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Michael Giolai

@michaelgiolai

Studying plant immunity, its natural variation and consequences · lainelab.net · omiks.it · scholar.google.com/citations?user=KrJkCqoAAAAJ

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18.11.2024
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Latest posts by Michael Giolai @michaelgiolai

Our paper with @mikkotiusanen.bsky.social out now in @oikosjournal.bsky.social 🥳
In the picture we are hard at work collecting data on Mount Calanda 🗻

06.03.2026 16:46 👍 3 🔁 1 💬 0 📌 0

Our Editorial in @embojournal.org

‘EMBO Press co-evolves with molecular ecology and evolutionary biology’ is available online now doi.org/10.1038/s443...

03.03.2026 13:55 👍 3 🔁 1 💬 0 📌 0

There is a week left to apply for two available positions in my lab @ipbhalle.bsky.social

- PhD: ipb-halle.mhm.jobs/12-phd-posit...

- Postdoc: ipb-halle.mhm.jobs/13-postdocto...
Earliest start date: 01/05/2026.

We are interested in plant immune receptor biochemistry and evolution. Please share!

02.03.2026 11:16 👍 33 🔁 39 💬 0 📌 0
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Announcing the publication of TAIR12: Consult the fully reannotated genome on the European Nucleotide Archive - Phoenix Bioinformatics TAIR (The Arabidopsis Information Resource), together with our nonprofit host Phoenix Bioinformatics, is pleased to announce the public release of TAIR12

🎉📣 #TAIR12, the latest reannotation of the Arabidopsis thaliana genome, is now available under accession number PRJEB100887 on ENA and NCBI!

Thank you all the volunteer researchers whose hard work has made this possible!

#plantscience #plantbiology 🧪

bit.ly/3ZHtneT

19.02.2026 18:40 👍 97 🔁 59 💬 3 📌 2

How do bacterial pangenomes evolve, what controls their dynamics, why do they exist?
Fitting a mechanistic model to 450 species from allthebacteria.org suggesting fast vs slow gene exchange (i.e. amount of MGEs) is a major differentiating factor, correlated with phylogeny rather than lifestyle

09.02.2026 10:55 👍 71 🔁 32 💬 1 📌 0
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EVENT - OPEN Friday Seminar - HOPWOOD LECTURE: Prof. Julia Vorholt, ETH Zurich - "Establishing causality: Opportunities of synthetic communities for plant microbiome research"

🗓️ 13 February 2026
⏰ 11:30 am - 12:30 pm
💻 Register to join online: okt.to/s7xUb5

06.02.2026 13:50 👍 2 🔁 4 💬 0 📌 0
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Postdoctoral Researcher in Biodiversity Economics Postdoctoral Researcher in Biodiversity Economics

Open Postdoctoral Researcher position in Biodiversity Economics for a new collaboration between @rececochange.bsky.social and Environmental and resource economics group @helsinki.fi
DL 18 February

jobs.helsinki.fi/job/Helsinki...

05.02.2026 11:08 👍 3 🔁 7 💬 0 📌 0
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Please share!
My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th!
uni-tuebingen.de/universitaet...

30.01.2026 13:56 👍 83 🔁 118 💬 0 📌 3

This article is now published! academic.oup.com/nargab/artic...
We’ve added a few new analyses. First off, we show that, while gene presence absence variation (PAV) scales with evolutionary distance in both plants and animals, the base level and rate of accrual are both twice as high in plants.

30.01.2026 12:41 👍 23 🔁 17 💬 2 📌 0
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Plant Pathogens Moonlighting as Beneficial Insect Symbionts Herbivorous insects can shape the epidemiology of disease in plants by vectoring numerous phytopathogens. While the consequences of infection are often well-characterized in the host plant, the extent...

Can plant pathogens boost vector fitness?

Together with @hassansalem.bsky.social, we review how phytopathogens can spread further by moonlighting as insect symbionts 🪲 More on this nifty lifestyle in @annualreviews.bsky.social!

www.annualreviews.org/content/jour...

02.02.2026 07:48 👍 40 🔁 28 💬 1 📌 1
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Please share!
PhD position (4 years) available in my group @zmbp-tuebingen.bsky.social. We look for candidates with solid aptitude in computer science to cross disciplines and use cutting edge imaging to understand host infection by destructive plant pathogens.
uni-tuebingen.de/universitaet...

