors developed to map mouse brain ultrastructure & considers future applications & developments.

14.01.2026 11:14 πŸ‘ 11 πŸ” 4 πŸ’¬ 0 πŸ“Œ 1

Microscopy Bat signal!

I want to compile a list of biological samples that demonstrate microscope capabilities, including the reagents to generate them. Please send me anything you know of!! Beads are great for QC, but there's a different teaching benefit with biology. 1/n

08.12.2025 14:27 πŸ‘ 17 πŸ” 14 πŸ’¬ 2 πŸ“Œ 0
Video thumbnail

20-plex volumetric super-resolution imaging of cellular ultrastructure. Preprint, led by @seweryn-galecki.bsky.social, dropping soon.

01.01.2026 23:10 πŸ‘ 38 πŸ” 7 πŸ’¬ 2 πŸ“Œ 1

Surprise mother$#@%er!

Q: What does this mean for neural systems to understand them?

A: We absolutely need the wiring diagram. All synapses, chemical and electrical.

#Connectomics

01.01.2026 06:55 πŸ‘ 42 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0

Happy that we could contribute to this amazing study.

13.12.2025 13:07 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

πŸ’₯I am excited to present our first research paper from the lab about caveolae lipid trafficking πŸŽ‰ Led by my fantastic PhD candidate @estherocket.bsky.social

Here we looked into caveolae mediated dietary lipid uptake and how this process is mechanistically facilitated πŸ‘‡ 1/n

11.12.2025 07:08 πŸ‘ 44 πŸ” 17 πŸ’¬ 6 πŸ“Œ 0
Preview
Method of the Year 2025: electron microscopy-based connectomics - Nature Methods A large network of interconnected neurons serves as the basis of brain function and of behavior. Methodological advances have enabled the reconstruction of large-scale and even whole-brain connectomes...

Our Method of the Year 2025 is...drumroll please...EM-based connectomics!!

Our Editorial introduces our choice and highlights six Comments and other related content in this special issue. Please join us in celebrating EM-based connectomics! πŸŽ‰πŸ§ πŸ”¬

www.nature.com/articles/s41...

08.12.2025 16:59 πŸ‘ 52 πŸ” 21 πŸ’¬ 1 πŸ“Œ 2
Wie wird Insulin produziert? 🩸 | Kurze Frage über Diabetesforschung & Betazellen
Wie wird Insulin produziert? 🩸 | Kurze Frage über Diabetesforschung & Betazellen YouTube video by TU Dresden entdecken

The TUD has made a very nice video in their "Kurze Frage" series featuring PLID member Andreas MΓΌller where he explains how insulin is produced by the beta cells of the pancreas and why this is important in diabetes (German only)

#TUDresden #DiabetesResearch #PLID #HelmholztzMunich

03.12.2025 12:24 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Here is a short video by @tudresden.bsky.social (in German) of me explaining what beta cells do and talking about our research on investigating the structural features of their function and dysfunction.

03.12.2025 11:28 πŸ‘ 12 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Interested in applying U-ExM to cells, tissues, organoids, or cryo-sections? Our EMBO workshop is open for applications!
πŸ§«πŸ”¬ Deadline: 12 Jan 2026 β€” don’t miss it!

02.12.2025 15:13 πŸ‘ 17 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0
Preview
Toward better 2D - 3D registration in BigWarp BigWarp has so far focused on 2D-2D or 3D-3D registration, and not on 2D-3D registration. After a conversation with @Christian_Tischer , we thought some simple UI changes could make the support for 2...

Do you have 2D-to-3D image registration challenges? Let me know about them here
forum.image.sc/t/toward-bet...

