John F. Cryan's Avatar

John F. Cryan

@jfcryan

VP Research & Innovation, University College Cork @ucc.ie @uccresearch.bsky.social |PI @apcmicrobiomeirel.bsky.social |Prof Dept. Anatomy & Neuroscience |MRIA @ria.ie| Stress, Microbiota-Gut-Brain Axis, Brain-Body Interactions, Research Policy

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18.09.2023
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Latest posts by John F. Cryan @jfcryan

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Feeding gut microbes to nourish the brain: unravelling the diet–microbiota–gut–brain axis - Nature Metabolism This Review provides an overview of the interplay between host diet and the gut microbiota, and how this affects brain function.

#Throwback 🧪

REVIEW | Feeding gut microbes to nourish the brain: unravelling the diet–microbiota–gut–brain axis

@elizschneider.bsky.social‬, ‪@jfcryan.bsky.social et al

26.02.2026 18:01 👍 12 🔁 5 💬 0 📌 0
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The big lecture is drawing near. While #Monahan26 is free of charge, registration is essential. Send an email to government@ucc.ie 👍.

@ucc.ie @corkbeo.bsky.social @joh2024.bsky.social @jfcryan.bsky.social @theresareidy.bsky.social @irishtimes.com

28.02.2026 12:09 👍 4 🔁 2 💬 0 📌 0
An unhealthy diet disrupts feeding behavior and the gut microbiota, but
whether early-life dietary effects persist, or can be restored later in life,
remains unclear. We investigated whether microbiota-targeted interventions
(FOS + GOS or Bifidobacterium longum APC1472) could restore early-life highfat/
high-sugar (HFHS) diet-induced feeding alterations in adult female and
male mice.

An unhealthy diet disrupts feeding behavior and the gut microbiota, but whether early-life dietary effects persist, or can be restored later in life, remains unclear. We investigated whether microbiota-targeted interventions (FOS + GOS or Bifidobacterium longum APC1472) could restore early-life highfat/ high-sugar (HFHS) diet-induced feeding alterations in adult female and male mice.

New APC paper in Nature Comms
First author Cristina Cuesta-Marti and colleagues examine how eating unhealthy foods early in life leaves lasting brain and feeding changes but bacteria can help restore healthy eating.

www.nature.com/articles/s41...
#Microbiome #GutBrainAxis
Tagging collaborators ⬇️

24.02.2026 11:06 👍 9 🔁 7 💬 1 📌 0
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If you missed @jfcryan.bsky.social and Ted Dinan talking with Síle Seoige on @tg4.bsky.social last night, you can watch in on the player. They are talking about their research on gut feelings and #anxiety.
#microbiome #gutbrainaxis
@uccresearch.bsky.social

21.02.2026 14:15 👍 8 🔁 2 💬 0 📌 0
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What a great way to kick off our UCC Futures Lecture Series with Agustin Ibanez on campus talking about “Rethinking Brain Aging in the Big Data World” - Neuroscience meets Social Science meets Big Data

@moloneyger.bsky.social @bvalderrama.bsky.social @uccresearch.bsky.social

20.02.2026 22:45 👍 10 🔁 1 💬 0 📌 0
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If you missed @jfcryan.bsky.social and Ted Dinan talking with Síle Seoige on @tg4.bsky.social earlier this week catch it again 𝐭𝐨𝐧𝐢𝐠𝐡𝐭 𝐚𝐭 𝟗𝐩𝐦 . They talking about their research on gut feelings and #anxiety.
#microbiome #gutbrainaxis
@uccresearch.bsky.social

20.02.2026 15:33 👍 5 🔁 1 💬 0 📌 0
Pages 20-21 of the Ticket from the Irish Times with a review of Irish Romanticism: A Literary History by Claire Connolly.

Pages 20-21 of the Ticket from the Irish Times with a review of Irish Romanticism: A Literary History by Claire Connolly.

Very pleased with my first piece for the @irishtimes.com - a review of @claireconnolly.bsky.social new book, Irish Romanticism: A Literary History. Thank you @martindoyle.bsky.social for the opportunity!

31.01.2026 14:10 👍 26 🔁 4 💬 0 📌 1
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Congratulations to wonderful colleague @claireconnolly.bsky.social on her new book, Irish Romanticism: A Literary History, launched this evening by @jfcryan.bsky.social, VP for Research & Innovation @ucc.ie, and Prof. Clair Wills, King Edward VII Prof. of English Literature at Cambridge.

