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Paul Anastasiades

@panastasiades

Neuroscientist at University of Bristol. Cortical circuits, PFC, interneurons, dopamine, brain development. https://www.anastasiades-lab.org

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29.08.2023
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Latest posts by Paul Anastasiades @panastasiades

If you're at #cosyne2026 and want to discuss opportunities in our group below let me know! 2x Postdoc, research assistant and PhD possibilities, based at University of Oxford or Trinity College Dublin.

13.03.2026 12:32 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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⏰ Final call for IBRO Collaborative Research Grants! Applications close in 2 days, 15 March

Make sure to finalize your proposal & submit on time!
ow.ly/Ihxg50Yseyt

@danek8317.bsky.social @apmsilva.bsky.social @eazim.bsky.social

13.03.2026 09:25 πŸ‘ 0 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Applications are open for our Next Generation Leaders program!

Our NGL program recognizes emerging scientific leaders and invites them into a supportive network.

πŸ”— Apply by March 31: https://alleninstitute.org/about/people/next-generation-leaders/

12.03.2026 19:06 πŸ‘ 8 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0

OK If we are moving to Bluesky I am rescuing my favourite ever twitter thread (Jan 2019).

The renamed:

Bluesky-sized history of neuroscience (biased by my interests)

01.12.2024 20:29 πŸ‘ 631 πŸ” 205 πŸ’¬ 14 πŸ“Œ 14

If you work at the intersection of computational neuroscience and machine learning, consider applying for this postdoc position (January 2027 start date):
academicpositions.harvard.edu/postings/15868
An opportunity to work with a great group of people across Harvard, MIT, and UC Berkeley.

10.02.2026 19:36 πŸ‘ 75 πŸ” 50 πŸ’¬ 3 πŸ“Œ 2

Digital Twin Brain simulation and manipulation of a functional brain network underlying mental illness https://www.biorxiv.org/content/10.64898/2026.03.06.710030v1

10.03.2026 11:15 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
A functional influence based circuit motif that constrains the set of plausible algorithms of cortical function There are several plausible algorithms for cortical function that are specific enough to make testable predictions of the interactions between functionally identified cell types. Many of these algorithms are based on some variant of predictive processing. Here we set out to experimentally distinguish between two such predictive processing variants. A central point of variability between them lies in the proposed vertical communication between layer 2/3 and layer 5, which stems from the diverging assumptions about the computational role of layer 5. One assumes a hierarchically organized architecture and proposes that, within a given node of the network, layer 5 conveys unexplained bottom-up input to prediction error neurons of layer 2/3. The other proposes a non-hierarchical architecture in which internal representation neurons of layer 5 provide predictions for the local prediction error neurons of layer 2/3. We show that the functional influence of layer 2/3 cell types on layer 5 is incompatible with the hierarchical variant, while the functional influence of layer 5 cell types on prediction error neurons of layer 2/3 is incompatible with the non-hierarchical variant. Given these data, we can constrain the space of plausible algorithms of cortical function. We propose a model for cortical function based on a combination of a joint embedding predictive architecture (JEPA) and predictive processing that makes experimentally testable predictions. ### Competing Interest Statement The authors have declared no competing interest. Swiss National Science Foundation, https://ror.org/00yjd3n13 Novartis Foundation, https://ror.org/04f9t1x17 European Research Council, https://ror.org/0472cxd90, 865617

Our work with @georgkeller.bsky.social on testing predictive processing (PP) models in cortex is out on biorvix now! www.biorxiv.org/content/10.6... A short thread on our findings and thoughts on where we should move on from PP below.

30.01.2026 14:37 πŸ‘ 47 πŸ” 16 πŸ’¬ 2 πŸ“Œ 1
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Assistant or Associate Professor (Research and Education) - School of Biosciences - 107106 - Grade 8 or 9 Evidence of a developing track record in publishing work of high academic quality and impact is essential, as is an emerging portfolio (or clear potential) of external research funding. Applicants mus...

