It’s the HP lattice model of folding that Ken Dill used a lot in the 80s and 90s. It’s so established, there’s no need to have the amino acids. Plus, I just looked at the corrected figure, and there’s *still* a mistake in a different of the same figure — they show a chain with a branch.
I’m wondering why this would ever be a figure anyway? I mean, why would you need the amino acid structures as a paper figure, given they can be found trivially in dozens (hundreds) of places online?
Me too. I love the Fionavar tapestry (and the sly references to it in other books).
Also, I just finished Under Heaven a few hours ago.
Cell Press has their own version of this, where you can submit to multiple journals simultaneously. It sort-of works — because I don’t pick the reviewers or know their identifies, I don’t know how much to trust their reviews and end up needing to essentially re-review the paper myself.
Got it — thanks!
I’m confused by the percentages in that graphic, since there are non-overlapping categories (e.g. no one writes a paper in endnote or zotero, though I suppose you *could* write a paper directly on github). What was the prompt that led to that data?
8 people at a long table covered with Chinese dumplings
Rochester reunion dinner at #bps2026. Some current lab members, former Mathews lab members, and lab friends. Dumplings and science talk for the win!
Neither— we think they modulate trafficking of the active gpcr by beta arrestins. As far as we can tell, they don’t bind to the gpcr at all.
Dammit, you’re right
Emily just gave an excellent talk on the same work. #bps2026
My former student Dr. Emily Weed-Nichols is presenting her poster on computationally characterizing new compounds to treat opioid overdose today. Come check it out at B45!
#bps2026
A scientific poster describing loos, a suite of tools for analyzing molecular simulations
If you’re interested in developing new methods to analyze molecular simulations, come see my poster today at B400. 
#bps2026
a man presenting a poster with a blue banner to a woman
My student @aksharasharma.bsky.social is presenting his work on pKa shifts in ionizable lipids at B192
#bps2026
Jeremy’s talk was fantastic, but depressing. Sadly, it was more consistent with his blue sky feed then his scientific output. If you don’t follow him here (@jeremymberg), you should.
Waiting to hear @jeremymberg.bsky.social speak at #bps2026 about how to convey the value of biophysics to the public. I think the last time I heard Jeremy give a scientific presentation was when I was a graduate student and he taught NMR and FFTs.
If you’re at #bps2026, keep an eye out for editorial board members wearing “tell me about your poster” buttons. We can advise you about submitting your work to Biophysical Journal @biophysj.bsky.social and we can discount the publication fees.
Oops, forgot to tag @emilyweednichols.bsky.social
I’m sure I’ll run into you at some point! #bps2026
#CPOW sponsored PI to PI mixer today at #BPS2026 @biophysicalsoc.bsky.social
My former student Dr. Emily Weed-Nichols is presenting her poster on computationally characterizing new compounds to treat opioid overdose today. Come check it out at B45!
#bps2026
Ironically, Rochester is only expecting 3-4”.
My parents in Westchester said they were expecting about 15”.
That’s what my institution has done. It’s got its own issues — smaller graduate programs are arguably below critical mass now — but at least we’re not betraying the students we admit.
Also, that sounds more like a qualifying exam thing. At least in my experience, PhD defenses are almost entirely focused on what you did and where you see the work going in the future.
Thanks for sharing! I think that was from before I started consistently reading your work.
Summon @dereklowe.bsky.social for a better discussion, but as I understand it, getting good candidate molecules isn’t the expensive part of drug design. Testing for safety and efficacy is orders of magnitude more expensive, and this company doesn’t touch that part.
Totally agree. One of my favorite things about being in a relationship is cooking for (or with) someone.
That’s worse somehow, especially since Greece isn’t really a city, just a suburb or Rochester.
I just did the dumbest thing of my entire career to prove a much more serious point.
I tricked ChatGPT and Google, and made them tell other users I’m a competitive hot-dog-eating world champion
People are using this trick on a massive scale to make AI tell you lies. I’ll explain how I did it
