The road ahead for uniQure: FDA says more data needed for AMT-130 gene therapy. On March 2026, uniQure shared in an update that current Phase 1/2 data weren’t enough for the agency. A new randomized, sham-controlled trial may be required.
Read the full article here:
en.hdbuzz.net/the-road-ahe...
We kindly received Watch your step, Mr Parkinson! by Frank Snowy Stinson
This book is a personal story of life with Parkinson’s. It is educational, encouraging and honest, touching on many issues of relevance to all those who are impacted by 'Parkee'.
Find the book here: www.watchyourstep.com.au
Our annual Parkinson's Disease Open day was on Saturday 14th February, which was a great success 🎉 We had talks about ongoing research projects, ways to get involved, and a patient perspective. A huge thank you to everyone involved with set up, speakers and all who attended!!
See here all the Parkinson's UK Cambridge Branch activities for 2026. Roger will be talking at the Branch on 28th August 10:30 – 12:30! Do come along, all are welcome 😊https://parkinsonscambridge.wordpress.com/about/
Registration and abstract submission are still open for the ISSCR 2026 Annual Meeting! It will take place in Montréal, Canada, 8-11 July 2026.Roger has now joined the Plenary Speaker line-up, He will be talking in 'Plenary IV: clinical advances and the promise for patients'.
www.isscr2026.org
On Tuesday 27th January Roger undertook the first of the Research Spotlight series 2026 with the World Parkinson Coalition, chatting to Simon Lewis about his research on Freezing of Gait.
See the interview here: youtu.be/XBKfeAMmvHU
Roger spoke for Cambridge Neurological Society on Tuesday!
He discussed how to take dopamine cell therapies to the clinic in Parkinson's Disease.
Follow Cam Neuro Soc (@camneurosoc Instragram) to get updates on monthly talks, all neurology and neurosurgery related.
Roger was a keynote speaker at the Open Targets Science Symposium being held at the Wellcome Genome Campus yesterday. He was talking about the trials and tribulations of dopamine cell therapies for PD at this hybrid meeting and had a wonderful time discussing this with a highly interactive audience.
Great session at the EHDN Platform Meeting - Is it time to target inflammation in Huntington's disease?
Roger gave an excellent presentation on “Inflammation in Huntington’s disease – Is there a case for it?”.
If you’re interested, check our our paper:
www.tandfonline.com/doi/full/10....
The recording for AD/PD™ Live Research Spotlight: "Phase I trial of hES cell-derived dopaminergic neurons for PD" is now available!
To watch first create an account: unlok-education.com/ad-pd
Then follow the link: adpd.unlok-education.com#/online-cour...
Roger is speaking in the upcoming AD/PD™ Live Research Spotlight: "Phase I trial of hES cell-derived dopaminergic neurons for PD"!
📅 29 January at 16:00 CET
🎓 Free and open to all healthcare professionals.
🔗 Register via link in bio: invt.io/1fxbcn6lk1z
#ADPDEducation #ADPDonUNLOK
Keep up to date with the World Parkinson Coalition with eNews! It has community updates and updates on the 7th @worldpdcongress.bsky.social happening in Phoenix in May 24th to 27th this year, anyone with an interest in Parkinson's is encouraged to come along!
www.linkedin.com/pulse/januar...
See here the BBC news article about The Bio-Hermes-002 study!
Roger is not involved in this study but as the Chair of Neurodegeneration at LifeArc he is excited to hear about this.
www.bbc.co.uk/news/article...
There is a new book out that discusses a patients journey with Parkinson's with a foreword by Roger!
Dancing with Parkinson’s Disease - Embracing Life After Diagnosis: A Practical Guide and Toolkit for Living Positively From Early Symptoms by Ian Guest
mybook.to/Iz54
New review article completed by Will and Roger! Eye manifestations in Huntington’s disease: an update on the potential of ocular biomarkers, Journal of Neurology. Really great work Will 🎉
rdcu.be/eYcah
Zanna's ACNR article review article with Greg Elder and others is now out! They discuss consumer-grade sleep wearables (eg. FitBits) and whether we should be using them in sleep research. Well done Zanna 🎉
See the article here: acnr.co.uk/articles/con...
On Monday 8th December Roger presented a live webinar with No Silver Bullet 4PD. In this session Roger guides us through the history and future of repairing the brain in PD. It is now available as a Podcast on all major Podcast providers! See here on Spotify: open.spotify.com/episode/1Qgt...
One of our patients has kindly knitted Roger a brain (to help with his work 😉)!
We are delighted to announce the publication of STEM-PD: a multi-centre, single-arm, first-in-human, dose-escalation trial, investigating the safety and tolerability of intraputamenal transplantation of human embryonic stem cell-derived dopaminergic cells for PD 🎉
bmjopen.bmj.com/content/15/1...
Roger is talking at the Parkinson's UK Royston and District Parkinson’s Group New Year Seminar next Monday 12th January 2026! The day will be 10am to 3pm with presentations by Roger, John Moylneux and Linda Bance. See details attached!
Many of us were at this magnificent concert by Serenata Female Voice in Trinity college chapel on the 21st December which was raising awareness and money for Parkinson's UK. A special shout out for Florence and Jamie who helped with it!
Last Friday our group went to The Green Man in Trumpington for a lovely Christmas meal!🎄🎉
On Tuesday 2nd December Roger undertook the last of the Research Spotlight series with the WPC, this time chatting to Dr David Standaert and Dr Karen L. Eskow Jaunarajs about Levodopa-induced dyskinesia's and Parkinson's.
Watch the interview here: www.youtube.com/watch?v=ZUqF...
Our group attended the Department of Clinical Neurosciences Cambridge Away day on Monday 15th December. Well done Sophie and Angelica for such great presentations and posters at the Away Day! And special congratulations to Angelica for winning 2nd prize for her poster 🎉
Tom Clowes and 3 other friends are doing the Talisker Rowing Challenge (The Toughest Rowing Race in the World). Rowing the Atlantic Ocean, 3,000 miles from the Canary Islands to Antigua to fundraise for @cureparkinsons.org.uk
See the full story or donate here: www.justgiving.com/page/thomas-...
Stem Cells and Parkinson’s: How Close Are We?
On Monday 8th December Roger presented a live webinar with Nosilverbullet4PD. In this session Roger separates hope from hype, guiding us through repairing the brain in PD.
Interested in listening, watch the webinar here: www.youtube.com/watch?v=hbap...
Check out these images created by our PhD student Jana! These are neurons extracted from brain tissue from surgery at Addenbrooke's hospital. She cultured the sample for 2 weeks and they have regrown neurites. Neurites are the long thin extensions from a neuron that allows communication.
'Is it time to target inflammation in Huntington’s disease?'
Save the date for EHDN's next platform meeting: Friday 30 January 2026, 13:30-15:00. Roger will be presenting, as well as Dr Niels Skotte then an expert panel discussion.
All are very welcome to attend!
us06web.zoom.us/webinar/regi...
Congratulations Jana for winning the Cambridge Stem Cell Institute Seed Funding Scheme 2026 🎉 The project is titled 'expanding multiplexing capabilities of confocal imaging systems using average arrival time-gating acquisition and unmixing'. We wish you all the best with the work!
I’m happy to share the paper “Phosphoproteomic profiling reveals post-translational dysregulation in Huntington’s disease patient-derived neurons,” is now live on Biorxiv. Thank you to all involved for the incredible teamwork and contributions in this paper!
www.biorxiv.org/content/10.1...
