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Féaron Cassidy, PhD

@fearoncassidy

💼DOROTHY EU COFUND fellow 🔵Physoc Trustee 👂🏼Pronounced “Fair-on” 🌏Karolinksa Institute, Sweden previously Maynooth Uni IRL, Uni of Galway IRL, QMUL London UK, Uni of Nottingham UK, TCD Dublin IRL 🥼obesity-assoc cancer immunology ❤️wild swimming ⚧️She/her

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30.11.2024
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Latest posts by Féaron Cassidy, PhD @fearoncassidy

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⏳ Deadline Jan. 14 (11:59 PM MST)! Submit abstracts/apply for scholarships for Tumor Microenvironment / Inflammation Resolution.

🔗 keysym.us/KSTumorMicro26
| keysym.us/KSInflammati...

@coussenslab.bsky.social @sandramcallister.bsky.social @laurakiessling.bsky.social @magarianblander.bsky.social

12.01.2026 18:14 👍 5 🔁 3 💬 0 📌 2
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The Town That Asbestos Built. The Cancer It Left Behind | The Tyee Former residents of Cassiar say they weren’t warned about the risks. Now, they struggle to find support.

Cassiar, BC, was an idyllic place to grow up.

More than 30 years after the asbestos mine closed, some former residents believe their cancer diagnosis is linked to their time there — and they struggle to find supports.

First in a two-part @thetyee.ca series:
thetyee.ca/News/2026/01...

12.01.2026 17:37 👍 24 🔁 16 💬 5 📌 1

Can never repost this 2025 finding enough:

91,000 deaths EVERY YEAR in the United States are caused by air pollution from oil and gas.

That’s 250 funerals a day

That’s the human sacrifice required for running our economy via extracting and burning fossilized Devonian corpses

You good with that?

12.01.2026 18:33 👍 35 🔁 19 💬 1 📌 1
USDA
U.S. DEPARTMENT OF AGRICULTURE
DATE:
November 8, 2025
SUBJECT: Updated Supplemental Nutrition Assistance Program (SNAP)
November Benefit Issuance
TO:
Regional Directors
SNAP Division
All Regions
SNAP State Agency Directors
All State Agencies
This memorandum is a follow up to the guidance shared on October 10, October 24, November 4, November 5, and November 7, 2025, regarding Supplemental Nutrition Assistance Program (SNAP) benefits for November 2025.
The U.S. Supreme Court granted the U.S. Department of Agriculture an administrative stay of the orders issued by the District Court of Rhode Island in Rhode Island State Council of Churches, et al. v. Rollins, 25-cv-569. Pending any explicit direction to the contrary from Food and Nutrition Service (FNS), States must not transmit full benefit issuance files to EBT processors. Instead, States must continue to process and load the partial issuance files that reflect the 35 percent reduction of maximum allotments detailed in the November 5 guidance.
To the extent States sent full SNAP payment files for November 2025, this was unauthorized. Accordingly, States must immediately undo any steps taken to issue full SNAP benefits for November 2025. Please advise the appropriate FNS Regional Office representative of steps taken to correct any actions taken that do not comply with this memorandum.
Per 7 CFR 271.7(h), failure to comply with this memorandum may result in USDA taking various actions, including cancellation of the Federal share of State administrative costs and holding States liable for any overissuances that result from the noncompliance.

