Excited to share our latest work in @nature.com showing shared neural substrates for parenting and prosocial helping behavior. Full text available here: rdcu.be/e6PnY
04.03.2026 18:18
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Excited to share our latest work in @nature.com showing shared neural substrates for parenting and prosocial helping behavior. Full text available here: rdcu.be/e6PnY
Warm congratulations to The Brain Prize winners 2026, Professor David Ginty and Professor Patrik Ernfors, for their pioneering work on how the nervous system detects and processes touch and pain.
Karolinska Institutet
HHMI
#Neuroscience #BrainPrize2026
New paper from the lab led by @ericmulhall.bsky.social addresses how PIEZO1 and PIEZO2 are tuned to different types mechanical forces. From nanometer-scale super-resolution microscopy to in vivo experiments, links single-molecule observations to physiological function.
www.nature.com/articles/s41...
PIEZO2—unlike PIEZO1—is tethered to the actin cytoskeleton, enabling sensory neurons to detect localized mechanical forces such as light touch.
Findings reported in @nature.com by @ericmulhall.bsky.social from @ardemp.bskyverified.social's lab link nanometer-scale imaging to sensory function.
New work from the lab on how sickness reduces appetite. Turns out, it’s complicated :)
We focused on a single inflammatory cytokine, IL-1b, and even that reduces appetite via multiple mechanism.
Thanks to Nik Hayes for leading and sticking with this project and to everyone else who contributed!
Chuffed to see our paper with @geneyeo.bsky.social finally published in @nature.com.
www.nature.com/articles/s41...
Very grateful to Fede, Susie, and Dave from my lab, and Sammi, Eric, and Pratibha from Gene's lab. What did we find? ⬇️ ⬇️ ⬇️
New lab preprint! Can we study conscious perception of gut sensations in mice to reveal its neuronal basis? Can we train mice to report their gut sensations? Omer Rafael and Stav Shtiglitz in the lab teamed up to discover that…YES! Thread…1/6 www.biorxiv.org/content/10.6...
What if we could see 3D #biodistribution of cancer drugs at the cellular level... throughout an entire model animal? 🧐 A new paper from Li Ye's lab @scripps.edu, Zhengyuan Pang & Verina Leung et al. introduce a technique for doing just that. (1/3) 🧵
Excited to co-host this conference with @marissascavuzzo.bsky.social and Steve Liberles focused on the peripheral nervous system -- No Brainer! Check out the amazing list of speakers and apply for one of the spots for this small, interactive meeting on the beautiful Janelia Campus at HHMI.
www.nature.com/articles/s41... beautiful work from Stephen Liberles’ lab on neural mechanisms of sensing blood volume.
A very nice spinal spatial transcriptomics paper here! www.biorxiv.org/content/10.6...
Patagonia was not bad at all!
🧠⚡️💊New @nature.com publication !
Mimicking opioid analgesia in cortical pain circuits
We built a brain-behavior framework to decode spontaneous chronic pain in mice—and to biologically mimic morphine with a synthetic opioid gene therapy
nature.com/articles/s41...
@pennmedicine.bsky.social
Beautiful paper! Somebody should do it in then viscerosensory brainstem.
quote from Chen Ran: “I feel very lucky to have the support of the Simons Foundation and to have access to this outstanding community.”
Fellows-to-Faculty awardee Chen Ran maps the senses of internal organs. Receiving this award — which is currently open for apps — has been crucial in enabling his work: https://www.simonsfoundation.org/autism-and-neuroscience-innovators-awardees-share-their-research-at-the-annual-retreat/ #science
Some news. Exciting new challenges and opportunities ahead.
Thrilled this is out, led by former PD Cameron Ogg (now with her own lab at @rhodescollege.bsky.social!). It was a driven by a desire to see, in real-time, how LC activity/NE release influences downstream targets in behaving animals. SO hard to do, but Cameron did it! www.cell.com/cell-reports...
I was one of those immigrants, and we commit fewer crimes than people born here.
“Trump says he wants to “permanently pause migration” from poorer nations and is promising to seek to expel millions of immigrants from the US by revoking their legal status.”
apnews.com/article/trum...
What does it take in mechanosensory biology to earn one? Characterizing brainstem responses to stomach stretch?
Ive seen this work from Prof Liqun Luo’s presented a few times now and its stunning and heroic.
A beautiful paper on the role of Piezos in uterine biology. I have known first author Yunxiao Zhang since 2012. Yunxiao is rare talent (and a wonderfully kind human being) now on the job market!
Deeply honored to receive this year's Tianqiao and Chrissy Chen Young Investigator Award from @sfn.org Grateful to all lab members and my mentors.
Actively hiring! Video made by Sora-2 but the job post is 100% real.
Apply here: hhmi.wd1.myworkdayjobs.com/en-US/Extern...
1.5 years in the making, only two weeks to go! Can’t wait to see everyone here at Scripps!
This great primer from our #brain–body special by @dulaclab.bsky.social explores the many ways in which the brain and the immune system interact in the diseased state.
🧠
www.cell.com/current-biol...
Scripps is a wonderful place to do science. Hard to imagine better colleagues and students…
Finally out: our recent work with Nick Betley is a view into how the brain reshapes its behavior in the face of competing survival needs- and also a potential angle on treatment targets for enduring pain.
A brief rundown...
www.nature.com/articles/s41...
We’re hiring!
My new Gut–Brain Axis Lab at Northwestern is looking for a Research Technologist 2 to help build the lab and explore how the nervous system shapes gut health and disease.
🔬 Apply here: myhr.northwestern.edu/psp/hrnu/EMP...
Submedius Thalamus Modulates Orbitofrontal Cortex Representations During Maternal Behavior in Mice https://www.biorxiv.org/content/10.1101/2025.09.18.677207v1
Very interesting paper—>must read- and the first author will be looking for a job soon: one of the strongest scientists I could imagine. I learned so much from Yunxiao since my graduate school days.
