Rich Compton

Exciting preprint from Haoyu Cheng (not on bluesky?) and @lh3lh3.bsky.social: building amazing Nanopore assemblies just got faster and more accessible! Thrilled to have played a small part in this work!

This new Hifiasm --ont option is amazing. It worked like a charm for us in the nanopore adaptive sampling based assembly paradigm we introduced in a preprint recently.

www.biorxiv.org/content/10.1...

Efficient near telomere-to-telomere assembly of Nanopore Simplex reads Telomere-to-telomere (T2T) assembly is the ultimate goal for de novo genome assembly. Existing algorithms capable of near T2T assembly all require Oxford Nanopore Technologies (ONT) ultra-long reads w...

Preprint on hifiasm Nanopore-only assembly. Led by Haoyu Cheng: www.biorxiv.org/content/10.1...

Efficient near telomere-to-telomere assembly of Nanopore Simplex reads (hifiasm) www.biorxiv.org/content/10.1... 🧬🖥️🧪 github.com/chhylp123/hi...

Telomere-to-telomere phased genome assembly using error-corrected Simplex nanopore reads https://www.biorxiv.org/content/10.1101/2024.05.18.594796v1 Telomere-to-telomere phased assemblies are standard expectations. To achieve these for diploid and e

Telomere-to-telomere phased genome assembly using error-corrected Simplex nanopore reads https://www.biorxiv.org/content/10.1101/2024.05.18.594796v1

My first post on this platform is dedicated to the Women in STEM event at #AGBT2025. Hope to meet many of you there!

3️⃣ Women’s Networking Event (Feb 24):
Join us as we celebrate women in science and support the next generation of researchers. Attendees can vote for one of three inspiring projects to receive a bursary for future conference presentations.

We're expanding our collaboration with @10xgenomics.bsky.social to enable seamless compatibility between their latest GEM-X chemistry, bringing more accurate, cost-effective, and accessible insights to #singlecell and spatial #transcriptomics research.

Learn more: nanoporetech.com/news/oxford-...

Stop by the @nanoporetech.com Lanai suite #190 at #AGBT2025 #AGBTGM tonight after the welcome reception. We’re open from 7pm.

We can’t wait to PORE you a beverage. 😂

Talk by
@khmiga.bsky.social for the @sinaigenhealth.bsky.social Institute for Genomic Health Seminar Series on the potential of complete genomes and pangenomes for improving human health

Some thoughts about what I am looking forward this year from my vantage point of computational molecular biology. One mega-trend for me; we will definitely see more AI methods of all sorts emerge.

So long San Diego! Here’s my opinionated meeting report from #PAG2025 | #PAG32. What else did I miss???

HERRO was one of the heroes from #PAG2025 | #PAG32

All the talk of 🐮 reminds me we need to get that Braunvieh T2T assembly done together!

Let me know if you want to be added to the Genomics Technology starter pack go.bsky.app/3oiGMBe

Apparently, I am Mr. August for a patent of a protocol for #nanopore simultaneous sequencing of long and short RNAs
https://buff.ly/3OK2iSx
#UNM

Landmark genetics partnership to probe causes of cancer and dementia Oxford Nanopore’s breakthrough genetic sequencing tech to analyse 50,000 samples from UK Biobank, to create a world-first ‘epigenetic map’.

Exciting! - epigenetic markers may enable cost effective diagnosis of disease, disease progression and drug response. Imagine combining genetic markers of disease risk with epigenetic markers to create the clinical tools that support prediction, prevention & outcomes

www.gov.uk/government/n...

Oxford Nanopore Houston NCM Tech update Oxford Nanopore gave an update in the US NCM meeting, which took place in Houston Texas, with some Work In Progress (WIP) on new developments in terms of chemistry, motors and software. Motor/Res cond...

Oxford Nanopore Houston NCM Tech update open.substack.com/pub/albertvi...