USDA U.S. DEPARTMENT OF AGRICULTURE DATE: November 8, 2025 SUBJECT: Updated Supplemental Nutrition Assistance Program (SNAP) November Benefit Issuance TO: Regional Directors SNAP Division All Regions SNAP State Agency Directors All State Agencies This memorandum is a follow up to the guidance shared on October 10, October 24, November 4, November 5, and November 7, 2025, regarding Supplemental Nutrition Assistance Program (SNAP) benefits for November 2025. The U.S. Supreme Court granted the U.S. Department of Agriculture an administrative stay of the orders issued by the District Court of Rhode Island in Rhode Island State Council of Churches, et al. v. Rollins, 25-cv-569. Pending any explicit direction to the contrary from Food and Nutrition Service (FNS), States must not transmit full benefit issuance files to EBT processors. Instead, States must continue to process and load the partial issuance files that reflect the 35 percent reduction of maximum allotments detailed in the November 5 guidance. To the extent States sent full SNAP payment files for November 2025, this was unauthorized. Accordingly, States must immediately undo any steps taken to issue full SNAP benefits for November 2025. Please advise the appropriate FNS Regional Office representative of steps taken to correct any actions taken that do not comply with this memorandum. Per 7 CFR 271.7(h), failure to comply with this memorandum may result in USDA taking various actions, including cancellation of the Federal share of State administrative costs and holding States liable for any overissuances that result from the noncompliance.

The US Department of Agriculture has ordered that "states must immediately undo any steps taken to issue full SNAP benefits for November 2025".

09.11.2025 17:50 👍 287 🔁 122 💬 60 📌 51
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Can Understanding Misogyny Stop Gun Violence? - With Cynthia Miller Idriss Podcast Episode · Real Feels - Modern Masculinity with Brad Gage · 10/28/2025 · 36m

Can better understanding misogyny stop gun violence? @bradgage.bsky.social talks to extremism expert and Man Up author @milleridriss.bsky.social for the Real Feels podcast:

31.10.2025 19:52 👍 6 🔁 2 💬 0 📌 0
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TCR signaling via NFATc1 constrains IL-15-induced bystander activation of human memory CD8+ T cells Memory CD8+ T cells can undergo TCR-dependent or -independent activation. Here, Lee et al. show that IL-15-induced bystander activation of human memory CD8+ T cells is suppressed by concurrent TCR signaling through NFATc1-AP-1 interactions. Furthermore, they validate a bystander activation gene set induced by IL-15 and decreased upon TCR stimulation.

Online now: TCR signaling via NFATc1 constrains IL-15-induced bystander activation of human memory CD8+ T cells

31.10.2025 19:55 👍 7 🔁 4 💬 0 📌 0
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Phagocytosis: a process that shapes immune responses to engulfed meals - Nature Reviews Immunology In this Review, Li and Underhill discuss recent advances in understanding the process of phagocytosis. The authors highlight how phagocytosis is integral for innate immune sensing and explain how the ...

www.nature.com/articles/s41...

PDF

www.nature.com/articles/s41...

31.10.2025 19:56 👍 2 🔁 1 💬 0 📌 0
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Competitive catabolism in systemic metabolic homeostasis Systemic metabolic homeostasis maintains circulating nutrient concentrations within physiological ranges. Insulin is central to this process, lowering circulating levels of glucose, free fatty acids, ...

excited to read this preprint from rabinowitz lab- how does the body decide which nutrients are burned, and how can this go wrong in T2 diabetes?
www.biorxiv.org/content/10.1...

31.10.2025 19:40 👍 14 🔁 3 💬 0 📌 1

Every time someone says “We DoNt kNoW hOw To Do GoOd ScICoMm!” a meteorologist loses their wings**.

**shit

21.10.2025 12:36 👍 15 🔁 2 💬 0 📌 0
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Peanut Allergies Have Plummeted in Children, Study Shows

"43% drop in peanut allergies"

Good example of how science evolves.

And "how a public health recommendation can change children’s health.”

And how good research (support, pls) informs policy.

Peanut Allergies Have Plummeted in Children, Study Shows www.nytimes.com/2025/10/20/w...

20.10.2025 20:07 👍 167 🔁 50 💬 6 📌 7

Early intro to diet no doubt a huge effect, is there also a role for reduced use of peanut oil in baby ointments?

20.10.2025 20:36 👍 0 🔁 0 💬 0 📌 0

Oh here’s another hill I like to die on.

No outdoor cats. If you have outdoor cats you’re a self absorbed asshole and should not be allowed to have pets.