30.01.2026 15:04 👍 48 🔁 69 💬 2 📌 1
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Multiple protein structure alignment at scale with FoldMason Protein structure is conserved beyond sequence, making multiple structural alignment (MSTA) essential for analyzing distantly related proteins. Computational prediction methods have vastly extended ou...

FoldMason is out now in @science.org. It generates accurate multiple structure alignments for thousands of protein structures in seconds. Great work by Cameron L. M. Gilchrist and @milot.bsky.social.
📄 www.science.org/doi/10.1126/...
🌐 search.foldseek.com/foldmason
💾 github.com/steineggerla...

30.01.2026 06:11 👍 300 🔁 147 💬 4 📌 3
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Does local adaptation shape community assembly?

Our new study led by @maijajoki.bsky.social available now! We combine viruses, the Åland metapopulation & HMSC modeling to uncover eco-evo drivers of within-host pathogen diversity 🦠

doi.org/10.32942/X2G...
@erc.europa.eu @rececochange.bsky.social

30.01.2026 06:41 👍 8 🔁 4 💬 0 📌 0
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1/12 I'm ecstatic to share my preprint on legume NLR tissue expression! We investigated the NLRomes of 28 legumes + 4 outgroups, examining tissue expression across 7 legume species. Paper thread below 🧵👇
@thesainsburylab.bsky.social @itqbnova.bsky.social
🔗https://doi.org/10.64898/2026.01.25.701577

29.01.2026 11:05 👍 52 🔁 22 💬 3 📌 1
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Diversify and conquer: How effector diversity is shaped by host–microbe co-evolution

Thank you
@marioncmueller.bsky.social, @binebrumm.bsky.social, Eric Kemen, Yiheng Hu and Thomas Lahaye for this nice common effort on effector diversity.

Diversify and conquer: How effector diversity is shaped by host–microbe co-evolution
doi.org/10.1371/jour...

24.01.2026 15:21 👍 19 🔁 12 💬 0 📌 2
Victorian-style AI slop. A small girl in a blue dress whose name is not Alice for copyright reasons stands in a forest and stares up at an absurdly giant mushroom, surrounded by many other biologically inaccurate fungi. The scene attempts to hint at fungal diversity, scale, and deep evolutionary relationships. Roughly what happens when you reanalyze ~2,000 fungal genomes and realize how much biology is still hiding in the woods.

Victorian-style AI slop. A small girl in a blue dress whose name is not Alice for copyright reasons stands in a forest and stares up at an absurdly giant mushroom, surrounded by many other biologically inaccurate fungi. The scene attempts to hint at fungal diversity, scale, and deep evolutionary relationships. Roughly what happens when you reanalyze ~2,000 fungal genomes and realize how much biology is still hiding in the woods.

What can we learn from comparing ~2,000 fungal genomes?

Find out about:

🍄evolutionary transitions
🍄lifestyles
🍄genome dynamics
🍄sampling gaps
🍄efforts to uncover the remaining fungal dark matter

New review by @jgi.doe.gov's Stephen Mondo and Igor Grigoriev

www.nature.com/articles/s41...

20.01.2026 20:34 👍 10 🔁 7 💬 0 📌 0
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New paper led by @hannasusi.bsky.social shows biodiversity responses to carbon farming are highly context-dependent—varying by management, index and taxa 🌱🪱🐞🐦.

Abundance is the most sensitive early indicator for detecting biodiversity impacts!

www.sciencedirect.com/science/arti...

19.01.2026 08:16 👍 7 🔁 5 💬 0 📌 1

TF-MINDI is out! A new method to learn cis-regulatory codes through rich embeddings of TF binding sites. TF-MINDI decomposes motif neighbourhoods, and works downstream of any sequence-to-function deep learning model. We deeply study the enhancer code in human neural development, check out the thread

15.01.2026 12:32 👍 60 🔁 38 💬 1 📌 0
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New alleles of Arabidopsis BIK1 reinforce its predominant role in pattern-triggered immunity and caution interpretations of other reported functions - Nature Plants Thorough genetic analyses by four laboratories reinforce the central role of the protein kinase BIK1 in plant immunity. Other unrelated functions proposed for BIK1, however, are associated with genome...

www.nature.com/articles/s41...

