What a moment — a Nobel Laureate of our own! Congratulations Mary! Truly fitting for someone who brings excellence and kindness to everything she does. 🎉🌟
10.12.2025 21:35
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What a moment — a Nobel Laureate of our own! Congratulations Mary! Truly fitting for someone who brings excellence and kindness to everything she does. 🎉🌟
The @nobelprize.org concert is one of the highlights of Nobel week! Powerful and dramatic performances in the presence of the King & the Queen. We got to meet the 2025 Physiology or Medicine Laureates: Shimon Sakaguchi, Mary Brunkow, and Fred Ramsdell (not pictured).
Mary Brunkow was generous in thanking her mentors during her The Nobel Prize lecture! Always good to look back and remember those who have made an impact in your career. She is among a long line of pre-med students who worked in a lab and fell in love with research and changed plans!
Dr. Mary Brunkow is a 2025 Nobel laureate. In today’s @isbscience.org press conference, she shares the FOXP3 story, from a puzzling mouse to a discovery that reshaped immunology.
🎥 Watch the full video: youtu.be/vg61fbycGEk
Left to right: Sean Gibbons, Naeha Subramanian, Mary Brunkow, Anna Kuchina, and Sid Venkatesh
Rubbing shoulders with a @nobelprize.bsky.social laureate! 🤩What a week!
Couldn’t have happened to a nicer person: isbscience.org/news/press-r...
@isbscience.org @naehasubramanian.bsky.social @flash-point.bsky.social @annabiosys.bsky.social
Many congratulations, Mary Brunkow! Couldn’t be happier for you and @isbscience.org ! ♥️
www.nobelprize.org
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
Excited to finally present the lab's latest work in defining candidate causal genetic variants that drive autoimmune diseases and their effects on primary human T cell expression and function! www.nature.com/articles/s41...
Pika in the wilderness of Mt. Baker. #pika #pnw #photography #wildlife
What are you up to? #birds #barredowl #pnw #Seattle #photography
Legend David Baltimore died yesterday. He understood the way things should work: "the real contribution of MIT is that it doesn't take itself too seriously. It takes ideas seriously, but the people are relatively informal. They are not self-aggrandizing the way academics can be."
Please read this wonderful article about my fabulous partner in life, Dr Jennifer Quinn and her work at the Seattle Math Museum! Spread the mathematical joy! @jennifer.j.quinn
www.geekwire.com/2025/seattle...
Postdoc position (please re-post)
A funded postdoctoral position, will open in 2026 to study aspects of Neisseria gonorrhoeae pathogenesis, antigenic variation, genetics, or physiology.
If interested in more information, please contact Hank Seifert
h-seifert@northwestern.edu
#MicroSky
We're hiring! Our lab @ISB is looking for a full-time Research Associate to manage our mouse colony 🐭, run experiments in a Type 1 diabetes model, and help keep the lab running smoothly.
Ideal for someone aiming for grad school or further scientific training. isbscience.bamboohr.com/careers/56
My heart. Members of the US Public Health Service (the uniformed service branch no one has ever heard of, who serve at the CDC and elsewhere in the US), massed within the CDC property, saluting their departing uniformed leaders who were escorted out by security today after resigning on principle.
CDC staff held a “clap-out” on Thursday to honor three of the agency’s high-ranking officials, who resigned in protest after President Trump fired the director, Susan Monarez. nyti.ms/4oSxakJ
Abbe Lowell and I represent CDC Director #SusanMonarez. Contrary to govt statements, Dr. Monarez has neither resigned nor yet been fired. She will not resign. We have issued the following statement:
“Putin would eat you for lunch.”
Today, exactly that happened.
Let's please keep the remaining staff at NIH, NSF, etc in our thoughts even as you lose sleep over your own lab and scientific career.
They are enduring pure chaos to try to hold the fort.
See snapshot from wapo.st/4feKKuu (gift 🔗) saying they are "barely holding it together"
Shout out to the WSJ journalists who reported on Vought’s impoundment by footnote, causing the White House to walk it back. Impact journalism!!
Now up, led by Ashton Omdahl! Our method GLEANR finds shared genetic factors across lots of GWAS, and handles spurious correlation driven by cohort overlap. Neat examples of factors driving related traits with enrichment in different cell types / developmental stages.
The NIH was healthiest when pay lines were in the 20th percentile range.
We are headed into an environment where pay lines are in the 5% range.
In my entire career, I’ve only had 3 grants that scored better than 5%. And my lab is considered a successful one.
This is going to destroy science.
When we held our rally after the roundtable on Monday to support the #NIH science, we invited Jay Bhattacharya to join us.
He declined saying he was disappointed we “made it political.”
But supporting NIH isn’t partisan! www.politico.com/news/2025/07...
Evolutionary molecular biology paying dividends again - this time in finding new modulators of innate immunity - www.science.org/doi/10.1126/...
Happy Birthday, Rosalind Franklin. She captured an X-ray diffraction image of DNA and stated that a helical structure was probable. Watson and Crick then created a detailed model based on her results. They initially received credit for the discovery and were awarded the Nobel Prize after her death.🧪
Another Bhattacharya email today
1/4
Abughazaleh: I am from one of those families. I do not want Israeli children to live in fear. And I don't want gazan children to starve to death. And there is no enemy of either state that could want me to wish that or excuse the starvation of children. It is that simple.
Are you an excellent researcher in the field of genomics of infectious diseases of intracellular pathogens (viruses, intracellular parasites or bacteria)? The apply for this chair of excellence at the University of Geneva, Faculty of Medicine:
jobs.unige.ch/www/wd_porta...
Each Friday, I write a summary of what happened this week in science 🧪& higher ed:
- EPA shutting down office of research
- NIH selecting politically-preferred reviewers
- ICE surveillance tech
- unsnarling research funding news
This was Week 26, a marathon.
buttondown.com/liminalcreat...
