Fernando Bazan's Avatar

Fernando Bazan

@jfernandobazan

curious about all things bio & solving tricky structural puzzles / mlbio for protein design, engineering & drug disco / cytokine immunologist / stanfordberkelyucsf & dnaxgenentech / recovering twit

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12.09.2023
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Latest posts by Fernando Bazan @jfernandobazan

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Kate Jarvik Birch (American Artist, born 1977)
"Red Cup of Espresso", 2025.
Gouache on Paper, 6 Γ— 6 inches.
Private Collection.

#art #painting #artist #BlueSkyArt

11.03.2026 11:20 πŸ‘ 73 πŸ” 13 πŸ’¬ 1 πŸ“Œ 2
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β€œMinnesota's nickname is the North Star State due to its motto "L'Etoile du Nord," which was adopted in 1861.

Minnesota is the North Star State. ✨

Consider this fact whenever you're feeling despair at what's happening in our country right now. Follow our North Star.”

- Mari Talkin

01.02.2026 05:15 πŸ‘ 2532 πŸ” 488 πŸ’¬ 0 πŸ“Œ 0
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Peter EugΓ©n (Sweden Artist, born 1978)
"Tree and Boat in Lake", 2024.
Watercolor, 30 Γ— 40 cm.
Private Collection.

#art #painting #artist #BlueSkyArt

01.02.2026 11:59 πŸ‘ 191 πŸ” 21 πŸ’¬ 1 πŸ“Œ 0
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Hallmarks of cancerβ€”Then and now, and beyond Hanahan revisits the evolving framework of cancer hallmarks, synthesizing 25 years of conceptual refinement into a multidimensional view of tumor biology. This review highlights how aberrant capabilit...

Follow up to Doug Hanahan’s visionary article about the stages of cancer development from back in the 1990s

www.cell.com/cell/fulltex...

30.01.2026 19:30 πŸ‘ 29 πŸ” 13 πŸ’¬ 1 πŸ“Œ 0
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Mitotic entry: Bora takes Polo to Aurora, and gives them a hug - The EMBO Journal The EMBO Journal - Cell division involves the complete reorganization of the cellular architecture, requiring precise coordination of cellular processes in space and time, but how does this control...

See also the great News&Views comment by Monica Gobran and @plenart.bsky.social - highlighting all three papers!
link.springer.com/article/10.1...

28.01.2026 14:48 πŸ‘ 16 πŸ” 12 πŸ’¬ 1 πŸ“Œ 0
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Mirdita Lab - Laboratory for Computational Biology & Molecular Machine Learning Mirdita Lab builds scalable bioinformatics methods.

My time in @martinsteinegger.bsky.social's group is ending, but I’m staying in Korea to build a lab at Sungkyunkwan University School of Medicine. If you or someone you know is interested in molecular machine learning and open-source bioinformatics, please reach out. I am hiring!
mirdita.org

20.01.2026 11:07 πŸ‘ 104 πŸ” 55 πŸ’¬ 7 πŸ“Œ 1
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TomΓ‘s SΓ‘nchez, Ojo de aguas
Tempera on paper, 2005
22,5 x 30 cm | 8 Β³/β‚„ x 11 ΒΉΒ³/₁₆ in

20.01.2026 01:06 πŸ‘ 64 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0
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In remembrance of Peer BorkΒ  | EMBL EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.

Very sad to hear about the passing of Peer Bork, one of true giants of computational biology

www.embl.org/news/embl-an...

16.01.2026 19:43 πŸ‘ 22 πŸ” 9 πŸ’¬ 1 πŸ“Œ 0
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Happy to finally share the amazing results of our long-term collaboration with Karin Reinisch’s lab on how bridge lipid-transfer proteins (BLTPs) cooperate with partner proteins to orchestrate lipid delivery. A quick thread (1/7)
www.biorxiv.org/content/10.6...

12.01.2026 19:57 πŸ‘ 101 πŸ” 39 πŸ’¬ 5 πŸ“Œ 1
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Disulfide engineering reveals unexpected pro- and anti-aggregation conformers of human Ξ±-synuclein Intrinsically disordered proteins can aggregate in many distinct conformations (polymorphs). Polymorphs are a striking example of fold-switching: one primary structure able to form distinct tertiary s...

Proud to share our newest preprint. We introduced conformational constraints (disulfides) into alpha-synclein and measured effects on aggregation. There were surprises, including a possible new amyloid polymorph and a substoichiometric chaperone-like aggregation inhibitor.
doi.org/10.64898/202...

09.01.2026 05:39 πŸ‘ 5 πŸ” 1 πŸ’¬ 1 πŸ“Œ 1
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My painting DARK STORM

07.01.2026 18:53 πŸ‘ 4165 πŸ” 415 πŸ’¬ 125 πŸ“Œ 16
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When RNA Degradation 🀝 meets 🀝 Protein Degradation! tinyurl.com/E3TDMD In a collaboration of @bartellab.bsky.social and Schulman lab, we show that, in target-directed microRNA degradation (TDMD), 2-RNA-factors recruit an E3 ligase and induce the degradation of not only a protein but also RNA (1/5).

