Malu Murugan

Congrats arka! Beautiful work

Thanks @sfn.org. truly an honor.

Thank you ilana!

You are too kind Nicole! So good running into you!

Thanks Meenakshi!

Thanks Beth!

Thanks Vinny!

Happy to follow in your footsteps! :)

Thanks Anne!

Thanks kurt!

Thanks David

Thanks to my incredible mentors @ilanawitten.bsky.social and Rich Mooney, who have shaped me and my science. And thanks to my colleagues at Emory, who are simply the best!

I'm incredibly honored to receive the Janett Rosenberg Trubatch Career Development Award from @sfn.org SFN was the first research conference I ever attended and presented at. I feel truly humbled! Thanks to my fab research team who make me look good!

@hyma2194.bsky.social @soniakarkare.bsky.social @cemsevinc.bsky.social @jarildy.bsky.social

Happy Halloween!

Thanks David! We are really excited about this one.

Really fantastic work led by Ben Dykstra!

The data suggest distinct roles for iCA1 and iCA3 in how they represent social novelty information.

Finally, by tracking the same neurons across sessions, Ben found that, while spatial information remains stable across days - social information rapidly remaps in both hippocampal subfields.

Ben found that iCA3 neurons are more strongly modulated by social stimuli and encode relative social novelty relative to iCA1 neurons. In contrast, iCA1 neurons were more strongly modulated by spatial information..

So Ben developed a novel linear presentation assay which allows him to present multiple social targets at the same location using an automated programmable conveyor belt.

Ben found that both in the iCA1 and iCA3, social information is strongly multiplexed with spatial information. Making the traditional social discrimination assays hard to interpret.

Our newest preprint! Work led by Ben Dykstra (co-mentored by @gordonberman.bsky.social). Some of the first recordings from the iCA3 region during social behaviors. Ben found that iCA3 neurons more strongly represent social recognition information relative to iCA1 . www.biorxiv.org/cgi/content/...

What an incredible lineup!

Comparative gene editing reduces dopamine receptor levels across rodent species Translational challenges in neuroscience originate from species-specific differences that limit the generalizability of experimental findings. Comparative approaches can help distinguish conserved fro...

Very happy to share an expansion to the comparative gene editing toolkit: AAVs to reduce dopamine receptor levels that are functional in many rodent species. Fun collaboration with @malu-murugan.bsky.social, Elliott Albers and Frank Meye.

Yeah I was thinking that. It totally would be worth trying in the finches.

Reach out to Arjen if you want to try it out in your favorite model system. Congratulations to @soniakarkare.bsky.social and Dario Aspesi who did all the experimental work.

Comparative gene editing reduces dopamine receptor levels across rodent species Translational challenges in neuroscience originate from species-specific differences that limit the generalizability of experimental findings. Comparative approaches can help distinguish conserved fro...

Check out this exciting new tool from @ajboender.bsky.social - An aav based CRISPR-Cas9 strategy to knockdown dopamine receptors. Works in mice, voles and hamsters. It was a fun collaboration. www.biorxiv.org/content/10.1...

Beauty!

Congratulations! So well deserved!