19.02.2026 18:19 👍 24 🔁 6 💬 1 📌 0
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What a great way to end the week! Thanks @jfcryan.bsky.social for the fantastic talk and discussion ! We are all delighted here @cbitoulouse.bsky.social

13.02.2026 17:02 👍 3 🔁 1 💬 0 📌 0
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Fascinating new link between stress, liver tryptophan metabolism, and liver cancer in this new article @natmetabolism.nature.com www.nature.com/articles/s42...

We unpack it in our Nature Metabolism News & Views with John Cryan & Gerard Clarke, have a read: rdcu.be/eZHvs

19.01.2026 15:37 👍 5 🔁 3 💬 0 📌 0
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New APC paper in the Journal of Human Nutrition & Dietetics.
First author Aimone Ferri and colleagues validate a tool to measure fermented food intake. The study forms part of the research programme of @jfcryan.bsky.social group at APC.
doi.org/10.1111/jhn....
#microbiome #ucc #teagasc #kefir

04.02.2026 11:39 👍 1 🔁 2 💬 1 📌 0
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From Fork to Feelings: How Foods Shape Mental Health via the Microbiota–Gut–Brain Axis

Latest review out in @annualreviews.bsky.social -Well done Aimone Ferri, Laise Paes & @elizschneider.bsky.social

www.annualreviews.org/content/jour...
@apcmicrobiomeirel.bsky.social @anatneuroucc.bsky.social

03.02.2026 22:30 👍 22 🔁 9 💬 1 📌 1
Promotional image for the European University Association's analysis of the European Commission's Horizon Europe 2028-2034 proposal, featuring an abstract blue-toned background of architectural glass structures.

Promotional image for the European University Association's analysis of the European Commission's Horizon Europe 2028-2034 proposal, featuring an abstract blue-toned background of architectural glass structures.

Expanding Horizon Europe’s Pillar III is very welcome, but researchers and universities are absent from this part of the Commission’s #FP10 proposal.
🏛️ Universities should be explicitly recognised and included as participants.
📄 Our analysis: https://bit.ly/4nxoFL4

28.01.2026 11:33 👍 1 🔁 1 💬 0 📌 0
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Nice reading to refresh the knowns and unknowns on feeding gut microbes to nourish the brain

Kudos to @jfcryan.bsky.social , @elizschneider.bsky.social  et al.

@natmetabolism.nature.com 
https://www.nature.com/articles/s42255-024-01108-6

21.01.2026 07:36 👍 6 🔁 2 💬 1 📌 0
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So proud of @rabal97.bsky.social who successfully defended her PhD yesterday. Her work on fermented foods was an outstanding collaborative effort between @pauldcotter.bsky.social lab at Teagasc and my own.

Huge thanks to her excellent Examiners @mireiavallesc.bsky.social & Aonghus Lavelle

21.01.2026 13:30 👍 9 🔁 1 💬 0 📌 1
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The Microbiota Shapes Central Nervous System Myelination in Early Life
Really excited to see this paper out-A great cross-species collaboration with David Lyons, Edinburgh & Iiris Hovatta Helsinki.
Huge kudos to former PhD student Caoimhe Lynch et al advanced.onlinelibrary.wiley.com/doi/10.1002/...

20.01.2026 16:06 👍 16 🔁 8 💬 1 📌 0
Preview
Gut Microbes Play a Role in Early Brain Development | University College Cork Learn, Study and Research in UCC, Ireland's first 5 star university. Our tradition of independent thinking will prepare you for the world and the workplace in a vibrant, modern, green campus.

A new research study has uncovered a previously unknown role that our gut plays in regulating early brain development.

The study, led by researchers from @apcmicrobiomeirel.bsky.social @ucc.ie, is published in the prestigious international journal Advanced Science.

www.ucc.ie/en/research/...

20.01.2026 10:57 👍 7 🔁 3 💬 0 📌 0
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I'm pleased to share our newest publication where we developed and validated a questionnaire to assess fermented food intake, led by PhD student and dietitian Aimone Ferri!

lnkd.in/duU8Jfd2

@jfcryan.bsky.social @pauldcotter.bsky.social @rabal97.bsky.social

19.01.2026 12:49 👍 7 🔁 2 💬 1 📌 1
180 Years of Research at University College Cork
180 Years of Research at University College Cork YouTube video by UCC Research

We are delighted to present a short video celebrating 180 years of research and innovation at University College Cork @ucc.ie

"From our past to UCC Futures -UCC's legacy of research excellence is just beginning"
@uccalumni.bsky.social
youtu.be/W_IwYJYHqcI

19.01.2026 08:53 👍 4 🔁 0 💬 0 📌 0
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Huge congrats to Brendan Sharvin on a tour de force PhD defence today -a performance that showcased the depth, rigour, and originality of the work. We couldn’t be prouder of all you’ve achieved.

