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Ashlee Feng

@xashleefeng

Postdoc @ Lacra Bintu Lab

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Posts 06.08.2025
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Latest posts by Ashlee Feng @xashleefeng

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GAGA zinc finger transcription factor searches chromatin by 1D–3D facilitated diffusion - Nature Structural & Molecular Biology Single-molecular microscopy shows that GAGA multimeric zinc finger transcription factor searches chromatin for cognate sites through rapid one-dimensional sliding on free DNA (which can be blocked by ...

Full article here: www.nature.com/articles/s41...

19.08.2025 22:27 👍 0 🔁 0 💬 0 📌 0
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Nucleosomes constrain 1D DNA diffusion by eukaryotic transcription factors - Nature Structural & Molecular Biology The transcription factor GAGA factor (GAF) recruits chromatin remodelers to establish and maintain open chromatin for transcription in Drosophila melanogaster. In searching for DNA targets, GAF underg...

A brief summary/perspective on my recently published PhD work: www.nature.com/articles/s41...

19.08.2025 22:27 👍 0 🔁 0 💬 1 📌 0