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birtehoecker.bsky.social

@birtehoecker

Biochemist at Bayreuth University, Germany, interested in protein evolution & design

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02.02.2024
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Latest posts by birtehoecker.bsky.social @birtehoecker

🚨 Registration open!
Join us next April on the Belgian coast πŸ‡§πŸ‡ͺ for the FEBS Advanced Course β€œGenerative AI for Protein Engineering” 🧬
A unique, hands-on week dedicated to thinking and designing like a protein engineer.

πŸ‘‰ Info & apply: …proteinengineering2026.febsevents.org
#ProteinDesign

05.11.2025 17:43 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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The Key to Enzymatic Degradation of Polybutylene Terephthalate (PBT): Influence of Semicrystalline Properties on Degradation This study demonstrates that enzymatic degradation of polybutylene terephthalate (PBT) can be achieved by tuning PBT's semicrystalline properties and incubation conditions. Polymers with a high conte....

πŸ“£New CRC 1357 Publication: The Key to Enzymatic Degradation of Polybutylene Terephthalate (PBT): Influence of Semicrystalline Properties on Degradation
doi.org/10.1002/cssc...

03.11.2025 16:29 πŸ‘ 3 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
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A third type of PETase from the marine Halopseudomonas lineage The enzymatic degradation of polyethylene terephthalate (PET) offers a sustainable solution for PET recycling. Over the past two decades, more than 100 PETases have been characterized, primarily exhi...

πŸ“£New CRC 1357 Publication: Congrats to Onur Turak, Protein Design @birtehoecker.bsky.social, & co-authors and their new article: A third type of PETase from the marine Halopseudomonas lineage
Structure & sequence features of type III PETases reported!
onlinelibrary.wiley.com/doi/10.1002/...

30.09.2025 11:54 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Customizing the Structure of a Minimal TIM Barrel to Craft a De Novo Enzyme The TIM barrel is the most prevalent fold in natural enzymes, supporting efficient catalysis of diverse chemical reactions. While de novo TIM barrels have been successfully designed, their minimalisti...

In collaboration with @birtehoecker.bsky.social, we’ve unlocked enzymatic activity in a minimal de novo TIM barrel by designing a custom lid for catalysis! πŸ§΅πŸ‘‡
#ProteinDesign #EnzymeDesign

Customizing the Structure of a Minimal TIM Barrel to Create a De Novo Enzyme
www.biorxiv.org/content/10.1...

29.07.2025 18:33 πŸ‘ 12 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Members of EU Rosetta Con 2024

Members of EU Rosetta Con 2024

Early bird registration for 𝐄𝐔 π‘π¨π¬πžπ­π­πš 𝐂𝐨𝐧 πŸπŸŽπŸπŸ“ is open! πŸŽ‰πŸŽ‰πŸŽ‰

Come join us for three days of protein design fun! (October 20-22, 2025)

Direct registration link: pretix.eu/SBD/RCon2025/
Website: europeanrosettacon.org

We are looking forward to seeing you!

Please share this far and wide:)

26.06.2025 16:29 πŸ‘ 9 πŸ” 4 πŸ’¬ 0 πŸ“Œ 3
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We proudly present our GBM-Master awardee 2025: Emma DΓΌthorn. Emma did her thesis in the Mustroph lab and finished 1st in the Bayreuth MSc in Biochemistry & Mol.Biology. We also enjoyed a great GBM lecture by Clara Schroeder (Uni Leipzig) and the Bayreuth JuniorGBM summer party! @gbmev.bsky.social

25.06.2025 21:30 πŸ‘ 6 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1
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Two great weeks at the beautiful UNSW campus in Sydney come to an end - lots of fun discussions with the Curmi lab about protein motors and how to design artificial ones!