29.11.2025 18:03 πŸ‘ 20 πŸ” 11 πŸ’¬ 0 πŸ“Œ 0
Video thumbnail

Our new paper showcasing molecular connectomics with pan-expansion microscopy is out in @natbiotech.nature.com! www.nature.com/articles/s41...
This wonderful collaboration with @bewersdorflab.bsky.social was led by Ons M'Saad (now founder/CEO of Panluminate) and @allisonphysics.bsky.social. (1/5)

27.11.2025 04:39 πŸ‘ 61 πŸ” 24 πŸ’¬ 1 πŸ“Œ 0

#Cilia and #Centrosome friends- tomorrow is the big day!! πŸŽ‰ πŸŽ‰

Organoids for #PCD, #CryoET of the base of motile cilia, TZ organization in #IRDs, macrophages & cystic niches in #PKD, how pro-inflammatory lipids & #adipogenesis AND cilia as signal-sending organelles shedding #EVs! 🀩 😍 Join us!!

24.11.2025 11:04 πŸ‘ 13 πŸ” 5 πŸ’¬ 0 πŸ“Œ 1

Scientific journals: we don’t want you using generative AI because it makes shit up.

Same journal: here is an AI summary or evaluation of this paper. This might be more useful than the actual abstract or paper that the authors freaking wrote

Same journal: AI cover art which makes no sense? Oooh!

23.11.2025 01:51 πŸ‘ 197 πŸ” 42 πŸ’¬ 5 πŸ“Œ 2
Post image

Calling on my #science network! TeamNDF is #hiring a postdoc to start in 2026!

Are you fascinated by metabolism and the brain? Do you want to dig into life long impacts and the molecular cause?

Learn more about the team and our research here: www.dife.de/en/research/...

Please share! 🧠 πŸ” πŸ’‰

22.11.2025 12:15 πŸ‘ 8 πŸ” 12 πŸ’¬ 0 πŸ“Œ 1
Video thumbnail

New on bioRxiv! 🚨
β€œPericyte and Endothelial Primary Cilia and Centrioles have Disparate Organization Across the Brain Microvasculature”
This project studying #microvascular cells took an unexpected turn when we discovered that #pericytes have primary #cilia!
πŸ”— www.biorxiv.org/content/10.1...
πŸ§ͺ 🧡1/8

20.11.2025 21:03 πŸ‘ 38 πŸ” 11 πŸ’¬ 1 πŸ“Œ 2
Post image

We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji.

It ships many new features, detailed below, but that are articulated around the following:

20.11.2025 11:42 πŸ‘ 182 πŸ” 76 πŸ’¬ 4 πŸ“Œ 7

Das ist ein ganz kleiner Teil einer Langerhans'schen Insel, die unseren Blutzuckerspiegel reguliert. Eine Insel besteht aus etwa 1000 hormonproduzierenden Zellen. Man sieht in der Animation 2 Betazellen (mit Insulin) einen Teil eines BlutgefÀßes und einen Teil einer Nervenzelle (Axon).

17.11.2025 18:57 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Post image

My new ImageJ / Fiji toolkit is out πŸ”₯! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...

04.11.2025 22:40 πŸ‘ 202 πŸ” 63 πŸ’¬ 4 πŸ“Œ 5

As a neuroscientist, I’d suggest there is a profound disconnect between what *some* computer scientists think is representative of β€œintelligence”, cognitive ability, or descriptions of consciousness from some in AI work.

LLMs are not how neural systems process information, nor how brains function.

06.11.2025 17:19 πŸ‘ 242 πŸ” 84 πŸ’¬ 20 πŸ“Œ 8
Dodonova Group – Organisational principles and 3D architecture of archaeal chromatin

We are looking for motivated #postdocs to join the lab! Biochemistry/microbiology/cryo-EM experience? Excited by #cryo-EM/ET, #chromatin? β„οΈπŸ§¬πŸ§«
Interdisciplinary projects, top EMBL facilities!
Email CV + short cover letter β†’ svetlana.dodonova@embl.de
Info about the group: www.embl.org/groups/dodon...

15.10.2025 10:38 πŸ‘ 9 πŸ” 7 πŸ’¬ 0 πŸ“Œ 1

Everything you wanted to know about #cilia & #signaling in one big beautiful poster format from field thought leaders @wachtenlab.bsky.social & @sorentc.bsky.social- from our just live @jcellsci.bsky.social Special Issue… 🀩🀩🀩

30.10.2025 13:11 πŸ‘ 14 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0