@akanksha-jain
Ass. Prof. Of Neural MorphoGenomics @DMLS, Uni Zurich. •4D tissue morphogenesis •Human organoids •Developmental biology •Evolution of tissue mechanics. Previous @ETH @mpicbg @DBS-TIFR https://akankshajain2022.github.io/AkankshaJain.github.io/
And here is the link to access the whole pdf. Enjoy!
I strongly believe that focusing on information & computation during Development provides an important framework, that encapsulates the genetic, chemistry & mechanics, but focusses on organisation, dynamics & logic.
PDF: tinyurl.com/4hn34t8w
1/ 🚀🧪🤖 Big update for #Omega — the LLM-powered autonomous agent for bioimage analysis in @napari.org ! Custom LLM endpoints, layer actions, plugin extensibility, agentic widget maker, modernized UI, & 30+ fixes. Here's what's new in version *2026.2.8.2*:
In @elife.bsky.social: A high-resolution, easy-to-build light-sheet microscope for subcellular imaging doi.org/10.7554/eLif...
Checkout this updated preprint-a tour de force and truly globe-spanning collaboration with an exceptional group of scientists.
NEXT TUE: DDD seminar, Jan. 27, 2025 @ 1PM Eastern US: Nadezhda Azbukina @nazbukina.bsky.social (from Dr. Barbara Treutlein's group) will speak on "A systematic study of morphogen patterning and its reproducibility in human neural organoids". carlocolantuoni.org/seminar
Open-source atlas of fruit fly development DynamicAtlas is a high-res framework for morphological studies
📹 M. F. Lefebvre, V. Jain-Sharma, N. Claussen & N. P. Mitchell et al @streichan.bsky.social lab University of California Santa Barbara in @natmethods.nature.com
➡️ bpod.org.uk/archive/2026...
📣Registration deadline approaching !📣
Check out @embo.org @biologists.bsky.social workshop "biophysical & molecular mechanisms of animal homeostasis & repair" 6-10th April, with a fantastic lineup of speakers! meetings.embo.org/event/26-hom....
Register/Abstract submission by 10th January.
Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩
@poldresden.bsky.social @mpi-cbg.de
In @natphys.nature.com, they demonstrated that the zebrafish embryo “reads” and correctly interprets the zygote’s geometry during the initial few minutes of its existence. They discovered ...
📷 C.-P.Heisenberg, N. Mishra, Y. I. Li (from left to right).
Brain Surfaces of 70 primate species
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To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, you’ll be surprised!
🧵Thread on our new preprint with @r3rt0.bsky.social , doi.org/10.1101/2025...
I am extremely happy to see this work online! Long discussions about which, when and how much of morphogens or combinations result in what neural cell type/brain patterning culminated in this wonderful story, powered by multiplexed single-cell RNAseq. Follow the thread for a concise intro 🎊📣
Mastodon: the Command Center for Large-Scale Lineage-Tracing Microscopy Datasets https://www.biorxiv.org/content/10.64898/2025.12.10.693416v1
We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji.
It ships many new features, detailed below, but that are articulated around the following:
Some ideas and discussions from our recent Asilomar meeting on the ethics and societal implications of neural organoid and assembloid research
www.the-scientist.com/as-neural-or...
Background of DNA strand with logos of King's College London and the Leverhulme Trust and text Coping with mechanical stress: tissue dynamics during development, homeostasis and repair Professor Yanlan Mao University College London Force Talks Mechanics of Life Leverhulme DSP seminar series
Our next #ForceTalk is Prof Yanlan Mao @yanlanmao.bsky.social on "Coping with mechanical stress: tissue dynamics during development, homeostasis and repair"
🗓️ 26 Nov 2025
🕒 15:00 - 16:00 GMT
Online & open to all 👉 www.kcl.ac.uk/events/force-talk-yanlan-mao
#mechanobiology @kingsnmes.bsky.social
NEXT TUE: DDD seminar, Nov. 18, 2025 @ 1PM Eastern US: Continuing our focus on approaches to the study of many pluripotent stem cell lines, Dr. Michael Wells @mfwells.bsky.social will share his recent work on "cell villages". seminar info: carlocolantuoni.org/seminar [repost to spread the word]
Congratulations! Very beautiful cover and paper 🤩
Best sign off ever ! 😂
🧠 Join us @uzh-ch.bsky.social ! We are a new lab looking for PhDs, Postdocs & Master’s students interested in studying how human neural systems emerge & go awry using brain organoids, light-sheet imaging & genomics. 🚀 Deadline for LSZGS 1st Nov! www.lifescience-graduateschool.uzh.ch/en.html.
If you’re applying to your dream lab for an internship/PhD/postdoc, always send a second email 1-2 weeks after the first one if you don’t hear back.
I promise we will be grateful rather than annoyed. My email inbox is a disaster and I’m quite junior - and very few of us have secretarial support
Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd
Ever wondered how robust cellular identity is to external perturbations? Here we disrupt cellular environmnent in vivo and in vitro, and find cell population specific sensitivities. Environment sculpts development yes, but not all cells are made of the same wood. www.science.org/doi/10.1126/...
This is absolutely a must read. We are in deep trouble and I am even less optimistic than the authors.
Another #preprint: "Elasticity and plasticity of epithelial gap closure", from the #PhD work of Maryam Setoudeh:
arxiv.org/abs/2509.05110
This one required a lot of (I think) beautiful #mechanics!
@mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
Our work is motivated by Tribolium serosa closure, a particularly simple instance of epithelial gap closure:
nature.com/articles/s41467-020-19356-x
@akanksha-jain.bsky.social @paveltomancak.bsky.social discovered tissue fluidisation near the gap and inhomogeneities of the contracting cable.
Join us on November 4th!
The winners of our best short talk awards will be telling their research on the @isscr.org stage!
Thank you @stemcellreports.bsky.social for co-organizing this webinar!
Super excited that our group will be supported by an ERC Starting Grant!
In project "InfoFate" we will study how cells use information in dynamical, neighborhood & mechanical signals to make decisions.
We'll have PhD and Postdoc positions available, please get in touch if interested!
Congratulations!!!! Big and awesome news ! Hugs 🤗🎊🎊🎊🎊
Congratulations!!! Great day of news 🎊🎊🎊🎊
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