06.01.2026 08:04 πŸ‘ 117 πŸ” 50 πŸ’¬ 1 πŸ“Œ 4
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Orange slices #oilpainting #art

07.01.2026 00:45 πŸ‘ 7405 πŸ” 720 πŸ’¬ 115 πŸ“Œ 19

Nice description of ipTM problems & how actifPTM, LIS, & ipSAE fix those for scoring protein-protein interactions.

New script on ipSAE github: af2rechain.py takes an input AF2 model of one protein & breaks it into chains given domain boundaries for input to ipSAE to calculate intraprotein ipSAE.

03.01.2026 00:10 πŸ‘ 18 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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LΓ‘szlΓ³ Moholy-Nagy. 7am, New Year’s Morning, Berlin, 1930

31.12.2025 17:39 πŸ‘ 223 πŸ” 46 πŸ’¬ 3 πŸ“Œ 4
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Franco Matticchio (Italian Artist, born 1957)
"The Pillow and surroundings", 2016.
Illustration.
#art #painting #artist #BlueSkyArt

24.12.2025 04:23 πŸ‘ 189 πŸ” 29 πŸ’¬ 1 πŸ“Œ 2
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Single-cell glycome and transcriptome profiling enabled by a library of anti-glycan antibodies Marglous et al. generated a database of anti-glycan antibody sequences, expressed and characterized a library of 154 antibodies, and generated DNA-barcoded antibodies for single-cell transcriptome and glycome profiling. Glycans associated with cancer stem cells and metastasis were uncovered, demonstrating utility for basic and clinical research.

Online now! Online now! Single-cell glycome and transcriptome profiling enabled by a library of anti-glycan antibodies #chembiol

15.12.2025 16:30 πŸ‘ 12 πŸ” 4 πŸ’¬ 0 πŸ“Œ 2
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Hiroo Isono ( 1945-2013) japanese painter and illustrator, known for his intricate and fantastical scenes of tropical jungles and animals.
#art #painting #artist #BlueSkyArt

06.12.2025 12:01 πŸ‘ 94 πŸ” 15 πŸ’¬ 0 πŸ“Œ 0
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Pablo Picasso 1881-1973. Rafael Nogueras and a Friend at Els Quatre Gats Barscelona, 1899-1900. Oil on canvas. Tel Aviv Museum of Art.
#art #painting #artist #BlueSkyArt

06.12.2025 12:08 πŸ‘ 22 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Extrusive and cohesive cohesin cooperate to repair double-strand breaks in DNA @science.org @albertomarin.bsky.social @gerlichlab.bsky.social @imbavienna.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...

05.12.2025 03:28 πŸ‘ 30 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0
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Giovanna Raccosta (Italian Artist)
"Caffettiera", 2025.
Oil on Canvas Painting.
Private Collection.
#art #painting #artist #BlueSkyArt

05.12.2025 05:46 πŸ‘ 195 πŸ” 28 πŸ’¬ 2 πŸ“Œ 1
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Katja Lang (German, born 1968)
"Forest", 2018.
Drypoint Etching, 70.4 Γ— 50.1 cm.
Private Collection.

#art #painting #artist #BlueSkyArt

05.12.2025 06:42 πŸ‘ 51 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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John Philip Falter (American, 1910–1982)
"Snowy Ambush", 1959.
Oil on Paperboard laid down on Board,
61 Γ— 56.2 cm.
Private Collection.

#art #painting #artist #BlueSkyArt

05.12.2025 07:11 πŸ‘ 126 πŸ” 13 πŸ’¬ 1 πŸ“Œ 0
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Isabel Quintanilla (Spanish, 1938–2017)
"Sewing Room", 1974.
Oil on Board, 100 Γ— 82 cm.
Museo Thyssen-Bornemisza, Madrid, Spain.
#art #painting #artist #BlueSkyArt

02.12.2025 04:43 πŸ‘ 53 πŸ” 13 πŸ’¬ 0 πŸ“Œ 0
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Alessandro Tofanelli
(Italian painter, born 1959)
Latest Arrival, 2023.
Oil on Board
60 Γ— 60 cm
Private Collection

#art #painting #artist #BlueSkyArt

02.12.2025 07:10 πŸ‘ 31 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
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Gustav Wentzel
Sjakkspillere (Chess Players), 1886

08.02.2025 18:08 πŸ‘ 7 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Ray Morimura (Japanese Artist, born 1948)
"House in Tamugimata", 1999.
Japanese Woodblock Print, 45 Γ— 30 cm.
Private Collection.
#art #painting #painters #BlueSkyArt

22.08.2025 05:04 πŸ‘ 2609 πŸ” 431 πŸ’¬ 29 πŸ“Œ 6
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Eyvind Earle.
Black Evergreen Forest.
Serigraph, 1981.

29.11.2025 09:10 πŸ‘ 287 πŸ” 30 πŸ’¬ 2 πŸ“Œ 0
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Marian Dioguardi (American, b.1954)
"Mocha Espresso," n.d.
Oil on panel
24 x 24 in
#art #painting #artist #BlueSkyArt

28.11.2025 09:21 πŸ‘ 371 πŸ” 49 πŸ’¬ 5 πŸ“Œ 0

Best wishes for a prompt and painless tooth fix…but I’m very intrigued about your husband’s culprit crunchy cauliflower culinary craftwork! πŸ€”

29.11.2025 13:00 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0