Excited to share our work published in @cp-immunity.bsky.social! We investigated the role of HIF-1α in CD4 T cells using #Xenium spatial transcriptomics in infected lungs containing #TertiaryLymphoidStructures (TLS) (1/10).
www.cell.com/immunity/ful...
Delighted to share our latest paper, led by Dr Ximena Raffo-Iraolagoitia, just published in Science Advances! www.science.org/doi/10.1126/...
Colonic Engyodontium fungus triggers neutrophil antimicrobial activity to suppress Lactobacillus johnsonii-derived glutamic acid-maintained Tregs
www.jci.org/articles/vie...
@jci.org
Lymph nodes, can’t remember what the red stained for…
Impressive… My hands often shake badly whenever I try to take pictures from the eyepiece, usually had to take several pics in a row just to get one good picture with perfect angle…
📣Register now for the Beatson International Cancer Conference 2026 ‘From Tumour Genesis to Metastasis: an immune perspective’
📅22-25 June 2026
📍CRUK Scotland Institute, Glasgow
🎟️Early Bird registration closes on 1 April
🔗 www.beatsonconference.org
#BICC2026 #CancerResearch #Immunology
Our latest review is out, a comprehensive synthesis of #tissue #Tregs. It has been a decade since @annualreviews.bsky.social #immunology last reviewed #TissueTregs, and there have been enormous advances and conceptual leaps forward in the field
www.annualreviews.org/content/jour...
A data figure showing a phylogenetic tree of H3N2 with 2025-K highlighted, the structure of the HA trimer with mutations characteristic of K highlighted, and box and whisker plots showing % neutralisation of the 2022 H3N2 vaccine strain, and of 2025 clade K, by various human antisera
🚨New Pre-Print🚨
Although H3N2 subclade K has multiple mutations in HA, neutralisation assays with pre-epidemic human sera show only moderate antigenic drift, and vaccines used in the 2024/2025 flu season induced cross-neutralising immunity
www.medrxiv.org/content/10.6...
Our new book "Self-Doubt" is written by scientists for scientists. You might think you are alone when you doubt your ability or suitability for science - you aren't. We all question ourselves and carry doubt with us daily.
www.amazon.co.uk/Self-Doubt-A...
Just out @natrevimmunol.nature.com
RNA-binding proteins and ribonucleoproteins as determinants of immunity
www.nature.com/articles/s41...
gives our perspective on this growing area of research. Special thanks to the editor Alexandra, for streamlining the manuscript.
🚨 Deadline approaching! Last chance to present your work at #SIGNET26.
Abstract submissions close this Thursday, 29 January, with oral presentation slots reserved for postdocs and PhD students, plus poster prizes.
🔗 https://bit.ly/49VL6FA
Quite like the “watermark” in the cell membrane, should make these into a calendar… I’d definitely pick up a few.
We are delighted to announce that @mitosrus.bsky.social from @cruk-si.bsky.social @glasgow.ac.uk has been awarded the 2026 Hooke Medal
You can read about Stephen's work on mitochondria, cell death and cancer here:
bscb.org/hooke-medal-...
Finally, my PhD project is published! 🎉
I am thankful to all the collaborators who made this possible!
www.nature.com/articles/s41...
@natcomms.nature.com
#dendriticcells #immunesynapse #centrosome
🤯
New research news! Supercharging immune cells could provide an effective way to tackle cancer #CancerResearch www.gla.ac.uk/news/headlin...
An atypical low stiffness epithelial-to-mesenchymal transition state that prevents immune cell-mediated killing of dormant metastatic lung adenocarcinoma
@natcancer.nature.com @mskcancercenter.bsky.social
www.nature.com/articles/s43...
www.nature.com/articles/s43... @cedric-blanpain.bsky.social
🚀 Our new Publication in Nature Biomedical Engineering!🎉
📄 Title: Generation of T cells with reduced off-target cross-reactivities by engineering co-signalling receptors
🔗 Read the full paper here: www.nature.com/articles/s41...
Happy new year!!
'The presence of CD8+ T cells coexpressing residency and exhaustion molecules in chronic diseases often correlate with clinical outcomes; however, the relationship between these cells and conventional tissue-resident memory (TRM) cells or exhausted CD8+ T (TEX) cells is unclear.'
#Immunology
👇See our newest study:
What was supposed to be a control experiment uncovered a new function of mTOR: 3’mediated translation control in primary human T cells, mediated through DDX21. AU-rich elements are required for this effect. Happy reading!
authors.elsevier.com/a/1mDFf3vVUP...
Cytochrome c oxidase dependent respiration is essential for T cell activation, proliferation and memory formation @natcomms.nature.com
www.nature.com/articles/s41...
How can we optimize the delivery of IL-2 to traumatic brain injury patients?
www.tandfonline.com/doi/10.1080/...
Neat🤯 can’t imagine how long the processing took for these…
The methyl-CpG-binding protein 2 inhibits cGAS-associated signaling @natcomms.nature.com
www.nature.com/articles/s41...
We are delighted to announce the Strathclyde Optical Microscopy Course 2026 (SOMC26), taking place in Glasgow from 21st July – 30th July 2026!
Please find more details at shorturl.at/xmUiZ and apply at shorturl.at/MxTlI. Deadline 16 January 2026.
A small 🧵 encouraging people to publish protocols.
Our #AutoSpectral release has made me reflect on how much the community tends to appreciate protocol papers. People rarely present protocols as their main achievements, but they are often the most impactful work.
www.biorxiv.org/content/10.1...
Shouting didn’t help, threw mine out the window and the problem went away :)
Joke aside apparently there’s a bug with keyboard input with iPhones recently…
Preview @cp-immunity.bsky.social
Burning the candle at both ends: ROS-mediated telomere damage drives T cell dysfunction
www.cell.com/immunity/ful...
on
www.cell.com/immunity/ful...
When you had quals & published your first paper!✨behind✨SO PROUD to share we published our first piece of the CasL story!! journals.biologists.com/jcs/article/... The scaffold protein CasL restrains membrane blebbing and promotes T cell migration | Journal of Cell Science | The Company of Biologists
An age-related decrease in leptin contributes to CD8+ T cell aging in the tumor microenvironment @cp-cellrepmed.bsky.social
www.cell.com/cell-reports...