13.04.2025 03:24 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Great talks & discussions at the 76th Mosbacher Kolloquium last week - in particular fantastic Lynen Lecture by Tanja Kortemme @kortemmelab.bsky.social and Eduard-Buchner award lecture by Dorothee Kern! And great to see so many old and new friends. @gbmev.bsky.social

24.03.2025 21:55 πŸ‘ 17 πŸ” 8 πŸ’¬ 1 πŸ“Œ 0
Benedict Wolf with his FEBS poster prize, awarded by H. Kolmar

Benedict Wolf with his FEBS poster prize, awarded by H. Kolmar

Julian Beck Wolf with his GBM poster prize, awarded by H. Kolmar

Julian Beck Wolf with his GBM poster prize, awarded by H. Kolmar

Lisa Schmidt with her GBM poster prize, awarded by H. Kolmar

Lisa Schmidt with her GBM poster prize, awarded by H. Kolmar

Meet our three poster prize winners that were awarded by GBM president Harald Kolmar: Benedict Wolf (Heidelberg), Julian Beck (Bayreuth) and Lisa Schmidt (Berlin). Thank you
@febsopenbio.bsky.social for supporting us!

24.03.2025 16:12 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Janosch Hennig and Dorothee Kern

Janosch Hennig and Dorothee Kern

Congratulations Dorothee! Laudatio given by Janosch Hennig, co-organizer of the meeting.

21.03.2025 17:13 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Feodor-Lynen-Lecture delivered by Tanja Kortemme (UCSF) at the Mosbacher Kolloquium. Congratulations!

20.03.2025 18:44 πŸ‘ 18 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
GBM Lunch on February 12 (12:30): Lukas Milles talk about the Reconstructing biological function with de novo protein design

GBM Lunch on February 12 (12:30): Lukas Milles talk about the Reconstructing biological function with de novo protein design

Join us for the #GBMLunch
πŸ“… February 12 πŸ•› 12:00 PM
Lukas Milles @lfmilles.bsky.social from the Gene Center of LMU & MPI of Biochemistry, Munich will be presenting on:

β€œReconstructing biological function with de novo protein design”

The session will be chaired by @birtehoecker.bsky.social

06.02.2025 11:03 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Flyer for a Benzon Symposium on Protein structure prediction and design in biology and pharmacology (Sept. 1–4, 2025). Speakers include: Gabriel Rocklin, Birte HΓΆcker, Amy Keating, Tanja Kortemme, Bruno Correia, Sarel  Fleishman, Ashutosh Chilkoti, Minkyung Baek, Noelia Ferruz, James Fraser, Alan  Moses, Susan Marqusee, Ben Lehner, Mohammed AlQuraishi, Dek Woolfson, Gustav Oberdorfer, Hannah Wayment-Steele, Ora Schueler-Furman, Jenifer Listgarten, Alexander Rives, & Max Bonomi.

Flyer for a Benzon Symposium on Protein structure prediction and design in biology and pharmacology (Sept. 1–4, 2025). Speakers include: Gabriel Rocklin, Birte HΓΆcker, Amy Keating, Tanja Kortemme, Bruno Correia, Sarel Fleishman, Ashutosh Chilkoti, Minkyung Baek, Noelia Ferruz, James Fraser, Alan Moses, Susan Marqusee, Ben Lehner, Mohammed AlQuraishi, Dek Woolfson, Gustav Oberdorfer, Hannah Wayment-Steele, Ora Schueler-Furman, Jenifer Listgarten, Alexander Rives, & Max Bonomi.

πŸ“£ Save the dates πŸ“…

We are organizing a Benzon Symposium on "Protein structure prediction and design" with what I think is an amazing set of speakers

Meeting will take place in Copenhagen πŸ‡©πŸ‡° on Sept. 1–4, 2025, and abstract submission will open in March (benzon-foundation.dk/benzon-sympo...)

13.12.2024 14:51 πŸ‘ 92 πŸ” 30 πŸ’¬ 1 πŸ“Œ 2
Poster Mosbacher Kolloquium MΓ€rz 2025

Poster Mosbacher Kolloquium MΓ€rz 2025

Registration is open: 76. Mosbacher Kolloquium "AI-driven (r)evolution in structural biology & protein design" from 20.03.2025–22.03.2025
mosbacher-kolloquium.org
Early registration: January 31, 2025
Poster abstracts: January 31, 2025
Please RT!

03.12.2024 14:42 πŸ‘ 11 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1