GWAS Catalog API v1 retires in May 2026 🧬
Migrating to v2? It's faster, more stable, and gives you better query control.
Docs 👉 www.ebi.ac.uk/gwas/rest/api/v2/docs
Ref 👉 www.ebi.ac.uk/gwas/rest/api/v2/docs/reference
3 months to go
#genomics
Come say hi to our Technical Project Lead, Abayomi Mosaku and learn about our improved API! #FOG2026
The GWAS Catalog is at the Festival of Genomics! #FOG2026
Come to the Poster Zone to learn more about our new REST API, and join the 11.30am panel discussion to hear Principal Investigator Helen Parkinson talk about scaling #biodata
It’s a wrap!!
Our end of year break is now coming and we’ll be out of the office between 24th Dec and 1st Jan. Incoming helpdesk queries will be dealt with on 2nd Jan.
It's been a bumper year at the GWAS Catalog! A quick recap of what we added... #gwas #openscience
Wish it was easier to calculate PGS in trusted research environments (TRE) like DNAnexus or the All of Us workbench? Us to! We've been hard at work on a new version of pgsc_calc to make it more scalable in those TREs! Introducing pgsc_calc v3.0.0-alpha.1: pgsc-calc.readthedocs.io/en/v3-alpha.1/
Join us TODAY 12 noon ET/6pm CET to learn about the PEGASUS standard for predicted effector genes. Webinar link: hugeamp.org/news.html?ni...
Open Targets Platform 25.12 is out now!
Thanks to a GWAS Catalog update including 3 major studies using UK Biobank data, we now have over 1.4 million GWAS credible sets in the Platform.
Discover the data, feature, and technical updates in this release: blog.opentargets.org/open-targets... 🧬🖥️
It's on our roadmap to add tabulated case-control counts for all studies, but we can't give a timescale for that just yet. Great suggestion to add it to the browser, we'll keep that in mind!
🚨Reminder🚨
Accessing GWAS Catalog data programmatically? Try our new REST API with more features & improved design:
📖 Docs: www.ebi.ac.uk/gwas/rest/ap...
✎ Interactive workbook: tinyurl.com/5ak3hfzc
⏰ V1 deactivates May 2026 - migrate now!
#GWAS #GWASCatalog #Bioinformatics
The GWAS Catalog V2 REST API may have what you need: ebi.ac.uk/gwas/rest/ap... Please reach out to our helpdesk if you need more information!
We’re excited to keep developing PEGASUS together - join us and access materials on our GitHub community page !
👉 bit.ly/47QN07Y
A huge thank you to everyone who joined our #ASHG2🧬 ancillary session on the PEGASUS framework!
We were delighted to see such strong engagement and thoughtful discussion around Predicted Effector Genes (PEG) and our new framework⊞ - for representing gene prioritisation evidence🕵️ & conclusion📌.
Another month and lots of new & useful data added to www.PGSCatalog.org! Including new multi-ancestry insulin resistance scores, a score tailored for heart failure in East Asian individuals & more!
We recently passed 1 million curated SNP-trait associations!
See how the GWAS Diagram has changed with the significant data growth.
Contribute to our growing dataset and the diagram view by submitting your #SumStats and now also your top assoc. bit.ly/38rNSjx
What is the GWAS Catalog diagram?
🧬 Cytoband-trait association plot, now with:
✨ Non-overlapping in crowded regions
✨ Fully interactive (p ≤ 5e-8)
✨ Links to study, SNP & trait pages
✨ Filter by parent trait
🚨 NEWS! The GWAS Catalog Diagram is back up! 🚨
Smoother, faster loading for filtered views!
🗺️ Explore now 👉 www.ebi.ac.uk/gwas/diagram
Tell us what you think! Are there any features you would like? Help us to make it useful for the #gwas community
Want to recieve updates like this directly to your inbox? Sign up for our low-volume mailing list by sending an e-mail to gwas-announce-join@ebi.ac.uk with subject heading "subscribe" ✅
The split file facilitates analysis for users of Excel or other software which cannot handle >1m rows. Please note that data may continue to be added for previous years - you are advised to always work with the latest version of the complete file set. 👇
1. File now provided as a compressed .zip; data format unchanged.
2. Data split into multiple smaller files, and compressed together.
The split file (2) is divided by publication year, with a separate file for each year from 2023 onwards, and pre-2023 data in a single file. 👇
🚨 Using the GWAS Catalog “All associations” tsv download file? We recently made some changes that may affect your pipelines.
The data now includes >1m curated associations! This means the “All associations” file is extremely large!
In the latest release, you now have a choice of two formats 👇
Meet PEGASUS! Working on post-GWAS analyses to predict effector genes at GWAS loci? Come to room 259A 11:45 TODAY to find out more #ASHG25
I don't, but here is the abstract: meetings.ashg.org/event/ASHG25...
Fascinating work from Olivia Gray at #ASHG25. A great example of how including diverse samples is key to making the link between genetic architecture and biological mechanisms, and translation to clinic.
At #ASHG25 and want to meet members of the GWAS Catalog & PGS Catalog teams? Stop by the @impc-phenotypes.bsky.social booth 1420 where we're helping out!
🚨 Countdown to #ASHG25: Predicted Effector Gene standard is coming! 🚨 Join us and be part of the conversation!
📌 Poster Oct 16 | 2:30–4:30 | Poster Hall
🗓️ Session Oct 17 | 11:45–1:15 | Room 259A
Learn more: kpnashg2025.wordpress.com/pegs-workshop/
🧩 Toward a standard for Predicted Effector Genes → From PEG list to PEG matrix
Join us at #ASHG2025 to know about the work done and future directions!
WG materials: kp4cd.org/2024_PEG_wor...
Learn more: kpnashg2025.wordpress.com/pegs-workshop/
#ASHG25 #EffectorGene #PEGstandard #AncillarySession
GWAS finds millions of variants — but what are the Predicted Effector Genes (PEGs)? Our Nature Genetics Perspective rdcu.be/eoqVk showed big inconsistencies.
At ASHG 2025, we’ll introduce a new standard to make PEG data FAIR.
🗓️ Ancillary Session: Oct 17 | 11:45 | Room 259A
📌Poster: Oct 16 | 2:30
🌏 Shaping Together 🌏
Last year, we hosted a workshop on Predicted Effector Gene (PEG) lists - key data linking GWAS signals to biology
👉 kp4cd.org/2024_PEG_wor...
This #ASHG25, we share a proposed PEG standard
🗓️ Ancillary Session: Oct 17 | 11.45AM | Room 259A
📌Poster: Oct 16 | 2:30PM | Poster Hall
🚩1 MILLION curated associations!!! 🚩
Launched in 2008, took us 15 years to reach 500K, and thanks to your research and collaboration, we doubled the number in less than 3 years!
See some data insights tinyurl.com/mw53njbb
#OpenAccess
hi Rohit! Sorry for the slow reply - you can find all the information here: kp4cd.org/2024_PEG_wor... including a contact link to sign up the mailing list. We'd love to hear from you!