The School of Biosciences @unibirmingham.bsky.social is recruiting five Assistant/Associate Professors working across a range of areas, including neuroscience.

Join a vibrant interdisciplinary research environment.

Deadline: 14 April 2026

edzz.fa.em3.oraclecloud.com/hcmUI/Candid...

09.03.2026 16:22 πŸ‘ 14 πŸ” 22 πŸ’¬ 1 πŸ“Œ 0
Crude oil prices, showing a very sharp increase in the last day, from around 65 to 101 dollars per barrel..

Crude oil prices, showing a very sharp increase in the last day, from around 65 to 101 dollars per barrel..

Oil prices wouldn't be all over the news today if more of our economy was powered by local, secure renewable energy.

This isn't an "energy crisis". It's a fossil fuel crisis.

44% of UK electricity came from renewables in 2025. More of that plus an electrified economy => no more oil shocks.

09.03.2026 10:15 πŸ‘ 3002 πŸ” 878 πŸ’¬ 88 πŸ“Œ 53

Urgh

08.03.2026 09:08 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Happy to share our new study about how cortical and thalamic inputs engage cholinergic interneurons in the nucleus accumbens (NAc) core, all done by my graduate student Emily Jang:
www.biorxiv.org/content/10.6...

07.03.2026 21:40 πŸ‘ 12 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

We’re excited that the @fens.org Forum 2028 is coming to #Glasgow, with the BNA as host society. We look forward to welcoming neuroscientists from across Europe and beyond to Scotland.

Neuroscience, collaboration, and a Glasgow welcome - and yes, the ceilidh shoes may be required!

06.03.2026 15:50 πŸ‘ 3 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

Oh, neat. Good thing we're having to deal with complete global fucking chaos because of one insane narcissistic pedo man-baby instead...

06.03.2026 17:15 πŸ‘ 11 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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DOPAMINE 2026 Room Sharing Interested in finding fellow delegates to share hotel rooms with during Dopamine 2026? If so, please fill out the form below! Once you complete your information, you will be sent an email with inform...

🚨DOPAMINE2026 (Sevilla, Spain)

Looking for someone to share a room with?
Here’s the room-share formπŸ‘‡πŸ»

docs.google.com/forms/d/e/1F...

08.12.2025 18:40 πŸ‘ 5 πŸ” 5 πŸ’¬ 0 πŸ“Œ 1
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A sickening society is clear in these statistics

So why is it not in the news?

Powerful wake-up call from @chakrabortty.bsky.social www.theguardian.com/commentisfre...

06.03.2026 08:24 πŸ‘ 173 πŸ” 123 πŸ’¬ 14 πŸ“Œ 19

Postdoc position in affective neuroscience and computational psychiatry at the Donders Centre for Cognitive Neuroimaging

04.03.2026 14:45 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Orbitofrontal cortex drives predictive filtering of sensory responses - Nature Neuroscience Top-down projections from the orbitofrontal cortex carry predictive signals that grow with sound experience and suppress the auditory cortex via inhibitory circuits, revealing a predictive mechanism f...

Orbitofrontal cortex drives predictive filtering of sensory responses

www.nature.com/articles/s41...

#neuroskyence

02.03.2026 15:41 πŸ‘ 75 πŸ” 28 πŸ’¬ 0 πŸ“Œ 2
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How Imprinted Genes Shape Nurturing Behaviours and Neural Circuits Abstract. Genomic imprinting is an epigenetic phenomenon that, in animals, is found only in placental mammals and, to a lesser extent, marsupials. Broadly, differential epigenetic marking of the genom...

New review article from my lab!
🧬🧠🐭

karger.com/bbe/article/...

