Michael Norris

A pore-forming antiphage defence is activated by oligomeric phage proteins - Nature Bacteria use diverse defence systems against phages, including a 164-residue prophage-encoded protein, Rip1, which senses conserved phage assembly rings to form membrane pores that block virion maturation and trigger premature host cell death.

Nature research paper: A pore-forming antiphage defence is activated by oligomeric phage proteins

go.nature.com/4rA3cmd

A pore-forming antiphage defence is activated by oligomeric phage proteins - Nature Bacteria use diverse defence systems against phages, including a 164-residue prophage-encoded protein, Rip1, which senses conserved phage assembly rings to form membrane pores that block virion matura...

Congratulations Pramal, @paramyxologist.bsky.social, and @themaxwelllab.bsky.social on this incredible story! Glad I got to help, even if it was just a little bit :)
www.nature.com/articles/s41...

Dear Colleagues, As part of the Canadian Cryo-EM Nexus, The Hospital for Sick Children (SickKids) and Structura Biotechnology are hosting a two-day CryoSPARC workshop at SickKids in Toronto on April 30 and May 1, 2026. Led by experts from Structura, this workshop offers a unique opportunity for participants with prior CryoSPARC experience to deepen their skills and become a key resource for cryo-EM image analysis within their institutions. Applicants should have hands-on experience with CryoSPARC, demonstrated by having processed at least two datasets, and must be committed to sharing their expertise with colleagues upon returning to their home institution. There is no charge for participating in the workshop, which is sponsored by SickKids and Structura. Attendees will need to bring their own laptop computer and arrange for travel, accommodation, and meals. Given the limited capacity (15 students), we kindly request that interested individuals ensure that they can cover these costs before registering. Please register before February 20, 2026 using the following link: https://sickkids.cventevents.com/event/a0aebb07-66e6-4cbe-b471-8009fe0c227c/summary?i=97c975e9-4bac-42b9-a1b2-95974110db9e&tm=DXVv8zGvH5uA7nqj8lEF4iifi-ukLal5QBBjdXWGD2E&locale=en-US We look forward to welcoming you to this workshop. Sincerely, Samir Benlekbir and John Rubinstein (SickKids) & CryoSPARC Team (Structura)

@structurabio.bsky.social and @sickkidsto.bsky.social CryoSPARC workshop in Toronto!
April 30/May 1st 2026.
Part of the Canadian Cryo-EM Nexus.
Please register here: sickkids.cventevents.com/event/a0aebb...

The GATE glycoprotein complex enhances human cytomegalovirus entry in endothelial cells - Nature Microbiology The gH-associated tropism and entry (GATE) complex consists of glycoprotein H, UL116 and UL141. This complex is abundant on human cytomegalovirus virions and enables entry into human endothelial cells...

🚨Out now!

The GATE glycoprotein complex enhances cytomegalovirus entry in endothelial cells.

#MicroSky🦠

www.nature.com/articles/s41...

The GATE glycoprotein complex enhances human cytomegalovirus entry in endothelial cells - Nature Microbiology The gH-associated tropism and entry (GATE) complex consists of glycoprotein H, UL116 and UL141. This complex is abundant on human cytomegalovirus virions and enables entry into human endothelial cells...

💥 Couldn’t be more stoked our study identifying a completely new CMV virion surface complex involved in cell entry is now published at Nature Micro 🦠 H/T @paramyxologist.bsky.social + Lauren Henderson, Erica Ollmann Saphire Chris Benedict @natmicrobiol.nature.com www.nature.com/articles/s41...

🚨 We’re hiring! 🚨
Exciting opportunity for a Cryo-EM Senior Research Associate at the University of Toronto!
Join a cutting-edge facility supporting groundbreaking, cross-disciplinary research. 🧬🦠🔬

📍 Toronto
🔗 jobs.utoronto.ca/job/Toronto-...

#CryoEM #ElectronMicroscopy #Hiring #UofT #AcademicJobs