15.01.2026 20:36 👍 5 🔁 1 💬 0 📌 0
A graph showing daily temperature anomalies since the 1940s

A graph showing daily temperature anomalies since the 1940s

Not a single day in 2025 was cooler than the 1991-2020 average, on a global scale. @copernicusecmwf.bsky.social

14.01.2026 21:27 👍 391 🔁 311 💬 5 📌 23
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TSL Summer Conference in Plant-Microbe Interactions, 20th – 31st July… Inviting Early Career Researchers to join international experts in discussing the latest approaches and discoveries in Plant-Microbe Interactions …

Join us in Norwich this July for the TSL Summer Conference in Plant-Microbe Interactions! ☀️🌱🧬

Discuss the latest approaches & discoveries in plant health with international keynote and local speakers.

APPLY by 30 March '26 ⬇️ Click link for more info
www.tsl.ac.uk/tsl-summer-c...

14.01.2026 17:50 👍 29 🔁 30 💬 1 📌 4
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Here @mikkotiusanen.bsky.social in action collecting this impressive dataset on Calanda

15.01.2026 08:00 👍 3 🔁 1 💬 0 📌 1

Out now 🥳 our study led by @mikkotiusanen.bsky.social!
With data on 1.17 M flowers & 10,000 pollinators 🌼🐝 we show plant–pollinator timing shifts from biotic to abiotic control along alpine gradients ➡️climate change may rewire interaction synchrony
nsojournals.onlinelibrary.wiley.com/doi/10.1002/...

15.01.2026 07:41 👍 12 🔁 4 💬 2 📌 1
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Postdoctoral Researcher (Carella Group) | John Innes Centre An exciting opportunity has arisen for a Postdoctoral Researcher to join the Carella Group at the John Innes Centre, working on cutting-edge science in the field of Evo-MPMI (Evolutionary Molecular…

We have an open POSTDOC position to explore Marchantia immune receptor biology that is closing on the 18th of Jan. Apply using the link below, and/or email me for more details. www.jic.ac.uk/vacancies/po...

13.01.2026 11:31 👍 39 🔁 58 💬 0 📌 1
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Out after peer review, led by @shanshanwang3.bsky.social.
Gating of immune responses in Arabidopsis mesophyll cells: after initial response, immune gene expression stays hi in some cells, while during PTI other cells reinitiate a growth-related program.
nph.onlinelibrary.wiley.com/doi/10.1111/...

08.01.2026 10:59 👍 45 🔁 15 💬 1 📌 1
REC Newsletter 1/2026

I’m excited to share with you the first @rececochange.bsky.social newsletter, highlighting recent research on biodiversity change, policy-relevant insights and news from across the REC community 💚🌍

Read it here 👉 mailchi.mp/97ed6942f5b8...

07.01.2026 10:54 👍 7 🔁 4 💬 0 📌 1
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Info event: International Climate Protection Fellowship If you would like to learn more about the International Climate Protection Fellowship, join our online event by Zoom and get all the information on the programme and the application process first-hand...

The Alexander von Humboldt foundation has a call for Climate Protection Fellowships. Information event is tomorrow!
www.humboldt-foundation.de/en/connect/i...

If you are interested in working on a project related to quantitative disease resistance and climatic trade offs, I could possibly be host!

06.01.2026 14:18 👍 8 🔁 4 💬 0 📌 0
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Towards a quantitative view of NLR evolution in genome space -- check out where we think the field of #NLR #evolution research is heading in this review led by Luzie Wingen and Aurélien Tellier.
ecoevorxiv.org/repository/v...
#plantscience

06.01.2026 09:05 👍 26 🔁 18 💬 0 📌 0
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From microscale to microbial insights: validating high-throughput microvolume extraction (HiMEx) methods for marine microbial ecology Abstract. Extracting and directly amplifying DNA from small-volume, low-biomass samples would enable rapid, ultra-high-throughput analyses, facilitating th

Think you need large volumes for microbial experiments?
Our recent publication introduces HiMEx, a simple, scalable method for microbial ecology. academic.oup.com/ismecommun/a...
🦠 it provides an easy, efficient approach to capturing viral diversity, opening new opportunities for virome analysis.

31.12.2025 20:53 👍 23 🔁 14 💬 1 📌 1
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New Article: "A biosynthetic gene cluster for three post-chorismate pathways in Arabidopsis" rdcu.be/eXEMY

Non-aromatic, chorismate-derived compounds, abundant in the roots of Arabidopsis, are made by a biosynthetic gene cluster comprising five adjacent genes.

05.01.2026 15:53 👍 6 🔁 5 💬 0 📌 0