20.10.2025 03:27 👍 161 🔁 12 💬 34 📌 4
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Meanwhile in the UK

"Do you think it was wrong to leave the EU?"

"Yes."

"And yet you would vote for the people who told you leaving the EU is a good idea?"

"Sure, why not?"

20.10.2025 10:22 👍 13 🔁 4 💬 2 📌 1

Super interesting! What do you think could be the reason for this difference in response? And did you look at far red?

20.10.2025 12:37 👍 0 🔁 0 💬 1 📌 0
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Our newest publication is out, and it is most certainly a colorful one!!

Using carefully controlled experiments in keratinocytes, we show that different light wavelengths affect cell metabolism and integrity in different manners.

febs.onlinelibrary.wiley.com/doi/10.1002/...

20.10.2025 09:39 👍 16 🔁 6 💬 2 📌 1
My linocut print of mathematician & astronomer Nicole-Reine Lepaute (1723-1788) in a vertical gradient (bottom to top) of bright pink to lavender on white paper. She wears a wig and gown and the portrait is from the chest to head. Her 12 diagrams of the phases of the annular the solar eclipse of 1764 as viewed from Paris appear across her shoulders. Behind her head in green is her map of the path of the eclipse across Europe.

My linocut print of mathematician & astronomer Nicole-Reine Lepaute (1723-1788) in a vertical gradient (bottom to top) of bright pink to lavender on white paper. She wears a wig and gown and the portrait is from the chest to head. Her 12 diagrams of the phases of the annular the solar eclipse of 1764 as viewed from Paris appear across her shoulders. Behind her head in green is her map of the path of the eclipse across Europe.

For day 12 of #spacetober_challenge prompt eclipse: #mathematician & #astronomer Nicole-Reine Lepaute (1723-1788) and her calculated path of the solar eclipse of 1764. 🧪🐡👩🏼‍🔬🧮🔭 #histsci She also worked with Alexis Clairaut & Jérôme Lalande to precisely calculate the date of return of Halley’s Comet, 🧵

12.10.2025 12:25 👍 78 🔁 22 💬 1 📌 3
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Maldives becomes the first country to achieve ‘triple elimination’ of mother-to-child transmission of HIV, syphilis and hepatitis B In a landmark public health achievement, WHO has validated the Maldives for eliminating mother-to-child transmission (EMTCT) of hepatitis B, while maintaining its earlier validation (in 2019) for EMTCT of HIV and syphilis. This makes the Maldives the first country in the world to achieve ‘triple elimination’.

Awesome public health news:
Maldives becomes the first country to achieve ‘triple elimination’ of
1. mother-to-child transmission of HIV,
2. Syphilis and
3. Hepatitis B
www.who.int/news/item/13...

14.10.2025 11:43 👍 362 🔁 105 💬 1 📌 6

Remarkable recovery of the Klamath River salmon. Many thanks to the agencies, Tribes, and NGOs who came together to remove dams and monitor the recovery of the Klamath River salmon. And kudos, too, to the indigenous youth who paddled source to sea on the newly freed river

14.10.2025 04:49 👍 140 🔁 53 💬 3 📌 1

I am open to the idea that there are people who don't have and don't want to gain the skills to engage directly with their data but every single day that I do I learn the answer to a question you'd never even think to ask unless you were personally staring into the abyss of an uncleaned dataset.

10.10.2025 18:35 👍 80 🔁 11 💬 5 📌 2
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Structural insights into GTP-coupled conformational changes in Mfn1 revealed by time-resolved transition metal ion FRET. Outer mitochondrial membrane fusion is mediated by the mitofusin paralogs Mfn1 and Mfn2. Nucleotide-driven self-assembly and conformational changes are required for regulated membrane fusion activity,...

Genuinely thrilled to share our new story with the world - an amazing collaboration with @profsharona.bsky.social and Bill Zagotta using their innovative FRET technique to study mitofusin conformational changes. Huge credit to Sophie Hurwitz for tackling this project. urldefense.com/v3/__https:/...

