Andy Radde-Gallwitz ❌👑

Actually nvm I like the ignorance on whatever this discourse is

What on earth is everyone talking about?

Same

(In the sense of “atheism” as pejorative, as in Emerson’s “To wish for war is atheism.”)

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Aaron Rupar @atrupar X.com Trump notes his crowd is more enthused about bigotry than they are for tax cuts: "It's amazing how strongly people feel about that. I talk about cutting taxes, people go like that, I talk about transgender everybody goes crazy. Five years ago you didn't know what the hell it was" LIVE GREENSBORO, NC cc # 45 our Children. 5:45 PT LIVE BREAKING NEWS TRUMP SPEAKS IN NORTH CAROLINA 'UNABOMBER' TED KACZYNSKI, 81, FOUND DEAD IN PRISON. GO TO NEWS 5:49 PM • 6/10/23 • 14M Views

George Wallace in 1962: "I started off talking about schools and highways and prisons and taxes and I couldn't make them listen. Then I began talking about n**rs and they stomped the floor."

Donald Trump in 2023⬇️

It’s giving middle passage

Ok I have an #NEISvoid hot take:

I agree we have too many Long Covid observational studies BUT I think we need to push for investment in pathobiology research more than trials.

Identifying disease mechanisms can produce treatment targets to direct trials, instead of throwing spaghetti at the wall.

Thanks! And yikes! (I’ve actually seen this done to sheep.)

Classicists: ancient Greek didn’t use the metaphor of “pressing” (as in θλίβω) for what we call “expression”? That’s a Latin invention (as in exprimo and derivatives)?

OSA is part of my Long Covid.

New fallacy just dropped: the False Herring.

When you distract an opponent with a fish story.

Or

When you, an unfaithful herring, distract an opponent.

The scholarly article: Gosh, there’s a lot to say on this topic and I’m unfortunately not going to be able to get around to any of it

20 years. Mon dieu you are strong.

The constant, unanswerable question

3) Low-Dose Sirolimus (Rapamycin) for Long COVID
clinicaltrials.gov/study/NCT069...

4) NE3107 for Long COVID
clinicaltrials.gov/study/NCT068...

5) Tafenoquine for Babesiosis with Severe Fatigue
clinicaltrials.gov/study/NCT066...

1) Lumbrokinase for LC, ME/CFS, Post-Treatment Lyme Disease
clinicaltrials.gov/study/NCT065...

2) Antivirals for Long COVID
Trial will test if two repurposed HIV antivirals can reduce symptom burden in adult participants with Long Covid compared to placebo.
clinicaltrials.gov/study/NCT065...

Over on threads someone just use ai;dr and we all need to adopt that right quick

🫂 to you both

I feel I’m watching one of the events of Super Bowl history

And I still wouldn’t trust a Running Back named Walker

Sam is Darn Old

Not a single thing we were told about #COVID turned out to be correct. A long thread 🧵

“We report ROI-to-ROI functional connectivity differences between the cortical and subcortical brain regions in
pwLC, pwME/CFS and HC using baseline and repeat 7T task fMRI. We found regional connectivity to be
significantly disparate between patient and healthy cohorts secondary to cognitive .. “

Distinct functional connectivity patterns in myalgic encephalomyelitis and long COVID patients during cognitive fatigue: a 7 Tesla task-fMRI study - Journal of Translational Medicine Journal of Translational Medicine - Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and long COVID are chronic debilitating illnesses featuring fatigue, post-exertional malaise (PEM)...

Has this study made the rounds of Bluesky #ME/CFS and #LongCovid #pwLC #pwME?

“… FC differences in ME/CFS and long COVID patients indicated reduced and dysregulated regional coordination that may serve as candidate biomarkers of symptomatology in long COVID and ME/CFS.”

And ya know the last shall be first

Nature Immunology: Long COVID involves activation of proinflammatory and immune exhaustion pathways ABSTRACT Long COVID (LC) involves a spectrum of chronic symptoms after acute severe acute respiratory syndrome coronavirus 2 infection. Current hypotheses for the pathogenesis of LC include persistent virus, tissue damage, autoimmunity, endocrine insuf...

Nature Immunology: Long COVID involves activation of proinflammatory and immune exhaustion pathways #ThatCovidLife #CovidIsNotOver

Same!

“Reinfection was associated with more than double the risk of a long COVID diagnosis” in a large study of children and adolescents.

long covid often presents as mecfs or similarly, which patient surveys have indicated carries a poorer quality of life than literally every type of cancer. it’s decimated my quality of life since contracting it in late 2022. exposing children to that fate for your own comfort is unconscionable