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Muskan Gupta

@muskang

Doctoral Researcher at MPI-IE (Flury Lab) She/Her

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15.12.2024
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Latest posts by Muskan Gupta @muskang

Read in Nature: nature.com/articles/s41586-025-09899-8

Read in Nature: nature.com/articles/s41586-025-09899-8

Stress controls epigenetic inheritance!

A histone ubiquitylation-based regulatory hub links stress/environmental signaling to heterochromatin self-propagation and epigenetic inheritance-reshaping how we think about development, drug resistance, and cancer
👉 nature.com/articles/s41586-025-09899-8

07.01.2026 16:46 👍 35 🔁 22 💬 3 📌 4

Our latest collaboration with the talented Susi @sbantele.bsky.social and Jiri Lukas is out now @science.org 🤩. We reveal the hidden price for DNA repair, with potential implications for genome function, gene therapy and ageing👇

07.11.2025 08:34 👍 43 🔁 16 💬 0 📌 1
Poster for Career Evening 2026 with the motto “Looking Beyond Academia” and a list of speakers from various scientific and industrial fields, event date, time, and location, as well as a QR code for registration.

Date: 09.02.2026 & 17:00 c.t. - 20:00
University of Freiburg, Physiology lecture hall
Host: IMPRS & SGBM

Kontakt: imprs@ie-freiburg.mpg.de

Speaker line-up
 
Dr Nikki van Teijlingen Bakker
Global Strategy Manager, Olympus Corporation

Dr Esen Dogan
Senior Manufacturing Process Expert, WuXi Biologics

Dr Lukas Denkhaus
Trainee Patent Attorney, Maucher Jenkins

Dr Monika Puchalska
Scientific Consultant, Biognosys

Dr Ralph Dahm
Scientific Management Director, Institute of Molecular Biology

Dr Marc Bayer
Scientist, BioNTech

Poster for Career Evening 2026 with the motto “Looking Beyond Academia” and a list of speakers from various scientific and industrial fields, event date, time, and location, as well as a QR code for registration. Date: 09.02.2026 & 17:00 c.t. - 20:00 University of Freiburg, Physiology lecture hall Host: IMPRS & SGBM Kontakt: imprs@ie-freiburg.mpg.de Speaker line-up Dr Nikki van Teijlingen Bakker Global Strategy Manager, Olympus Corporation Dr Esen Dogan Senior Manufacturing Process Expert, WuXi Biologics Dr Lukas Denkhaus Trainee Patent Attorney, Maucher Jenkins Dr Monika Puchalska Scientific Consultant, Biognosys Dr Ralph Dahm Scientific Management Director, Institute of Molecular Biology Dr Marc Bayer Scientist, BioNTech

“Looking Beyond Academia” | Feb 9 | @uni-freiburg.de

One of the most nerve-wracking questions for PhD students: What comes after the doctorate? To ease the transition into the next career phase, we invite you to join the IMPRS @sgbmfreiburg.bsky.social #Career Evening.

Register: s.gwdg.de/yjlAXo

15.01.2026 09:37 👍 6 🔁 5 💬 0 📌 0
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Happy holidays from the @flurylab.bsky.social!🎉 A year with a lot of firsts: first PhD students, first Postdoc, first grant & first farewells - and a first lab move, too! Thanks to my amazing team for the hard work & curiosity!💪🧐👥 Can't wait to tackle more firsts (& seconds) in the coming year(s)!🙌🤩

21.12.2025 22:27 👍 15 🔁 2 💬 0 📌 0
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Science off the bench! 🥳
Here's to our beautiful Christmas wreath — creatively adorned with colorful Falcon caps, mini Eppis, and, of course, our signature artistic yeast plates. 😎🎨

18.12.2025 17:18 👍 4 🔁 0 💬 0 📌 1
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The eukaryotic replisome intrinsically generates asymmetric daughter chromatin fibers DNA replication is molecularly asymmetric, due to distinct mechanisms for lagging and leading strand DNA synthesis. Whether chromatin assembly on newly replicated strands is also asymmetric remains un...

Some (+)ve news to lighten another heavy weekend: our latest preprint (c/o Mattiroli + Ramani labs) is up!
www.biorxiv.org/content/10.1...
A tour-de-force by 1st authors Bruna Eckhardt & @palindromephd.bsky.social, focusing on chromatin replication. RTs welcome; tweetorial in 3,2...(1/n)

20.09.2025 16:10 👍 77 🔁 41 💬 2 📌 2
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Could AI slow science? Confronting the production-progress paradox

Fabulous post by @randomwalker.bsky.social & Sayash raising the same concern many of us have about whether we're on the right track with how we're using AI for science. Everyone should read it, take a deep breath & think through the implications.

www.aisnakeoil.com/p/could-ai-s...

17.07.2025 16:05 👍 158 🔁 69 💬 7 📌 11
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We found a new asymmetry in the large-scale chromosome structure: sister chromatids are systematically shifted by hundreds of kb in the 5′→3′ direction of their inherited strands! The work was led by Flavia Corsi, in close collaboration with the Daniel Gerlich lab.
www.biorxiv.org/content/10.1...
1/

15.07.2025 08:11 👍 115 🔁 59 💬 3 📌 7
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Retrospective and multifactorial single-cell profiling reveals sequential chromatin reorganization during X inactivation - Nature Cell Biology Kefalopoulou, Rullens et al. develop Dam&ChIC to assay chromatin state at two different time points in the same cell. The method was used to study the reorganization of LADs during cell division a...

I am very excited to share our latest work where we describe a new method to profile genome-wide chromatin transitions over time in single cells. Great collaborative effort with the van Oudenaarden group @hubrechtinstitute.bsky.social @oncodeinstitute.bsky.social www.nature.com/articles/s41....

10.07.2025 14:36 👍 111 🔁 30 💬 1 📌 2
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DeepMind’s new AlphaGenome AI tackles the ‘dark matter’ in our DNA Nature - Tool aims to solve the mystery of non-coding sequences — but is still in its infancy.

An AI model developed by Google DeepMind could help scientists make sense of the non-protein-coding part of the genome

https://go.nature.com/4llASRk

29.06.2025 08:34 👍 46 🔁 5 💬 0 📌 1
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3D bioprinting innovation and the patentability hurdle - Nature Biotechnology How are patent examiners in the United States, Europe and Australia interpreting and applying the patentability criteria to specific subject matter related to 3D bioprinting technologies?

3D bioprinting innovation and the patentability hurdle - @uqlaw.bsky.social go.nature.com/4dsBr9i

19.05.2025 15:50 👍 7 🔁 4 💬 1 📌 1
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FISHnet: detecting chromatin domains in single-cell sequential Oligopaints imaging data - Nature Methods FISHnet is a graph-theory-based method for sensitive and specific identification of 3D genome features in sequential Oligopaints data.

Introducing FISHnet, a graph-theory-based method for sensitive and specific identification of chromatin domains from single-cell sequential Oligopaints data.

www.nature.com/articles/s41...

12.05.2025 17:39 👍 6 🔁 1 💬 0 📌 1
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It has been bittersweet last week, when we bid farewell to Pedro and Prasanthi who are embarking on a new adventure!🥹 Thanks a lot for all the hard work and high spirit!🙏

31.03.2025 21:09 👍 4 🔁 1 💬 1 📌 0