10.10.2025 18:31 👍 9 🔁 5 💬 2 📌 0
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Tertiary lymphoid structures support the development of allergen-specific progenitor CD4+ T cells Tissue-resident memory CD4+ T cells (TRM) are key sentinels of the adaptive immune response that provide a rapid, robust inflammatory response upon reactivation in non-lymphoid tissues. While CD4+ TRM...

Asthma is a chronic disease characterized by acute, intermittent, recurrent episodes of airway inflammation. A decade of work developing the tools, techniques and collaborations needed to figure out how CD4+ T cells in the lungs propagate disease can be found here:
www.biorxiv.org/content/10.1...

10.10.2025 19:22 👍 43 🔁 17 💬 1 📌 1
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Nobel peace prize winner Maria Corina Machado: Venezuelan opposition leader forced into hiding after taking on Maduro The Venezuelan opposition leader was forced to go into hiding in 2024 after being banned form standing in that year’s election.

The Venezuelan opposition leader was forced to go into hiding in 2024 after being banned form standing in that year’s election.

10.10.2025 19:28 👍 20 🔁 10 💬 4 📌 0
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More than 30% of this century’s science Nobel prizewinners immigrated: see their journeys The most common destination for eventual Nobel laureates in physics, chemistry and medicine since 2000 is the United States, Nature has found.

Immigrant scientists make a massive contribution wherever they go

More than 30% of this century’s science Nobel prizewinners immigrated

www.nature.com/articles/d41...

10.10.2025 18:46 👍 105 🔁 43 💬 2 📌 1

"We're doing the studies to make the proof."

This is not how Gold Standard Science works. Or any science. You do the study to TEST THE HYPOTHESIS, not to prove yourself right.

09.10.2025 18:41 👍 71 🔁 17 💬 5 📌 0
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Implantation is inherently a mechanical process. We find contractility is necessary and sufficient for spreading behaviors. We can artificially age embryos from young females and even rescue aged embryo spreading just by tuning contractility!

01.10.2025 18:20 👍 8 🔁 2 💬 1 📌 0

THIS IS THE WAY.

Everyone gets their knickers in a twist when I say we can’t sci-comm our way out of this mess…but maybe you’ll listen to the more eloquent and measured @edyong209.bsky.social!

This isn’t happening because people don’t appreciate the brilliance of the double helix structure.

01.10.2025 22:51 👍 44 🔁 20 💬 2 📌 0

The remarkable number of people, me included, who were inspired by her work, life and example is the biggest tribute. Find a way to honor her memory. The wolrd is a bit smaller and sadder with her gone

01.10.2025 23:13 👍 46 🔁 5 💬 1 📌 0

The language of non-consent around AI is really telling. "It's too late to be scared." "It's here whether we want it or not." "You'll have to learn to work with it." "You can't fight the inevitable."

All just variations of "you're not allowed to say no." Creepy technology made by creepy people.

01.10.2025 15:37 👍 3941 🔁 1608 💬 49 📌 56
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What is a reactionary centrist, and does the UK have them? A term favoured by US progressives can help us understand Britain’s drift to the right

"In 2012, 60 trans-related articles were published by Britain’s media. By 2022, it was more than 7,500, according to figures from Trans Media Watch. The media is not responding to public rage against vulnerable minorities; it is helping to create it." www.prospectmagazine.co.uk/politics/709...

01.10.2025 13:52 👍 473 🔁 170 💬 4 📌 12
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NLRP3 is a thermosensor that is negatively regulated by high temperature Inflammation is an essential response to infection and injury, but unregulated inflammation is damaging and must be limited by negative feedback signalling. Inflammasome signalling drives local inflam...

Check out this new thermo-hot paper from the @colllab.bsky.social Lab. Glad to contribute and work with her team.

www.biorxiv.org/content/10.1...

01.10.2025 06:56 👍 8 🔁 4 💬 2 📌 0