Thanks to @peppeganga.bsky.social and Jane English for being excellent examiners 👏

16.01.2026 14:30 👍 32 🔁 1 💬 0 📌 0
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UCC researchers unveil 'world-first tool' aimed at persuading Grok users to avoid creating explicit images Free 10-minute intervention dubbed ‘Deepfakes/Real Harms’ has been designed to reduce the willingness of users to engage with harmful uses of deepfake technology, like creating non-consensual explicit...

"The free 10-minute intervention dubbed ‘Deepfakes/Real Harms’ has been designed to reduce the willingness of users to engage with harmful uses of deepfake technology, like creating non-consensual explicit content", research by John Twomey supported by Lero
www.irishexaminer.com/news/arid-41...

16.01.2026 10:46 👍 5 🔁 3 💬 0 📌 0
180 Years of Research at University College Cork
180 Years of Research at University College Cork YouTube video by UCC Research

UCC: 180 years fuelling research & innovation.

UCC Futures continues to empower thinkers, makers, and leaders to shape tomorrow. At UCC, the future isn’t just imagined, it’s created.

@jfcryan.bsky.social | @uccinnovation.bsky.social | @ucc.ie

youtu.be/W_IwYJYHqcI

15.01.2026 11:00 👍 5 🔁 3 💬 0 📌 0
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Research Ireland and the Arts and Humanities Research Council (AHRC) have launched a new research programme that will deliver transformational impact on creative economy research between the UK and Ireland. Deadline to apply is 24th March 2026. For more visit: www.researchireland.ie/funding/crea...

13.01.2026 14:35 👍 7 🔁 8 💬 0 📌 0

Birth by Cesarean Section Remodels Neonatal Brain Barriers and Associated Immune and Metabolic Pathways in Mice https://www.biorxiv.org/content/10.64898/2026.01.06.696394v1

07.01.2026 15:15 👍 3 🔁 2 💬 0 📌 0
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Congrats to Naomi Gavioli on successfully defending her PhD today and bringing exactly 4 years in @apcmicrobiomeirel.bsky.social @anatneuroucc.bsky.social @ucc.ie to a close. Huge thanks to Examiners Michelle Roche & Friederike Uhlig for such a great discussion.

07.01.2026 18:30 👍 141 🔁 14 💬 6 📌 0
Preview
Feeding gut microbes to nourish the brain: unravelling the diet–microbiota–gut–brain axis - Nature Metabolism This Review provides an overview of the interplay between host diet and the gut microbiota, and how this affects brain function.

#Throwback 🧪

REVIEW | Feeding gut microbes to nourish the brain: unravelling the diet–microbiota–gut–brain axis

@elizschneider.bsky.social‬, ‪@jfcryan.bsky.social et al

31.12.2025 19:08 👍 24 🔁 8 💬 1 📌 0
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#12DaysofIrishResearch: A Brush with Climate, led by Dr Maria Kirrane (@ucc.ie), empowers hairdressers to spark conversations on sustainability and climate action. One of 40 projects funded under the Research Ireland Discover Programme. Read more: https://pulse.ly/xeyxg9c5ua

21.12.2025 12:59 👍 8 🔁 2 💬 0 📌 0
Redirecting

Our new paper identifies microbial tryptophan metabolites and their concentration ranges that influence both blood-brain and gut barriers integrity in vitro.

doi.org/10.1016/j.ns...

@apcmicrobiomeirel.bsky.social
@inspiremsca.bsky.social

@sarah-janeleigh.bsky.social
@jfcryan.bsky.social

02.12.2025 10:14 👍 1 🔁 1 💬 0 📌 0
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LEADING THE WAY has had some incredible reviews 🔥. It will be launched by Lord Mayor, Councillor Fergal Dennehy, in City Hall at 6.30pm on Thursday 11 December.

@ucc.ie @joh2024.bsky.social @jfcryan.bsky.social @corkbeo.bsky.social @what-if-cork.bsky.social

29.11.2025 15:12 👍 5 🔁 2 💬 0 📌 0
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Delighted to speak at the launch of four books 📕 📕📕📕from UCC Futures: Collective Social Futures Scholar's today as a primer for the Festival of Social Science at University College Cork @ucc.ie @uccresearch.bsky.social

24.11.2025 23:23 👍 11 🔁 0 💬 1 📌 0