02.03.2026 13:42 πŸ‘ 8 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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We think of white matter as the highways of the brain. But when we followed development along those highways, we were surprised. The journey is more complex than we thought. My final PhD paper, β€œTwo Axes of White Matter Development”, is now out in @natcomms.nature.com! πŸ›£οΈπŸ§ βœ¨
πŸ”— bit.ly/wm2axes

02.03.2026 01:09 πŸ‘ 103 πŸ” 47 πŸ’¬ 2 πŸ“Œ 4

Nav1.8 mediates peripheral-to-central nociceptive transmission independently of central presynaptic mechanisms in human DRG-spinal cord circuits https://www.biorxiv.org/content/10.64898/2026.02.27.708640v1

01.03.2026 07:15 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Lecturer jobs at Bristol -one week to go! Anyone is welcome to apply, but we definitely need some more female colleagues! Please don't hesitate to contact me to chat about how it is to work at our school 😊

27.02.2026 18:35 πŸ‘ 6 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
JOIN US | IrrationalityLab

πŸ”Ž The search is broadening -- and sharpening πŸ”Ž

πŸš€We continue to look for people interested in helping build something unique at the intersection of computational, behavioural, and neural sciences at @tcddublin.bsky.social
#neurojobs #neuroscience #compneuro
www.ktsetsoslab.net/join-us

27.02.2026 17:40 πŸ‘ 4 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Could you help shape the next generation of neuroscientists? 🌟

The BNA Scholars Programme is seeking mentors to support early-career researchers from underrepresented backgrounds.

Learn more & apply:
www.bna.org.uk/policy-advoc...

#Neuroscience #Mentorship #DiversityInScience

27.02.2026 17:02 πŸ‘ 2 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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Brain Growth Patterns Predict 2-Year Neurodevelopment bioengineer.org/brain-growth...
Growth of fetal brain with long-term neurodevelopmental validation provides insights into in utero brain maturation and their predictive relationship with postnatal neurological function. doi.org/10.1038/s414...

26.02.2026 14:48 πŸ‘ 5 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
038934 - Htr2a-EGFP-CT-IRES-CreERT2 , Htr2a[EGFP-CreERT2] Strain Details

For those who study #psychedelics --our 2A mice are now available at JAX
038934 Htr2a EGFP-CreERT2 www.jax.org/strain/038934

038935 Htr2a Cre 5 www.jax.org/strain/038935

038936 Htr2a A242S-EGFP-Cre www.jax.org/strain/038936

Please RT

26.02.2026 19:07 πŸ‘ 8 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

Are you a computational postdoc or even in the last year of your PhD and you want to set up your own lab? Want to work in one of the most multi-disciplinary and multi-national institutions in the world? Want to be a leader in understanding biology - molecules up? Apply below!

26.02.2026 19:10 πŸ‘ 25 πŸ” 26 πŸ’¬ 1 πŸ“Œ 1
A view of the steel sculpture and shadow silhouettes of The Midnight ballet by Will Budgett

A view of the steel sculpture and shadow silhouettes of The Midnight ballet by Will Budgett

Tomorrow the talented young dancers of the Bristol Russian Ballet School will be joining us is Royal Fort Gardens for a special pop up demo, inspired by the Midnight Ballet. No need to book, just come along from approximately 6.30pm.
bristollightfestival.org/events/6355-2/

26.02.2026 15:44 πŸ‘ 6 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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The Journal of Neuroscience: 46 (8)

Very excited to share a Special Collection at the Journal of Neuroscience (@sfnjournals.bsky.social) - Central Questions for Social Neuroscience Research. This issue includes some of the latest perspectives on social neuroscience research. Please check it out!πŸ‘‡

www.jneurosci.org/content/46/8

25.02.2026 21:52 πŸ‘ 27 πŸ” 16 πŸ’¬ 0 πŸ“Œ 0
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🌟 Applications are open for the 'Transatlantic Behavioural #Neuroscience School 2026' organised by Nencki Open Lab!

πŸ“ MikoΕ‚ajki, Poland
πŸ—“οΈ 11–22 August 2026

Good news: #FENS #TravelGrants and fee waivers are available! πŸ’Ά
πŸ‘‰ Apply by 15 March 2026: buff.ly/yF1T7r5

25.02.2026 13:01 πŸ‘ 2 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0